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Naslov:Interval cancers after negative immunochemical test compared to screen and non-respondersʼ detected cancers in Slovenian colorectal cancer screening programme
Avtorji:ID Novak-Mlakar, Dominika (Avtor)
ID Kofol-Bric, Tatjana (Avtor)
ID Škrjanec, Ana Lucija (Avtor)
ID Krajc, Mateja (Avtor)
Datoteke:.pdf PDF - Predstavitvena datoteka, prenos (288,68 KB)
MD5: 529DFA8C25AAE844CE1360C47473D91F
 
Jezik:Angleški jezik
Tipologija:1.01 - Izvirni znanstveni članek
Organizacija:Logo OI - Onkološki inštitut Ljubljana
Povzetek:We assessed the incidence and characteristics of interval cancers after faecal immunochemical occult blood test and calculated the test sensitivity in Slovenian colorectal cancer screening programme. Patients and methods. The analysis included the population aged between 50 to 69 years, which was invited for screening between April 2011 and December 2012. The persons were followed-up until the next foreseen invitation, in average for 2 years. The data on interval cancers and cancers in non-responders were obtained from cancer registry. Gender, age, years of schooling, the cancer site and stage were compared among three observed groups. We used the proportional incidence method to calculate the screening test sensitivity. Results. Among 502,488 persons invited for screening, 493 cancers were detected after positive screening test, 79 interval cancers after negative faecal immunochemical test and 395 in non-responders. The proportion of interval cancers was 13.8%. Among the three observed groups cancers were more frequent in men (p = 0.009) and in persons aged 60+ years (p < 0.001). Comparing screen detected and cancers in non-responders with interval cancers more interval cancers were detected in persons with 10 years of schooling or more (p = 0.029 and p = 0.001), in stage III (p = 0.027) and IV (p < 0.001), and in right hemicolon (p < 0.001). Interval cancers were more frequently in stage I than non-responders cancers (p = 0.004). Test sensitivity of faecal immunochemical test was 88.45%. Conclusions. Interval cancers in Slovenian screening programme were detected in expected proportions as in similar programmes. Test sensitivity was among the highest when compared to similar programmes and was accomplished using test kit for two stool samples.
Ključne besede:cancer screening, colorectal cancer, faecal immunochemical test, test sensitivity
Status publikacije:Objavljeno
Verzija publikacije:Objavljena publikacija
Datum objave:01.12.2018
Založnik:Association of Radiology and Oncology
Leto izida:2018
Št. strani:str. 413-421, V
Številčenje:Vol. 52, no. 4
Izvor:Ljubljana
PID:20.500.12556/DiRROS-19078 Novo okno
UDK:614
ISSN pri članku:1318-2099
DOI:10.2478/raon-2018-0025 Novo okno
COBISS.SI-ID:2983803 Novo okno
Avtorske pravice:by Authors
Datum objave v DiRROS:10.06.2024
Število ogledov:61
Število prenosov:21
Metapodatki:XML RDF-CHPDL DC-XML DC-RDF
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Gradivo je del revije

Naslov:Radiology and oncology
Skrajšan naslov:Radiol. oncol.
Založnik:Slovenian Medical Society - Section of Radiology, Croatian Medical Association - Croatian Society of Radiology
ISSN:1318-2099
COBISS.SI-ID:32649472 Novo okno

Sekundarni jezik

Jezik:Slovenski jezik
Ključne besede:presejalni programi, rak debelega črevesa, fekalni imunokemični testi, kolorektalni rak


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