| Naslov: | A chromosome-level genome assembly of the western nose-horned viper (Vipera ammodytes ammodytes) |
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| Avtorji: | ID Rao, Weiqiao (Avtor)
ID Rivera-de-Torre, Esperanza (Avtor)
ID Seneci, Lorenzo (Avtor)
ID Pungerčar, Jože, Institut "Jožef Stefan" (Avtor)
ID Hougaard Laustsen, Andreas (Avtor), et al. |
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| Datoteke: |  URL - Izvorni URL, za dostop obiščite https://academic.oup.com/gbe/article/17/12/evaf210/8317694
 PDF - Predstavitvena datoteka, prenos (568,88 KB)
MD5: A3D9B1DFDBCAFFA3EEB775FB7AD8A3E0
Opis: The raw sequencing data and assembled genomes that support the findings of this study have been deposited into the CNGB Sequence Archive (CNSA) (Guo et al. 2020) of the China National GenBank Database (CNGBdb) (Chen et al. 2020), https://db.cngb.org/cnsa/ with accession number CNP0002260, and into NCBI with the BioProject ID PRJNA1177245.
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| Jezik: | Angleški jezik |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: |  IJS - Institut Jožef Stefan
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| Povzetek: | We present a chromosome-level genome assembly of the western nose-horned viper (Vipera ammodytes ammodytes), the most medically important viper in Europe. Using PacBio Sequel and Illumina HiSeq X Ten sequencing, we generated ∼270 Gb of data, achieving ∼131× coverage of the genome. The final assembly spans 1.55 Gb with a contig N50 of 45.9 Mb and a scaffold N50 of 210 Mb, anchored into 18 pseudo-chromosomes. Completeness was supported by recovery of 97.1% of Vertebrata BUSCOs. A total of 20,775 protein-coding genes were predicted, of which 96.6% were functionally annotated. Repetitive sequences accounted for 53.75% of the genome, dominated by LINEs (41.87%) and LTRs (14.35%). We identified 112 venom-related genes across 15 families, with expansions in SVMPs, Snaclecs, sPLA₂s, SPIs, and SVSPs, together comprising 62.5% of the venom repertoire. Chemosensory genes were also expanded, including 448 olfactory receptors, 72 taste receptors, and 29 vomeronasal receptors. This assembly represents the most complete genome resource for a true viper to date and provides a key resource for investigating venom evolution, chemosensory adaptation, and comparative snake genomics. |
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| Ključne besede: | snake venom, venom gland |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Datum sprejetja članka: | 31.10.2025 |
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| Datum objave: | 10.11.2025 |
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| Založnik: | Oxford University Press |
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| Leto izida: | 2025 |
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| Št. strani: | str. 1-7 |
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| Številčenje: | Vol. 17, iss. 12 |
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| Izvor: | Združeno kraljestvo |
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| PID: | 20.500.12556/DiRROS-27496  |
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| UDK: | 575.111 |
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| ISSN pri članku: | 1759-6653 |
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| DOI: | 10.1093/gbe/evaf210 |
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| COBISS.SI-ID: | 267892995 |
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| Avtorske pravice: | © The Author(s) 2025. |
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| Opomba: | Nasl. z nasl. zaslona;
Opis vira z dne 10. 2. 2026;
Soavtor iz Slovenije: Jože Pungerčar;
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| Datum objave v DiRROS: | 10.02.2026 |
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| Število ogledov: | 521 |
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| Število prenosov: | 217 |
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| Metapodatki: |    |
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