| Naslov: | Functionality of potato virus Y coat protein in cell-to-cell movement dynamics is defined by its N-terminal region |
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| Avtorji: | ID Vozelj, Anže (Avtor)
ID Mahkovec Povalej, Tjaša (Avtor)
ID Stare, Katja (Avtor)
ID Tušek-Žnidarič, Magda (Avtor)
ID Bačnik, Katarina (Avtor)
ID Levak, Valentina (Avtor)
ID Gutiérrez-Aguirre, Ion (Avtor)
ID Podobnik, Marjetka (Avtor)
ID Gruden, Kristina (Avtor)
ID Coll Rius, Anna (Avtor)
ID Lukan, Tjaša (Avtor) |
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| Datoteke: |  URL - Izvorni URL, za dostop obiščite https://doi.org/10.1128/jvi.01400-25
 PDF - Predstavitvena datoteka, prenos (1,50 MB)
MD5: 976F9C5F819C4D96622A46E2D216CAA8
PDF - Predstavitvena datoteka, prenos (4,12 MB)
MD5: 61F8064D4BCA20EB9E93511D4E863A74
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| Jezik: | Angleški jezik |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: |  NIB - Nacionalni inštitut za biologijo
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| Povzetek: | Potato virus Y (PVY) is one of the top 10 economically most important plant viruses and responsible for major yield losses. We previously suggested the involvement of the N-terminal region of PVY coat protein (CP) in PVY spread. By constructing different N-terminal deletion mutants of the PVY N605 strain, we here show that deletions of 40 or more amino acid residues from the N-terminal region of the CP resulted in the PVY multiplication limited to primary infected cells in Nicotiana clevelandii plants. Deletion of 26 residues profoundly impaired PVY cell-to-cell movement and prevented systemic PVY spread, while deletions of 19-23 residues allowed delayed systemic PVY spread. Introduced point mutations in the identified region prevent (S21G) or delay (G20P) PVY movement. In summary, this work shows the significance of the CP N-terminus for movement of the PVY. |
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| Ključne besede: | potato virus Y, potato, coat proteins, viral movement, point mutations |
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| Status publikacije: | V tisku |
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| Verzija publikacije: | Recenzirani rokopis |
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| Datum objave: | 20.11.2025 |
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| Leto izida: | 2025 |
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| PID: | 20.500.12556/DiRROS-24784  |
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| UDK: | 577.2 |
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| ISSN pri članku: | 1098-5514 |
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| DOI: | 10.1128/jvi.01400-25 |
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| COBISS.SI-ID: | 259503619 |
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| Opomba: | Nasl. z nasl. zaslona;
Soavtorji: Tjaša Mahkovec Povalej, Katja Stare, Magda Tušek Žnidarič, Katarina Bačnik, Valentina Levak, Ion Gutiérrez-Aguirre, Marjetka Podobnik, Kristina Gruden, Anna Coll, Tjaša Lukan;
Članek v PDF formatu obsega 14 str.;
Opis vira z dne 2. 12. 2025;
Online first: 20. Nov. 2025;
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| Datum objave v DiRROS: | 18.12.2025 |
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| Število ogledov: | 57 |
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| Število prenosov: | 58 |
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| Metapodatki: |    |
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