| Naslov: | Clinical characteristics and outcomes of tympanomastoid paragangliomas : a report from Slovenia |
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| Avtorji: | ID Hribar, Manja (Avtor)
ID Fošnarič, Iztok (Avtor)
ID Matos, Aleš (Avtor)
ID Šifrer, Robert (Avtor)
ID Grošelj, Aleš (Avtor)
ID Debeljak, Maruša (Avtor)
ID Zidar, Nina (Avtor)
ID Strojan, Primož (Avtor)
ID Jenko, Klemen (Avtor) |
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| Datoteke: |  PDF - Predstavitvena datoteka, prenos (6,93 MB)
MD5: 13BE54F84D4A799B6C2DF0FAA530602F
 URL - Izvorni URL, za dostop obiščite https://www.mdpi.com/2072-6694/16/18/3178
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| Jezik: | Angleški jezik |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: |  UKC LJ - Univerzitetni klinični center Ljubljana
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| Povzetek: | Background: Head and neck paragangliomas are neuroendocrine tumors that typically originate from the parasympathetic nervous system and are predominantly non-secretory. Their clinical manifestations result from their mass effect on the surrounding tissues. The approach to treating these tumors depends on factors such as their location, size, impact on adjacent structures, and the patient’s overall health and preferences. (2) Methods: A retrospective analysis of the management of temporal bone paraganglioma classes A and B (according to the modified Fisch classification) was performed at the University Medical Centre, Ljubljana, between 2011 and 2023. (3) Results: We analyzed 23 cases, 19 of which underwent surgery; complete tumor removal was achieved in 18 of them. Four patients were irradiated due to tumor progression to class C. Three of these four patients initially refused surgery and were treated with radiotherapy (RT) 7, 13, and 18 years after diagnosis. In the fourth patient, complete surgical resection was not achieved and she was treated with RT four years after surgery, due to the growth of the tumor to class C. The average follow-up time from diagnosis was 8.9 years (median 6 years; range 1–26 years). (4) Conclusions: The surgical treatment of patients with class A and B paragangliomas is effective and safe. In cases where surgery is refused but the tumor continues to grow to class C, RT is an alternative and efficient method of controlling tumor growth. |
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| Ključne besede: | paraganglioma, jugulotympanic, tympanic, treatment |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Leto izida: | 2024 |
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| Št. strani: | str. 1-12 |
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| Številčenje: | Vol. 16, no. 18; ǂ[article no.] ǂ3178 |
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| PID: | 20.500.12556/DiRROS-29757  |
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| UDK: | 616-006 |
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| ISSN pri članku: | 2072-6694 |
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| DOI: | 10.3390/cancers16183178 |
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| COBISS.SI-ID: | 209370371 |
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| Opomba: | Nasl. z nasl. zaslona;
Opis vira z dne 29. 9. 2024;
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| Datum objave v DiRROS: | 04.06.2026 |
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| Število ogledov: | 33 |
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| Število prenosov: | 14 |
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| Metapodatki: |    |
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