| Naslov: | Pbserum Specific Acne Scars® : a cutting-edge approach utilizing triple enzymatic synergy combined with microneedling for post-acne scar repair |
|---|
| Avtorji: | ID Batistella, Melania (Avtor)
ID Santaella, Erick (Avtor)
ID Oliveira, Sandra (Avtor)
ID Maan, Claudia (Avtor)
ID Kopytina, Valeria (Avtor)
ID López Berroa, Jorge (Avtor) |
|---|
| Datoteke: |  URL - Izvorni URL, za dostop obiščite https://acta-apa.mf.uni-lj.si/journals/acta-dermatovenerol-apa/papers/10.15570/actaapa.2025.16/actaapa.2025.16.pdf
 PDF - Predstavitvena datoteka, prenos (47,20 MB)
MD5: C0F07CA8C3ED347FDADC7BF4504CD6E8
|
|---|
| Jezik: | Angleški jezik |
|---|
| Tipologija: | 1.01 - Izvirni znanstveni članek |
|---|
| Organizacija: |  ZSD - Združenje slovenskih dermatovenerologov
|
|---|
| Povzetek: | Introduction: The integration of active ingredients into scientifically backed formulations is an innovative approach to remodeling post-acne atrophic scars, stimulating regenerative processes. Microneedling, a minimally invasive procedure, promotes collagen production and enhances skin penetration of cosmeceutical products such as Pbserum Specific Acne Scars®, which combines collagenases G and H with hyaluronate r-lyase and other ingredients, including allantoin, zinc sulfate, vitamin A, vitamin B3, niacinamide, and melatonin. These components modulate inflammation, fibrosis, oxidative stress, and aging. This study assesses the efficacy and safety of treatment for ameliorating atrophic acne scars. Methods: Twenty-nine patients were treated with Pbserum Specific Acne Scars® applied by microneedling for 4 months in four sessions on the middle or lower third of the face and/or periocular area. The scar size (according to EvaFace® analysis), deep skin hydration (measured with a Moisturemeter® D device), severity (assessed using the échelle d’évaluation clinique des cicatrices d’acne and Goodman and Baron scales), clinical efficacy (evaluated using Global Aesthetic Improvement Scale), quality of life (measured using Facial Acne Scar Quality of Life questionnaire), and subject satisfaction were analyzed. Results: Significant improvements were observed in all parameters evaluated, especially after four applications, demonstrating clinical efficacy. Patient satisfaction levels were notably high. Conclusions: The treatment significantly improved skin texture and scar appearance after four applications over a period of 4 months. |
|---|
| Ključne besede: | post-acne atrophic scars, collagenase, lyase, microneedling |
|---|
| Status publikacije: | Objavljeno |
|---|
| Verzija publikacije: | Objavljena publikacija |
|---|
| Poslano v recenzijo: | 23.03.2025 |
|---|
| Datum sprejetja članka: | 30.05.2025 |
|---|
| Datum objave: | 01.06.2025 |
|---|
| Kraj izida: | Ljubljana |
|---|
| Založnik: | Združenje slovenskih dermatovenerologov |
|---|
| Leto izida: | 2025 |
|---|
| Št. strani: | str. 65-72 |
|---|
| Številčenje: | Vol. 34, issue 2 |
|---|
| PID: | 20.500.12556/DiRROS-29903  |
|---|
| UDK: | 616.5:579 |
|---|
| ISSN pri članku: | 1318-4458 |
|---|
| DOI: | 10.15570/actaapa.2025.16 |
|---|
| COBISS.SI-ID: | 260269827 |
|---|
| Avtorske pravice: | Na spletni strani revije navedeno: Acta Dermatovenerologica Alpina, Pannonica et Adriatica (ISSN 1318-4458) is an open access medical journal published quarterly by the Association of Slovenian Dermatovenerologists (https://acta-apa.mf.uni-lj.si/index.php); Authors publishing in our journal retain copyright of their work under the Creative Commons Attribution License (CC BY 4.0). This license allows unrestricted use, distribution, and reproduction of the work in any medium, provided the original author(s) and copyright holder(s) are appropriately credited, and the original publication in the journal is properly cited, following established academic practices (https://acta-apa.mf.uni-lj.si/submissions.php). |
|---|
| Datum objave v DiRROS: | 15.06.2026 |
|---|
| Število ogledov: | 389 |
|---|
| Število prenosov: | 277 |
|---|
| Metapodatki: |    |
|---|
|
:
|
Kopiraj citat |
|---|
| | | | Objavi na: |  |
|---|
Postavite miškin kazalec na naslov za izpis povzetka. Klik na naslov izpiše
podrobnosti ali sproži prenos. |
