1. Data in diabetic foot care : from current state to a management framework for implementationIztok Štotl, 2025, pregledni znanstveni članek Povzetek: Background/Objectives: The healthcare data sector is experiencing unprecedented growth, fueled by advances in genomics, medical imaging, and wearable devices. The convergence of universal data standards now provides the common ground needed to translate this data into medical advances. However, a significant implementation gap persists, preventing effective deployment in routine clinical practice, particularly in specialized areas like diabetic foot care. Methods: This paper examines the opportunities presented by modern data methodologies to bridge this gap, contextualized within diabetic foot care, where the paramount goals are patient well-being, tissue preservation, and amputation prevention. Results: The analysis indicates that the synergy of interoperable data and advanced management tools is poised to fundamentally transform healthcare delivery. Interdisciplinary collaboration is identified as the foundational element enabling the timely, coordinated, and evidence-based interventions necessary to achieve critical clinical objectives. Conclusions: The pivotal challenge has shifted from technological capability to effective implementation. Leveraging modern data methodologies is essential for translating potential into tangible improvements in diabetic foot outcomes. In this context, collaborative data management must be recognized as a critical treatment modality itself. Here, “data is tissue”; it must be managed with the same urgency and care to enable success.
Ključne besede: diabetes, diabetic foot, electronic health record, governance, prediction models, digital practice guidelines, guidelines definition language, diabetes registries, fair, quality of care
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2. Razvoj lesenega otroškega pripomočka za spodbujanje grobih motoričnih spretnosti po pedagogiki MontessoriKlemen Kotnik, Gorazd Fajdiga, 2025, izvirni znanstveni članek Ključne besede: Montessori, groba motorika, leseni pripomočki, otroci, numerična analiza, prototip, preskušanje
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3. Prevedba ocen kakovosti stoječih dreves na izbranih objektih v sortimentno strukturoLuka Krajnc, Janez Zafran, 2025, izvirni znanstveni članek Povzetek: V raziskavi je bila predstavljena in preračunana ocena kakovosti stoječih dreves v sortimentno strukturo. Na 123 drevesih štirih drevesnih vrst je bila opravljena primerjava med dejansko sortimentacijo po poseku in računsko sortimentacijo na osnovi predhodno ocenjene kakovosti. Izmerili smo 869 gozdno-lesnih sortimentov ter primerjali rezultate računske in dejanske sortimentacije. Rezultati so pokazali dobro ujemanje pri smreki, nekoliko manj pa pri listavcih, kjer je bil večji vpliv notranjih napak na sortimentno sestavo. Metoda je praktično uporabna in daje uporabne rezultate za napoved sortimentne sestave. Izboljšati je treba še modele napovedi velikosti grč, s čimer bi natančnost napovedi še dodatno povečali.
Ključne besede: sortimentacija, ocena kakovosti, stoječa drevesa, gozdni lesni sortimenti, iglavci, listavci, grče, računsko krojenje, notranje napake lesa, prostorninska struktura
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4. Induction of labor after fetal demise in third trimester : a retrospective cohort studySara Vodopivec, Gorazd Kavšek, Polona Pečlin, Mirjam Druškovič, 2025, izvirni znanstveni članek Povzetek: Objectives: The aim of our study was to assess the efficacy and safety of two different labor induction methods in patients after fetal demise beyond 28 weeks, with an unfavorable cervix: misoprostol—prostaglandin E1 analog (PGE1) and dinoprostone—prostaglandin E2 analog (PGE2). Methods: This retrospective single-center cohort study included all labor cases after fetal demise (intrauterine fetal death or termination of pregnancy with feticide) from 28 to 40 weeks of gestation, where labor was induced by either PGE1 or PGE2. The primary outcome was the induction-to-delivery time interval. Secondary outcomes included the proportion of patients who delivered within 24 h, the failed induction rate, the length of labor, pain during induction, the adverse outcome rate, and the post-labor hospital stay. Results: The induction-to-delivery time interval was shorter in the PGE1 group (p = 0.048). There was no statistically significant difference in the proportion of patients who delivered within 24 h (p = 0.651) and failed inductions (p = 0.18) between groups. The duration of labor was longer in the PGE2 group (p = 0.01). Oxytocin augmentation was more common in the PGE2 group (p < 0.001). Pain during induction was greater in women in the PGE1 group (p < 0.001). There were no statistically significant differences in adverse effects between groups. There was no significant difference in induction to delivery interval between the two methods when comparing lower and higher gestational ages (28 to 34 weeks, p = 0.18; 35 to 40 weeks, p = 0.343). Conclusions: Our findings support the use of a PGE1 regimen for third-trimester labor induction after fetal demise, when no contraindications exist. This approach appears to improve the efficiency of induction and may enhance overall patient care by reducing intervention needs.
