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2. Collective homeostasis of condensation-prone proteins via their mRNAsRupert Faraway, Neve Costello Heaven, Holly Digby, Klara Kuret, Jure Rebselj, Oscar G. Wilkins, Anob M. Chakrabarti, Ira Alexandra Iosub, Neža Vadnjal, Rhys Dore, Lea Knez, Stefan Ameres, Clemens Plaschka, Jernej Ule, 2025 Objavljeno: 19.01.2026; Ogledov: 490; Prenosov: 711
 Celotno besedilo (21,45 MB)
Prenosov v tednu: 193 |
3. High-Intensity Fast-Response Electric Radiant Panel (HIFREP) to impose fire equivalent heat fluxes on building elements with enhanced thermal boundary conditions accuracyFlorian Put, Balša Jovanović, Evelien Symoens, Andrea Lucherini, Bart Merci, Ruben Van Coile, 2025 Opis: Bench-scale fire testing has gained popularity as a highly controllable and cost-effective solution, overcoming many of the shortcomings of traditional large-scale fire resistance tests. Whereas gas-fired radiant panels have demonstrated significant success in this area, the present study introduces a novel High-Intensity Fast-Response Electric radiant Panel (HIFREP). Utilizing electrically operated radiation emitters, it provides more precise and quasi-instantaneous control over the thermal boundary conditions. HIFREP delivers high and stable heat fluxes up to 105 kW/m2 , and, due to the low thermal inertia of the emitters, can rapidly adjust its output to changes in the input. In this regard, the time constant of the emitters has been found to be less than 1 s, both during heating and cooling. It eliminates gas combustion and hence avoids the need for extraction hoods when testing the fire performance of non-combustible materials, making it suitable for traditional structural testing laboratories. The presented High-Intensity Fast-Response Electric radiant Panel also provides a reliable tool for the validation of FEM simulation results by accurately replicating the thermal boundary conditions in structural fire engineering analyses.
Ključne besede: radiant panel, fire testing, heat transfer, radiation, heat flux, thermal boundary conditions
Objavljeno: 16.06.2025; Ogledov: 843; Prenosov: 434
Celotno besedilo (1,98 MB)
Prenosov v tednu: 163 |
4. Environmental factors influence cross-talk between a heat shock protein and an oxidative stress protein modification in the lizard Gallotia gallotiEdward Gilbert, Anamarija Žagar, Marta López-Darias, Rodrigo Megía-Palma, Karen A. Lister, Max Dolton Jones, Miguel A. Carretero, Nina Guerra Serén, Pedro Beltran-Alvarez, Katharina C. Wollenberg-Valero, 2024 Opis: Better understanding how organisms respond to their abiotic environment, especially at the biochemical level, is critical in predicting population trajectories under climate change. In this study, we measured constitutive stress biomarkers and protein post-translational modifications associated with oxidative stress in Gallotia galloti, an insular lizard species inhabiting highly heterogeneous environments on Tenerife. Tenerife is a small volcanic island in a relatively isolated archipelago off the West coast of Africa. We found that expression of GRP94, a molecular chaperone protein, and levels of protein carbonylation, a marker of cellular stress, change across different environments, depending on solar radiation-related variables and topology. Here, we report in a wild animal population, cross-talk between the baseline levels of the heat shock protein-like GRP94 and oxidative damage (protein carbonylation), which are influenced by a range of available temperatures, quantified through modelled operative temperature. This suggests a dynamic trade-off between cellular homeostasis and oxidative damage in lizards adapted to this thermally and topologically heterogeneous environment.
