| Naslov: | Clinical significance of histologic subtyping of malignant pleural mesothelioma |
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| Avtorji: | ID Brčić, Luka (Avtor)
ID Kern, Izidor, Klinika Golnik (Avtor) |
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| Datoteke: |  PDF - Predstavitvena datoteka, prenos (1,86 MB)
MD5: 7FB5E9D004DA51FE3C51F4D3271B9B52
 URL - Izvorni URL, za dostop obiščite http://tlcr.amegroups.com/article/view/38662/pdf
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| Jezik: | Angleški jezik |
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| Tipologija: | 1.02 - Pregledni znanstveni članek |
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| Organizacija: |  UKPBAG - Univerzitetna klinika za pljučne bolezni in alergijo Golnik
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| Povzetek: | Malignant mesothelioma (MM) is uncommon, but very aggressive tumor arising from the mesothelial cells of pleura, pericardium, peritoneum, and tunica vaginalis. Despite multimodality treatments 5-year survival is only 5% after the diagnosis. Histology and TNM staging system are still the best prognostic factors. Furthermore, histologic subtype of MM determines the clinical management of the patients. According to the 2015 WHO classification, MM is divided into diffuse, localized and well differentiated papillary mesothelioma. Major histologic subtypes of diffuse MM, namely epithelioid, biphasic and sarcomatoid, have different prognosis. However, in the last decade it has become evident that more detailed subclassification and histologic/cytological characterization of MM have prognostic and perhaps predictive implications. In this review, major histologic subtypes and cytological features of MM are presented and their relation with prognosis and predictive biomarkers is discussed. |
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| Ključne besede: | malignant mesothelioma, epithelioid malignant mesothelioma, biphasic malignant mesothelioma, sarcomatoid malignant mesothelioma |
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| Status publikacije: | V tisku |
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| Verzija publikacije: | Recenzirani rokopis |
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| Kraj izida: | Hong Kong |
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| Založnik: | AME Publishing Company |
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| Leto izida: | 2020 |
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| Št. strani: | str.1-10 |
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| Številčenje: | Vol. 9, iss. |
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| PID: | 20.500.12556/DiRROS-12161  |
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| UDK: | 616-006 |
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| ISSN pri članku: | 2226-4477 |
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| DOI: | 10.21037/tlcr.2020.03.38 |
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| COBISS.SI-ID: | 17124867 |
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| Avtorske pravice: | Translational lung cancer research |
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| Opomba: | Nasl. z nasl. zaslona;
Opis vira z dne 27. 5. 2020;
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| Datum objave v DiRROS: | 22.06.2020 |
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| Število ogledov: | 2660 |
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| Število prenosov: | 1403 |
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| Metapodatki: |    |
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