| Naslov: | Erythema migrans in patients with post-traumatic splenectomy |
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| Avtorji: | ID Maraspin-Čarman, Vera (Avtor)
ID Ogrinc, Katarina (Avtor)
ID Bogovič, Petra (Avtor)
ID Rojko, Tereza (Avtor)
ID Ružić-Sabljić, Eva (Avtor)
ID Wormser, Gary P. (Avtor)
ID Strle, Franc (Avtor) |
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| Datoteke: |  PDF - Predstavitvena datoteka, prenos (514,76 KB)
MD5: 9B9F07506D95E5223A207E535BE7C0BD
 URL - Izvorni URL, za dostop obiščite https://www.mdpi.com/2076-2607/12/7/1465
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| Jezik: | Angleški jezik |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: |  UKC LJ - Univerzitetni klinični center Ljubljana
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| Povzetek: | Information on asplenic Lyme borreliosis (LB) patients with erythema migrans (EM) is lacking. We compared the course and outcome of 26 EM episodes in 24 post-trauma splenectomized patients (median age 51 years) diagnosed at a single clinical center in Slovenia during 1994–2023 with those of 52 age- and sex-matched patients with EM but with no history of splenectomy. All patients were followed for one year. A comparison of pre-treatment characteristics revealed that EM in splenectomized patients was of shorter duration before diagnosis (4 vs. 8 days, p = 0.034) with a smaller EM diameter (10.5 vs. 14 cm, p = 0.046), and more frequently fulfilled criteria for disseminated LB (3/26, 11.5% vs. 0%, p = 0.034). Treatment failure occurred in 5/26 (19.2%) EM episodes in splenectomized patients versus 0/52 in non-splenectomized patients (p = 0.003). The five treatment failure cases were retreated with antibiotic regimens used to treat EM and had complete resolution of all symptoms/signs. In conclusion, our study showed that splenectomized adult patients with EM differ somewhat in presentation and more often have treatment failure compared with non-splenectomized patients with EM. |
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| Ključne besede: | erythema migrans, Lyme borreliosis, Lyme disease |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Leto izida: | 2024 |
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| Št. strani: | str. 1-14 |
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| Številčenje: | Vol. 12, iss. 7, [article no.] 1465 |
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| PID: | 20.500.12556/DiRROS-24579  |
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| UDK: | 616.9:579 |
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| ISSN pri članku: | 2076-2607 |
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| DOI: | 10.3390/microorganisms12071465 |
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| COBISS.SI-ID: | 217710595 |
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| Opomba: | Nasl. z nasl. zaslona;
Opis vira z dne 4. 12. 2024;
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| Datum objave v DiRROS: | 08.12.2025 |
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| Število ogledov: | 75 |
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| Število prenosov: | 41 |
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| Metapodatki: |    |
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