| Naslov: | The influence of periodontal disease and periodontal treatment on colorectal cancer |
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| Avtorji: | ID Potočnik, Urša (Avtor)
ID Brecelj, Erik (Avtor)
ID Schara, Rok (Avtor) |
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| Datoteke: |  PDF - Predstavitvena datoteka, prenos (489,87 KB)
MD5: 04A41C5A7178DF17C49C48DFDF845A8C
 URL - Izvorni URL, za dostop obiščite https://sciendo.com/article/10.2478/raon-2025-0025
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| Jezik: | Angleški jezik |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: |  UKC LJ - Univerzitetni klinični center Ljubljana
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| Povzetek: | Background: Periodontal disease (PD) is associated with more than 50 diseases and conditions, including colorectal cancer. The study aimed to investigate if periodontal treatment influences the blood levels of C-reactive protein (CRP) in colorectal cancer patients. In addition, the aim was to isolate periodontal pathogenic bacteria Fusobacterium nucleatum (FN) and Porphyromonas gingivalis (PG), which are most linked to colorectal cancer (CRC), from the mucosa of the cancer-affected intestine. Patients and methods: To assess the effect of periodontal treatment on colorectal cancer, we measured the CRP levels in the blood during cancer therapy on the day of the initial examination by the oncological surgeon, two days following surgery, and at the first follow-up appointment. We compared the CRP levels between two groups: the group of subjects who underwent periodontal treatment and the patients who did not receive periodontal disease treatment. An attempt was made to isolate the periodontal pathogenic bacteria FN and PG from the mucosa of the cancerous tissue in the colon by using quantitative culture. Results We found no statistically significant difference between the groups in the initial CRP measurements before starting cancer treatment. There was no statistically significant difference between the groups in the CRP measurements taken 1st and 2nd day after surgery and at the follow-up appointment. We could not isolate periodontal pathogenic bacteria FN and PG from cancer-altered intestine mucosa using the quantitative culture method. Conclusions Our study did not find any correlation between periodontal treatment and CRC. |
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| Ključne besede: | periodontal disease, colorectal cancer, periodontal treatment, fusobacterium nucleatum, porphyromonas gingivalis, C-reactive protein |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Leto izida: | 2025 |
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| Št. strani: | str. 589-596 |
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| Številčenje: | Vol. 59, no. 4 |
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| PID: | 20.500.12556/DiRROS-27533  |
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| UDK: | 616.31 |
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| ISSN pri članku: | 1318-2099 |
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| DOI: | 10.2478/raon-2025-0025 |
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| COBISS.SI-ID: | 237242883 |
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| Datum objave v DiRROS: | 11.02.2026 |
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| Število ogledov: | 353 |
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| Število prenosov: | 77 |
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| Metapodatki: |    |
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