20.500.12556/DiRROS-12161
Clinical significance of histologic subtyping of malignant pleural mesothelioma
Malignant mesothelioma (MM) is uncommon, but very aggressive tumor arising from the mesothelial cells of pleura, pericardium, peritoneum, and tunica vaginalis. Despite multimodality treatments 5-year survival is only 5% after the diagnosis. Histology and TNM staging system are still the best prognostic factors. Furthermore, histologic subtype of MM determines the clinical management of the patients. According to the 2015 WHO classification, MM is divided into diffuse, localized and well differentiated papillary mesothelioma. Major histologic subtypes of diffuse MM, namely epithelioid, biphasic and sarcomatoid, have different prognosis. However, in the last decade it has become evident that more detailed subclassification and histologic/cytological characterization of MM have prognostic and perhaps predictive implications. In this review, major histologic subtypes and cytological features of MM are presented and their relation with prognosis and predictive biomarkers is discussed.
malignant mesothelioma
epithelioid malignant mesothelioma
biphasic malignant mesothelioma
sarcomatoid malignant mesothelioma
maligni mezoteliom
epiteloidni maligni mezoteliom
bifazni maligni mezoteliom
sarkomatoidni maligni mezoteliom
true
false
true
AME Publishing Company
Angleški jezik
Ni določen
http://tlcr.amegroups.com/article/view/38662
Translational lung cancer research
Neznano
2020-06-22 12:48:20
2020-06-22 12:55:59
2022-08-18 03:35:34
0000-00-00 00:00:00
2020
0
Hong Kong
0
Nasl. z nasl. zaslona;
Opis vira z dne 27. 5. 2020;
str.1-10
iss.
Vol. 9
2020
0000-00-00
PostprintKoncna
VTisku
NiDoloceno
0000-00-00
0000-00-00
0000-00-00
0000-00-00
616-006
2226-4477
10.21037/tlcr.2020.03.38
17124867
17120003
RAZ_Brcic_Luka_i2020.pdf
RAZ_Brcic_Luka_i2020.pdf
1
7FB5E9D004DA51FE3C51F4D3271B9B52
162ec27bbfa8fdd84f24bf28ec31170575e2fa855de61f70b294846d1e59a7fd
8fbfb9e6-17b6-11ed-b6b8-001a4af901a5
https://dirros.openscience.si/Dokument.php?lang=slv&id=17340
http://tlcr.amegroups.com/article/view/38662/pdf
1
https://dirros.openscience.si/Dokument.php?lang=slv&id=14535
Univerzitetna klinika za pljučne bolezni in alergijo Golnik
0
0
0