| Naslov: | Oral lichen planus : key features of etiopathogenesis, diagnosis, and management |
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| Avtorji: | ID Glavina, Ana (Avtor)
ID Zanze, Lucija (Avtor)
ID Barac, Ema (Avtor)
ID Špiljak, Bruno (Avtor)
ID Čulina, Duje (Avtor)
ID Lugović-Mihić, Liborija (Avtor) |
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| Datoteke: |  URL - Izvorni URL, za dostop obiščite https://acta-apa.mf.uni-lj.si/journals/acta-dermatovenerol-apa/papers/10.15570/actaapa.2025.21/actaapa.2025.21.pdf
 PDF - Predstavitvena datoteka, prenos (15,18 MB)
MD5: 070FBFBEC517C09820AB66FFE1259510
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| Jezik: | Angleški jezik |
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| Tipologija: | 1.02 - Pregledni znanstveni članek |
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| Organizacija: |  ZSD - Združenje slovenskih dermatovenerologov
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| Povzetek: | Oral lichen planus (OLP) is a chronic inflammatory autoimmune disease of unknown etiology. It is assumed that a genetic predisposition contributes to the development of the disease and influences the patient’s response to various etiological factors such as autoimmune reactions to epithelial antigens, microorganisms, and stress. Immunopathogenesis is primarily driven by cellmediated immune mechanisms, with T lymphocytes playing a central role. The clinical presentation of OLP is varied, and multiple clinical forms can occur in the same patient. OLP is categorized into six clinical types: reticular, papular, and plaque-like (hyperkeratotic variants), and atrophic, erosive, and bullous (erosive variants). The histopathological diagnosis of OLP is unique. Continuous follow-up of patients is crucial because OLP is considered an oral potentially malignant disorder (OPMD). Reported rates of malignant transformation vary, with a pooled estimate of 1.43% for OLP and 5.13% for OLP with dysplasia. Patient education plays a crucial role in treatment initiation and planning. A personalized treatment approach focuses on controlling inflammation and relieving symptoms such as pain and burning. Treatment should be individualized according to disease severity, subtype, and patient response, with constant monitoring for possible malignant transformation and comorbidities. |
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| Ključne besede: | etiopathogenesis, clinical features, malignant transformation, oral lichen planus, treatment |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Poslano v recenzijo: | 12.05.2025 |
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| Datum sprejetja članka: | 17.07.2025 |
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| Datum objave: | 01.09.2025 |
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| Kraj izida: | Ljubljana |
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| Založnik: | Združenje slovenskih dermatovenerologov |
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| Leto izida: | 2025 |
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| Št. strani: | str. 109-115 |
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| Številčenje: | Vol. 34, issue 3 |
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| PID: | 20.500.12556/DiRROS-29906  |
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| UDK: | 616.5:579 |
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| ISSN pri članku: | 1318-4458 |
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| DOI: | 10.15570/actaapa.2025.21 |
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| COBISS.SI-ID: | 260285443 |
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| Avtorske pravice: | Na spletni strani revije navedeno: Acta Dermatovenerologica Alpina, Pannonica et Adriatica (ISSN 1318-4458) is an open access medical journal published quarterly by the Association of Slovenian Dermatovenerologists (https://acta-apa.mf.uni-lj.si/index.php); Authors publishing in our journal retain copyright of their work under the Creative Commons Attribution License (CC BY 4.0). This license allows unrestricted use, distribution, and reproduction of the work in any medium, provided the original author(s) and copyright holder(s) are appropriately credited, and the original publication in the journal is properly cited, following established academic practices (https://acta-apa.mf.uni-lj.si/submissions.php). |
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| Datum objave v DiRROS: | 15.06.2026 |
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| Število ogledov: | 236 |
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| Število prenosov: | 184 |
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| Metapodatki: |    |
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