Ključne besede: misoprostol, dinoprostone, fetal demise, stillbirth, termination of pregnancy beyond 28 weeks, labor induction
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5. Precipitacija v vodi netopnih bakrovih soli v lesu kot zaščita pred glivami razkrojevalkami lesaJaka Levanič, Jure Švikart, Eli Keržič, Miha Humar, 2025, izvirni znanstveni članek Povzetek: V raziskavi predstavljamo metodo zaščite lesa pred glivnim razkrojem s precipitacijo netopnih bakrovih soli v lumnih lesnih celic z uporabo dvostopenjske impregnacije s topnim bakrovim sulfatom in fiksativom, natrijevim karbonatom. Fiksacija z natrijevim karbonatom se je izkazala kot učinkovita metoda za zmanjšanje izpiranja bakra iz vzorcev. Naravna kapaciteta zadrževanja bakra v beljavi bora je okoli 2000 ppm, kar smo določili z izpiranjem po metodi SIST EN 84. S fiksacijo smo uspešno zadržali v povprečju več kot 5000 ppm bakra v vzorcih in praktično preprečili izpiranje bakra iz vzorcev, impregniranih z 0,5-odstotno raztopino bakrovega sulfata (0,5 % ustreza koncentraciji bakrovih ionov v raztopini). Kljub zadostni koncentraci- ji se je pokazalo, da precipitirana oblika bakrovega karbonata v lesu ne deluje kot učinkovit fungicid, kar je verjetno posledica izjemno slabe topnosti v vodi, ki znaša < 0,005 g/L v sobnih razmerah. Izgube mase po testu SIST EN 113-1 kažejo na slabo zaščito pred gobo Coniophora puteana, vendar na zadovoljivo zaščito pred gobo Gloeophyllum trabeum.
Ključne besede: zaščita lesa, bakrovi biocidi, fiksacija bakra, glivni razkroj
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6. Izbira tehnologije strojne sečnje in spravila lesa na strmih terenihLuka Pajek, Janez Krč, 2025, izvirni znanstveni članek Povzetek: Zaradi potrebe po vse večji humanizaciji dela in vsesplošnem pomanjkanju delavcev, se povečuje delež strojne sečnje in spravila lesa tudi na strmih terenih. Analizirali smo možnost uporabe različnih tehnoloških rešitev za delo na strmih terenih. Nabor in vrednotenje tehnoloških rešitev smo povzeli po nemški raziskavi (Findeisen, 2008). Na podlagi primerjave razpoložljivih modelov tehnoloških rešitev smo v prvi fazi izmed 19 izbrali pet modelov: 1) stroj za sečnjo in zgibni polprikoličar, 2) stroj za sečnjo z gosenicami in zgibni polprikoličar z vitlom za povečanje oprijema, 3) model z motorno žago, strojem za sečnjo z gosenicami in zgibni polprikoličar z vitlom za povečanje oprijema, 4) model v kombinaciji žičnice in motorne žage ter 5) sedlasti traktor s procesorsko glavo. Dodali smo še model 6) model z motorno žago, strojem za sečnjo z vitlom za povečanje oprijema in zgibni polprikoličar z vitlom za povečanje oprijema, ker je bil v preteklosti že uporabljen na izbranem delovišču. Glede na razmere na konkretnem delovišču smo izbranim modelom prve faze ocenili njihovo primernost po treh vidikih (ergonomski, okoljski in ekonomski). Za izbrane modele smo izračunali strošek dela, kjer smo upoštevali popravke cene dela, ki izhajajo iz razmer za izvedbo del na delovišču. Rezultati so pokazali, da je za analizirano delovišče najprimernejši model 6, ki omogoča sečnjo debelih dreves na velikih naklonih in izvedbo del na vsej površini delovišča. Medsebojna primerjava različnih tehnoloških rešitev in posledično izbor najbolj primernega tehnološkega modela v danih razmerah je sicer pilotna, a jo ocenjujemo kot koristno pomoč pri načrtnem in uspešnem uvajanju sodobnih tehnologij v slovensko gozdarstvo.