Objavljeno: 17.05.2024; Ogledov: 1506; Prenosov: 1202
Celotno besedilo (1,83 MB)
Prenosov v tednu: 160 |
5. Intravenous thrombolysis for ischemic stroke in the posterior circulationRobrecht R. M. M. Knapen, Senta Frol, Sander M.J. van Kuijk, Janja Pretnar-Oblak, Christiaan van der Leij, Robert J. van Oostenbrugge, Wim H. van Zwam, 2024 Ključne besede: Intravenous thrombolysis, ischemic stroke, posterior circulation
Objavljeno: 12.06.2026; Ogledov: 84; Prenosov: 178
Celotno besedilo (3,30 MB)
Prenosov v tednu: 124 |
6. Fitocenološka analiza gozdnih sestojev evropskega pravega kostanja (Castanea sativa) v Slovenski IstriIgor Dakskobler, Zvone Sadar, 2020 Opis: Fitocenološko smo analizirali gozdne sestoje v Slovenski Istri, v katerih v drevesni plasti prevladuje pravi kostanj (Castanea sativa). Našli smo jih v okolici vasi Puče (med Šmarjami in Koštabono) v porečju Drnice, v povodjih potoka Malinska (med Gradinom in Abitanti, blizu vasi Stara Mandrija) in v povodju potoka Pregon (južno od Pregare pri vaseh Reparec in Tuniši). Na podlagi primerjave s podobnimi kostanjevimi gozdovi na Hrvaškem in v Bosni smo jih uvrstili v asociacijo Helleboro istriaci-Castaneetum sativae Medak 2009 in v dve novi subasociaciji: -ornithogaletosum pyrenaici in -ruscetosum aculeati. Po naših spoznanjih so preučeni sestoji drugotni, pionirski ali degradacijski stadiji na nekoč najbrž bukovih ali hrastovih rastiščih iz asociacij Ornithogalo pyrenaici-Fagetum, Seslerio autumnalis-Fagetum in Seslerio autumnalis-Quercetum petraeae. Ker pa se pravi kostanj v njih pomlajuje in ohranja več generacij, jih je mogoče vrednotiti tudi kot poseben habitatni in/ali gozdni rastiščni tip, a presojo o tem prepuščamo pristojnim strokovnjakom.
Ključne besede: fitocenologija, sinsistematika, Helleboro istriaci-Castaneetum sativae, Carpinion orientalis, Istra, Slovenija
Objavljeno: 14.01.2026; Ogledov: 425; Prenosov: 702
Celotno besedilo (8,29 MB)
Prenosov v tednu: 113 |
7. A practical method to incorporate scour hole shape effects in Winkler-type pile foundation models for bridgesMirko Kosič, Luke J. Prendergast, Andrej Anžlin, 2025 Opis: Scour erosion continues to cause significant issues for the stability and lifespan of bridges worldwide. In Slovenia, extreme flooding in 2023 caused the collapse or failure of many bridges, primarily due to scour, which was exacerbated by debris accumulation. Despite advances in predicting and monitoring scour, it remains among the top reasons for the failure of bridges during flooding. Recent advances in vibration-based health monitoring suggest that scour erosion can be detected using methods such as changes in natural frequency, mode shapes, flexibility-based deflection, and other approaches using offline sensors such as passing vehicle responses. Many of these methods have been trialled numerically where scour is implemented as a reduction in the soil level (or stiffness) around a given bridge foundation. The most common way to model scour is to lower the soil level around a foundation, however, this ignores any contribution that the scour hole shape makes to the stiffness and strength of the soil beneath the scour hole. This paper investigates how the shape of scour holes influences the stiffness and strength of the remaining soil to understand the impact on the modal behaviour of a bridge. A numerical model of a bridge is developed where scour is implemented by removing Winkler springs from the model, and different scour hole shapes are considered in terms of how the remaining overburden influences the stiffness and strength of the soil springs. Scour hole shape properties are considered by means of varying the depth, width, and slope angle of the hole around a given foundation element. For the analyses in this paper, different scour hole shapes are implemented on an example bridge corresponding to local scour holes with narrow width; wider local scour holes; and general scour, where the full soil layer is removed (infinite width). The changes in the modal periods and mode shapes of the bridge in the traffic and river flow directions are assessed to understand the impact of the different scour types on the vibration characteristics.
Ključne besede: scour, dynamics, overburden, frequency, damage, bridges, scour hole shape
Objavljeno: 13.01.2026; Ogledov: 401; Prenosov: 696
Celotno besedilo (10,37 MB)
Prenosov v tednu: 112 |
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