| Naslov: | Flash glucose monitoring addition to self-monitoring of blood glucose and perinatal outcomes in gestational diabetes : a randomized controlled trial |
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| Avtorji: | ID Zorko, Klara (Avtor)
ID Munda, Ana (Avtor)
ID Janež, Andrej (Avtor)
ID Pongrac Barlovič, Draženka (Avtor) |
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| Datoteke: |  PDF - Predstavitvena datoteka, prenos (1,19 MB)
MD5: 539EC7BAE9CDF9F1B452E87B67E8F708
 URL - Izvorni URL, za dostop obiščite https://www.ajog.org/article/S0002-9378(26)00180-8/fulltext
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| Jezik: | Angleški jezik |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: |  UKC LJ - Univerzitetni klinični center Ljubljana
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| Povzetek: | Background: Self-monitoring of blood glucose represents the standard for glycemic monitoring in gestational diabetes mellitus, while the role of continuous glucose monitoring remains uncertain. Objective: To assess whether adjunctive flash glucose monitoring improves achievement of established self-monitored glucose targets compared with self-monitoring alone and to examine maternal and neonatal outcomes. Study Design: We conducted an open-label, single-center, randomized controlled trial comparing adjunctive flash glucose monitoring plus self-monitoring of blood glucose with self-monitoring of blood glucose alone. The prespecified primary outcome was the percentage of self-monitored glucose measurements within the established target range. Secondary outcomes included maternal and neonatal outcomes. Analyses followed the intention-to-treat principle. Results: A total of 205 women (median age, 32 years; median prepregnancy body mass index, 23.5 kg/m2; median gestational age, 27 weeks) were randomized (102 to adjunctive flash glucose monitoring and 103 to self-monitoring alone). The percentage of self-monitored glucose measurements within target range was lower in the adjunctive flash monitoring group (89.5% vs 92.6%, P=.04). Median fasting and 1-hour postprandial self-monitored glucose concentrations were comparable between groups and within recommended targets. The incidence of large-for-gestational-age infants was lower in the flash monitoring group (3% vs 11%; P=.05; odds ratio, 0.27; 95% confidence interval, 0.07–0.99). Conclusion: Adjunctive flash glucose monitoring did not improve glycemic outcome in this low-risk gestational diabetes population. However, it was associated with fewer large-for-gestational-age neonates, a secondary outcome that should be interpreted cautiously given the sample size and number of events. |
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| Ključne besede: | continuous glucose monitoring, CGM, gestational diabetes, GDM, large-for-gestational-age, LGA, flash glucose monitoring, perinatal outcomes, self-monitoring of blood glucose, small-for-gestational-age |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Leto izida: | 2026 |
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| Št. strani: | str. 375-384 |
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| Številčenje: | Vol. 235, iss. 2 |
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| PID: | 20.500.12556/DiRROS-31976  |
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| UDK: | 616.379 |
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| ISSN pri članku: | 1097-6868 |
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| DOI: | 10.1016/j.ajog.2026.03.030 |
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| COBISS.SI-ID: | 274118659 |
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| Opomba: | Nasl. z nasl. zaslona;
Opis vira z dne 3. 4. 2026;
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| Datum objave v DiRROS: | 21.08.2026 |
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| Število ogledov: | 59 |
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| Število prenosov: | 30 |
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| Metapodatki: |    |
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