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Naslov: Smernice za obravnavo bolnikov s skvamoznoceličnim karcinomom analnega kanala in kože perinealno (analnega roba) Avtorji: ID Oblak, Irena (Avtor) ID Velenik, Vaneja (Avtor) ID Anderluh, Franc (Avtor) ID Skoblar Vidmar, Marija (Avtor) ID But-Hadžić, Jasna (Avtor) ID Brecelj, Erik (Avtor) ID Reberšek, Martina (Avtor) ID Jelenc, Franc (Avtor) ID Potrč, Stojan (Avtor) Datoteke: PDF - Predstavitvena datoteka, prenos (309,75 KB) MD5: 5E9072FEFC972B240EF5A2475FEEA5B4 PID: 20.500.12556/dirros/2f125366-249a-4d43-a7d3-eb53eead86c9   Jezik: Slovenski jezik Tipologija: 1.04 - Strokovni članek Organizacija: OI - Onkološki inštitut Ljubljana Ključne besede: rak (medicina), debelo črevo, danka Status publikacije: Objavljeno Verzija publikacije: Objavljena publikacija Leto izida: 2013 Št. strani: str. 105-108, 154 Številčenje: Letn. 17, št. 2 PID: 20.500.12556/DiRROS-8816  UDK: 616.35-006.6-08 ISSN pri članku: 1408-1741 URN: URN:NBN:SI:doc-OE0IKK8M COBISS.SI-ID: 1651323  Avtorske pravice: by Authors Opomba: Soavtorji: V. Velenik, F. Anderluh, M. Skoblar Vidmar, J. But Hadžić, E. Brecelj, M. Reberšek, F. Jelenc, S. Potrč; Datum objave v DiRROS: 31.08.2018 Število ogledov: 3524 Število prenosov: 980 Metapodatki:    Citiraj gradivo Navadno besedilo BibTeX EndNote XML EndNote/Refer RIS ABNT ACM Ref AMA APA Chicago 17th Author-Date Harvard IEEE ISO 690 MLA Vancouver : Kopiraj citat

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Gradivo je del revije

Naslov:	Onkologija
Skrajšan naslov:	Onkologija
Založnik:	Onkološki inštitut
ISSN:	1408-1741
COBISS.SI-ID:	65324032

Licence

Licenca:	CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
Povezava:	http://creativecommons.org/licenses/by/4.0/deed.sl
Opis:	To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
Začetek licenciranja:	31.08.2018

Sekundarni jezik

Jezik:	Angleški jezik
Naslov:	Guidelines for the management of patients with squamous cell carcinoma of the anal canal and perianal skin (anal margin)
Povzetek:	Cancer of the anal canal and anal margin is a rare disease. In Slovenia, on average 20 patients are diagnosed with this disease each year, more women than men. However, the incidence has increased in the last year, mainly in young, homosexual men, most probably due to infections with the sexually-transmitted human papillomavirus (HPV) and human immunodeficiency virus (HIV), which are known causal agents of this disease. Cancer of the anal canal and anal margin is primarily a locoregional disease, as distant metastases are found in less than 10% of the patients. Radical radiochemotherapy plays the central role in the treatment of anal canal and anal margin carcinomas with no distant metastases, except in well-differentiated anal margin carcinomas smaller than 2 cm, where local excision is advised. Radical radiochemotherapy provides a complete response in as many as 80-90%, which is reflected also in an excellent treatment outcome with 5-year survival of 80%. Patients clinically staged as cT1-2 stand a 6.5% chance of developing inguinal lymph node metastases, while the likelihood in patients staged as cT3-4 is 16%. Surgery, namely abdominoperineal excision, has a role in the treatment of residual disease after radical radiochemotherapy. In the future, HPV vaccines hold great promise for the prevention of this virus-induced disease.

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