| Naslov: | Aminoglycoside antibiotics as first-line treatment of acute appendicitis and cholecystitis |
|---|
| Avtorji: | ID Šetinc, Lučka (Avtor)
ID Pintar, Tadeja (Avtor)
ID Zafirovski, Aleksandar (Avtor)
ID Godnov, Uroš (Avtor)
ID Beović, Bojana (Avtor) |
|---|
| Datoteke: |  PDF - Predstavitvena datoteka, prenos (1,30 MB)
MD5: 1AA2C4CFCC4A87B38F15CBE10DBDF178
 URL - Izvorni URL, za dostop obiščite https://www.tandfonline.com/doi/epdf/10.1080/1120009X.2024.2381158?needAccess=true
|
|---|
| Jezik: | Angleški jezik |
|---|
| Tipologija: | 1.01 - Izvirni znanstveni članek |
|---|
| Organizacija: |  UKC LJ - Univerzitetni klinični center Ljubljana
|
|---|
| Povzetek: | We analyzed the efficacy and safety of aminoglycosides in a retrospective study of 415 patients with acute appendicitis and 277 patients with acute cholecystitis. The following variables increased the incidence of postoperative complications, defined as surgical site infection, recurrent intraabdominal infection, non-infectious post-operative complication, or death: age (p = 0.016 and 0.011), kidney disease (p = 0.019 and <0.001), and ASA Score (p < 0.001). The type of antibiotic therapy did not have a statistically significant effect on the incidence of postoperative complications in patients with acute appendicitis and cholecystitis (p = 0.561 and 0.547, respectively). A linear regression model showed a higher complication rate in patients with kidney disease (p = 0.014) and neoplasms (p = 0.013); the type of antibiotic therapy did not have a significant effect on the outcome (p = 0.765). There was no statistically significant difference in the post-treatment levels of creatinine in patients treated with aminoglycosides (gentamicin 3 mg/kg once daily) and in those who received other antibiotics (p = 0.75). |
|---|
| Ključne besede: | aminoglycoside, antibiotics, antimicrobial resistance, intraabdominal infection, nephrotoxicity, risk factors |
|---|
| Status publikacije: | Objavljeno |
|---|
| Verzija publikacije: | Objavljena publikacija |
|---|
| Leto izida: | 2025 |
|---|
| Št. strani: | str. 307-316 |
|---|
| Številčenje: | Vol. 37, iss. 4 |
|---|
| PID: | 20.500.12556/DiRROS-28634  |
|---|
| UDK: | 616-07 |
|---|
| ISSN pri članku: | 1973-9478 |
|---|
| DOI: | 10.1080/1120009X.2024.2381158 |
|---|
| COBISS.SI-ID: | 203877379 |
|---|
| Opomba: | Nasl. z nasl. zaslona;
Opis vira z dne 8. 8. 2024;
|
|---|
| Datum objave v DiRROS: | 26.03.2026 |
|---|
| Število ogledov: | 179 |
|---|
| Število prenosov: | 114 |
|---|
| Metapodatki: |    |
|---|
|
:
|
Kopiraj citat |
|---|
| | | | Objavi na: |  |
|---|
Postavite miškin kazalec na naslov za izpis povzetka. Klik na naslov izpiše
podrobnosti ali sproži prenos. |
