| Naslov: | A case report of lymphomatoid papulosis : uncovering a rare diagnosis from a common finger ulcer |
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| Avtorji: | ID Kurmuş, Gökçe Işıl (Avtor)
ID Karataş, Hanife (Avtor)
ID Güler, Elif Kaya (Avtor)
ID Cinar, Ali (Avtor)
ID Pelin Kartal, Selda (Avtor) |
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| Datoteke: |  URL - Izvorni URL, za dostop obiščite https://acta-apa.mf.uni-lj.si/journals/acta-dermatovenerol-apa/papers/10.15570/actaapa.2025.2/actaapa.2025.2.pdf
 PDF - Predstavitvena datoteka, prenos (25,45 MB)
MD5: 922D468D2D08C1F210CF9CB227640F35
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| Jezik: | Angleški jezik |
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| Tipologija: | 1.03 - Drugi znanstveni članki |
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| Organizacija: |  ZSD - Združenje slovenskih dermatovenerologov
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| Povzetek: | Lymphomatoid papulosis (LyP) is a rare, chronic CD30+ cutaneous lymphoproliferative disorder characterized by recurrent, selfhealing papulonodular lesions. Despite its benign clinical course, LyP histologically resembles malignant lymphomas, necessitating careful differentiation. A 42-year-old woman presented with a 3-year history of recurring ulcerated papulonodular lesions on her index finger. Histopathological examination revealed atypical CD30+ lymphoid proliferation, confirming LyP type A. Immunohistochemical analysis was positive for CD2, CD4, CD30, and multiple myeloma oncogene 1, while systemic malignancy was excluded. The patient was treated with low-dose methotrexate (15 mg/week), leading to symptom improvement. LyP is classified into five histological subtypes (A–E) and is often misdiagnosed due to its overlap with inflammatory and neoplastic conditions. While the condition typically resolves spontaneously, it is associated with an increased risk of secondary lymphomas, including mycosis fungoides and primary cutaneous anaplastic large cell lymphoma. Accurate diagnosis relies on clinical presentation, histopathological evaluation, and immunophenotyping. Awareness of LyP’s clinical and pathological features is essential for appropriate management and surveillance. |
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| Ključne besede: | lymphomatoid papulosis, CD30+, lymphoproliferative disorders, cutaneous T-cell lymphoma, dermatopathology |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Poslano v recenzijo: | 17.11.2024 |
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| Datum sprejetja članka: | 27.12.2024 |
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| Datum objave: | 01.09.2025 |
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| Kraj izida: | Ljubljana |
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| Založnik: | Združenje slovenskih dermatovenerologov |
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| Leto izida: | 2025 |
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| Št. strani: | str. 151-154 |
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| Številčenje: | Vol. 34, issue 3 |
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| PID: | 20.500.12556/DiRROS-29907  |
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| UDK: | 616.5:579 |
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| ISSN pri članku: | 1318-4458 |
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| DOI: | 10.15570/actaapa.2025.2 |
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| COBISS.SI-ID: | 260312323 |
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| Avtorske pravice: | Na spletni strani revije navedeno: Acta Dermatovenerologica Alpina, Pannonica et Adriatica (ISSN 1318-4458) is an open access medical journal published quarterly by the Association of Slovenian Dermatovenerologists (https://acta-apa.mf.uni-lj.si/index.php); Authors publishing in our journal retain copyright of their work under the Creative Commons Attribution License (CC BY 4.0). This license allows unrestricted use, distribution, and reproduction of the work in any medium, provided the original author(s) and copyright holder(s) are appropriately credited, and the original publication in the journal is properly cited, following established academic practices (https://acta-apa.mf.uni-lj.si/submissions.php). |
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| Datum objave v DiRROS: | 15.06.2026 |
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| Število ogledov: | 275 |
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| Število prenosov: | 179 |
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| Metapodatki: |    |
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