Ključne besede: strojna sečnja, spravilo lesa, vitel za povečanje oprijema, strmi tereni, ergonomski vpliv, okoljski vpliv
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7. Rare Basidiomycete resupinatus rouxii reported for the first time in Türki̇yeIsmail Acar, Halide Karabiyik, 2025, izvirni znanstveni članek Povzetek: In this study, Resupinatus rouxii Consiglio & Setti was collected from Çanakkale province, Türkiye, and identified using both morphological and molecular data. Macroscopically, the species is characterised by its small size, kidney-shaped pileus, light grey colour, and slightly hairy surface. Microscopic examination confirmed diagnostic features of the genus Resupinatus, and detailed evaluations were made of the basidia, basidiospores, and cystidia. The internal transcribed spacer (ITS) region of nuclear ribosomal DNA was sequenced and used in phylogenetic analyses. The resulting ITS sequence showed more than 99% similarity to the reference sequence of R. rouxii, supporting the morphological identification. This study represents the second scientific report of R. rouxii worldwide and provides the fourth known record of this species, extending its known distribution to Türkiye (Çanakkale province) and contributing valuable data to its biogeography.
Ključne besede: Resupinatus, fungi, new record, internal transcribed spacer region, molecular phylogeny, Turky
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8. Exercise-induced hypertension after aortic coarctation repair : our experience and a systematic reviewPolona Kačar, Nejc Pavšič, Katja Prokšelj, 2024, izvirni znanstveni članek Povzetek: Background: The exact prevalence and clinical significance of excessive increase in blood pressure in response to exercise in patients with repaired coarctation of aorta (CoA) remains unknown.Aim: This study aimed to investigate the impact of different definitions of exercise-induced hypertension (EIH) on the prevalence rates in our adult patients with repaired CoA. A systematic review of the available literature was also performed.Methods: We retrospectively analyzed exercise test data from adult patients with repaired CoA followed at the national referral center for adult congenital heart disease between 1998 and 2021. The three most reported definitions of EIH in patients with repaired CoA were used for the analysis of EIH prevalence. We also performed a systematic search of the PubMed electronic bibliographic database. Full-text versions of all potentially relevant articles on EIH in CoA were reviewed for relevance.Results: Our registry included 161 adult CoA patients. Complete exercise test results were available in 74 patients (59% male, median age 39 years [range 20–68 years]). The prevalence of EIH in our cohort varied from 24 to 41%, depending on the definition used. We identified eleven eligible articles from 184 publications. The reported prevalence rate of EIH in the studies ranged from 13% to 82%.Conclusion: EIH is common in patients with repaired CoA; however, the rates of EIH vary greatly depending on the definition used. A standardized and uniform EIH definition is needed to accurately assess the prevalence and clinical relevance of EIH in this population.
