| Naslov: | The application of ultrasound sarcopenia index in sarcopenic population |
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| Avtorji: | ID Puš, Katarina (Avtor)
ID Sarto, Fabio (Avtor)
ID Narici, Marco Vincenzo (Avtor)
ID Šimunič, Boštjan (Avtor) |
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| Datoteke: |  PDF - Predstavitvena datoteka, prenos (1,45 MB)
MD5: C7F292B27CFB1C46519642CACCA94FFB
 URL - Izvorni URL, za dostop obiščite https://www.sciencedirect.com/science/article/pii/S0531556526000872?via%3Dihub
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| Jezik: | Angleški jezik |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: |  ZRS Koper - Znanstveno-raziskovalno središče Koper / Centro di Ricerche Scientifiche Capodistria
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| Povzetek: | Background: Aging leads to progressive motor system decline, which can result in sarcopenia, defined as the age- related loss of muscle mass and function. Architectural changes, epitomized by a decrease in fascicle length (Lf) and muscle thickness (MT), provide a useful signature of sarcopenia. Their ratio (Lf/MT), named ultrasound sarcopenia index (USI), is a new parameter proposed for evaluating changes in muscle geometric proportions associated with muscle atrophy but lacks application in a sarcopenic population. This study aimed to explore vastus lateralis USI in a sarcopenic population. Methods: In a sample of 139 older adults (54% females), recruited from Italy and Slovenia, we assessed muscle architecture using ultrasound imaging to measure Lf, MT, pennation angle (PA), and USI. We assessed handgrip strength, sit-to-stand test, and physical performance with timed up-and-go and gait speed. Appendicular lean mass was assessed with dual x-ray absorptiometry. Sarcopenia was classified using the EWGSOP2 and SDOC classifications. Results: Sarcopenia prevalence was 15.1% and 30.9% when classified by the EWGSOP2 and SDOC classifications, respectively. Differences in muscle architecture were observed between sarcopenic and non-sarcopenic groups, with MT showing the largest effect size (Cohen's d EWGSOP2: 0.86; SDOC:0.77). USI was higher in sarcopenic compared to non-sarcopenic individuals classified with EWGSOP2 (5.33 ± 1.30 vs 4.59 ± 0.94, p = .011, Cohen's d:0.69), confirming its sensitivity in detecting sarcopenia. Conclusion: We showed that increased USI values are associated with sarcopenia. This study shows USI as a sensitive, non-invasive marker for sarcopenia classification, supporting its use in clinical screening and monitoring of muscle changes in older adults. |
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| Ključne besede: | muscle architecture, aging, muscle quality, muscle function |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Datum objave: | 01.01.2026 |
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| Leto izida: | 2026 |
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| Št. strani: | 6 str. |
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| Številčenje: | Vol. 217, [article no.] ǂ113109 |
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| PID: | 20.500.12556/DiRROS-28619  |
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| UDK: | 612.7 |
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| ISSN pri članku: | 1873-6815 |
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| DOI: | 10.1016/j.exger.2026.113109 |
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| COBISS.SI-ID: | 273106435 |
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| Avtorske pravice: | The authors |
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| Opomba: | Nasl. z nasl. zaslona;
Soavtorji: Fabio Sarto, Marco Narici, Boštjan Šimunič;
Opis vira z dne 26. 3. 2026;
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| Datum objave v DiRROS: | 26.03.2026 |
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| Število ogledov: | 186 |
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| Število prenosov: | 88 |
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| Metapodatki: |    |
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