Izpis gradiva

A+ | A- | | SLO | ENG

Naslov: The role of extracellular vesicles in phenotypic cancer transformation Avtorji: ID Ogorevc, Eva (Avtor) ID Kralj-Iglič, Veronika (Avtor) ID Veranič, Peter (Avtor) Datoteke: URL - Izvorni URL, za dostop obiščite https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794874/   PDF - Predstavitvena datoteka, prenos (864,38 KB) MD5: BFB6198050508AD1681F277D84B988D8   Jezik: Angleški jezik Tipologija: 1.02 - Pregledni znanstveni članek Organizacija: OI - Onkološki inštitut Ljubljana Povzetek: Background. Cancer has traditionally been considered as a disease resulting from gene mutations. New findings in biology are challenging gene-centered explanations of cancer progression and redirecting them to the non-genetic origins of tumorigenicity. It has become clear that intercellular communication plays a crucial role in cancer progression. Among the most intriguing ways of intercellular communication is that via extracellular vesicles (EVs). EVs are membrane structures released from various types of cells. After separation from the mother membrane, EVs become mobile and may travel from the extracellular space to blood and other body fluids. Conclusions. Recently it has been shown that tumour cells are particularly prone to vesiculation and that tumour-derived EVs can carry proteins, lipids and nucleic acids causative of cancer progression. The uptake of tumour-derived EVs by noncancerous cells can change their normal phenotype to cancerous. The suppression of vesiculation could slow down tumour growth and the spread of metastases. The purpose of this review is to highlight examples of EV-mediated cancer phenotypic transformation in the light of possible therapeutic applications. Status publikacije: Objavljeno Verzija publikacije: Objavljena publikacija Datum objave: 01.09.2013 Založnik: Association of Radiology and Oncology Leto izida: 2013 Št. strani: str. 197-205 Številčenje: Vol. 47, no. 3 Izvor: Ljubljana PID: 20.500.12556/DiRROS-18593  UDK: 576:616-006 ISSN pri članku: 1318-2099 DOI: 10.2478/raon-2013-0037  COBISS.SI-ID: 269123584  Avtorske pravice: by Authors Opomba: Naslov v kazalu in el. verziji se razlikuje od naslova članka na str. 197; Izvleček in vzporedni stvarni naslov v slov. na str. I-VII; Besedilo članka v angl.; Datum objave v DiRROS: 03.04.2024 Število ogledov: 70 Število prenosov: 29 Metapodatki:     Citiraj gradivo Navadno besedilo BibTeX EndNote XML EndNote/Refer RIS ABNT ACM Ref AMA APA Chicago 17th Author-Date Harvard IEEE ISO 690 MLA Vancouver : Kopiraj citat

Objavi na: Postavite miškin kazalec na naslov za izpis povzetka. Klik na naslov izpiše podrobnosti ali sproži prenos.

Gradivo je del revije

Naslov:	Radiology and oncology
Skrajšan naslov:	Radiol. oncol.
Založnik:	Slovenian Medical Society - Section of Radiology, Croatian Medical Association - Croatian Society of Radiology
ISSN:	1318-2099
COBISS.SI-ID:	32649472

Sekundarni jezik

Jezik:	Slovenski jezik
Naslov:	[Pomen zunajceličnih veziklov v rakasti transformaciji celic]
Ključne besede:	rak (medicina), tumorske celice, mikrovezikli, biologija celice

Nazaj