Ključne besede: congenital heart disease, adults, aortic coarctation, exercise, hypertension
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9. ACE inhibitor and angiotensin receptor blocker use during pregnancy : data from the ESC registry of pregnancy and cardiac disease (ROPAC)Johanna A. Van der Zande, Karishma P. Ramlakhan, Katja Prokšelj, Edison Muñoz-Ortiz, Amalia Baroutidou, Magdalena Lipczynska, 2024, izvirni znanstveni članek Povzetek: Angiotensin-converting enzyme inhibitors (ACE-Is) and angiotensin receptor blockers (ARBs) are not recommended during the second and third trimester because of the significant risk of congenital anomalies associated with their use. However, data are scarce, especially regarding their use in the first trimester and about the impact of stopping just before pregnancy. Our study illustrates the profile of the women who used ACE-Is or ARBs during pregnancy and evaluates the impact on perinatal outcomes. The Registry of Pregnancy and Cardiac Disease is a prospective, global registry of pregnancies in women with structural heart disease. Outcomes were compared between women who used ACE-Is or ARBs and those who did not. Multivariable regression analysis was performed to assess the effect of ACE-I or ARB use on the occurrence of congenital anomalies. ACE-Is (n = 35) and/or ARBs (n = 8) were used in 42 (0.7%) of the 5,739 Registry of Pregnancy and Cardiac Disease pregnancies. Women who used ACE-Is or ARBs more often came from a low-or-middle-income country (57% vs 40%, p = 0.021), had chronic hypertension (31% vs 6%, p <0.001), or a left ventricular ejection fraction <40% (33% vs 4%, p <0.001). In the multivariable analysis, ACE-I use during the first trimester was associated with an increased risk of congenital anomaly (odds ratio 3.2, 95% confidence interval 1.0 to 9.6). Therefore, ACE-Is should be avoided during pregnancy, also in the first trimester, because of a higher risk of congenital anomalies. However, there is no need to stop long before pregnancy. Preconception counseling is crucial to discuss the potential risks of these medications, to evaluate the clinical condition and, if possible, to change or stop the medication.
Ključne besede: ACE inhibitor, angiotensin receptor blocker, preconception, pregnancy
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10. Quality of life in adults with congenital heart disease : insights from a tertiary centrePolona Kačar, Melita Flander, Katja Prokšelj, 2025, izvirni znanstveni članek Povzetek: Objective: As the survival of individuals born with congenital heart disease (CHD) improves into adulthood, the focus has shifted from traditional clinical outcomes to patient-reported outcome measures that better reflect the impact of the disease on daily life. Our aim was to assess the quality of life (QoL) of adult patients with congenital heart disease (ACHD) followed in a tertiary centre and to evaluate the parameters that influence QoL in this population. Methods: This cross-sectional observational study included patients followed up at the national referral ACHD centre between April and September 2022. Sociodemographic and clinical data were collected from medical records and self-report questionnaires. Quality of life (QoL) was assessed using the validated Short Form–36 (SF-36) and Euro Quality of Life–5 Dimension (EQ-5D) questionnaires, including the EQ Visual Analogue Scale (VAS). Results: A total of 123 ACHD patients were included (median age 34 (29–41) years; 43.9% male). Most participants had moderate CHD (61%), and 14.6% were cyanotic. Overall, SF-36 Physical Component Summary scores were higher than Mental Component Summary scores. Almost half of the patients (48.8%) reported no problems in all five domains of the EQ-5D, with most problems reported in anxiety/depression domain. Patients with severe CHD, cyanosis, or HF reported lower QoL scores across multiple SF-36 domains, particularly general health, role–physical, and physical functioning domains. Conclusions: QoL among ACHD patients in our cohort was generally high in most domains as assessed by the SF-36 and EQ-5D. Patients with HF reported lower QoL scores, emphasizing the importance of close clinical follow-up and the need for tailored QoL assessment tools for this complex population.
Ključne besede: adults, congenital heart disease, quality of life
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