| Naslov: | Adipose tissue transcriptome profiles of local Krškopolje pig and modern hybrid pigs receving reduced protein diets: : expression profiling by high throughput sequencing |
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| Avtorji: | ID Poklukar Žnidaršič, Klavdija (Avtor)
ID Škrlep, Martin (Avtor)
ID Čandek-Potokar, Marjeta (Avtor) |
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| Datoteke: |  URL - Izvorni URL, za dostop obiščite https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE309090
Opis: Podatki nedostopni, 7. 10. 2025, dostopni po 24. 9. 2029
 PDF - Predstavitvena datoteka. (481,38 KB, Vsebina dokumenta nedostopna do 24.09.2029)
MD5: 49DF1579FA25210FE0E9DCF2986A2DCD
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| Jezik: | Angleški jezik |
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| Tipologija: | 2.20 - Zaključena znanstvena zbirka raziskovalnih podatkov |
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| Organizacija: |  KIS - Kmetijski inštitut Slovenije
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| Povzetek: | The main objective of this study was to investigate transcriptomic differences in subcutaneous adipose tissue between the local Krškopolje pig and modern hybrids, and to assess the effects of a reduced-protein diet in both genotypes. Comparative analysis between Krškopolje pigs and modern crossbreeds revealed 375 differentially expressed genes, with 189 upregulated and 186 downregulated in Krškopolje pigs. The upregulated genes were enriched in processes related to adipogenesis (SLC7A10, ADIRF, INHBB, SFRP2), extracellular matrix remodeling (COL6A5, COL4A5, COL2A1), calcium signaling (TRPV4, CAMK2A, CALML5), pro-inflammatory cytokines (IL1A, TNFSF9, CXCL8, PTGS2), and cholesterol metabolism (CYP1A1, CYP2A19, CES1). In contrast, the reduced-protein diet induced only minor transcriptional changes at the individual gene level in both Krškopolje pigs and modern crossbreeds. |
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| Ključne besede: | RNA sequences, pigs, adipose tissue, high throughput sequencing, RNA, transcriptome profiles, gene expression, locel breeds, hybrid breeds, data, data set |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Datum objave: | 24.09.2025 |
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| Kraj izida: | Bethesda |
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| Kraj izvedbe: | Bethesda |
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| Založnik: | Gene Expression Omnibus (GEO) |
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| Leto izida: | 2025 |
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| Leto izvedbe: | 2025 |
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| Št. strani: | 1 spletni vir |
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| PID: | 20.500.12556/DiRROS-28462  |
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| UDK: | 636 |
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| COBISS.SI-ID: | 252017667 |
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| Opomba: | Nasl. z. nasl. zaslona;
Opis vira z dne 7. 10. 2025;
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| Datum objave v DiRROS: | 20.03.2026 |
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| Število ogledov: | 258 |
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| Število prenosov: | 48 |
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| Metapodatki: |    |
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