| Naslov: | The Prevalence of bacterial vaginosis in pregnant women in Slovenia, determined via microscopy and semi-quantitative relative culture, and its association with adverse pregnancy outcomes |
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| Avtorji: | ID Starc, Maja (Avtor)
ID Lučovnik, Miha (Avtor)
ID Eržen Vrlič, Petra (Avtor)
ID Jeverica, Samo (Avtor) |
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| Datoteke: |  PDF - Predstavitvena datoteka, prenos (594,27 KB)
MD5: 2EF064C70A8D00D5D5DCD64EBD106F16
 URL - Izvorni URL, za dostop obiščite https://www.mdpi.com/2076-2607/13/3/588
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| Jezik: | Angleški jezik |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: |  UKC LJ - Univerzitetni klinični center Ljubljana
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| Povzetek: | Bacterial vaginosis (BV) is associated with various adverse pregnancy outcomes. It is usually diagnosed via microscopy. Semi-quantitative relative culture (SRC) was investigated as a complementary diagnostic method to determine the prevalence of BV and its association with preterm birth and preterm, premature rupture of membranes (PPROM) in pregnant women in Slovenia. We examined 3437 consecutive vaginal swabs from pregnant women during the five-year period and were able to link the results to 2531 pregnancy outcomes. The isolates were identified using MALDI-TOF, and the results were assessed by the relative amounts of Gardnerella vaginalis and lactobacilli according to two stringency criteria. The prevalence of BV was 6.5% via microscopy and was higher for SRC, 9.9% or 11.1%, depending on the stringency criteria. The association with adverse pregnancy outcomes was better when SRC was used, resulting in adjusted odds ratios of 1.76 (1.30 to 2.37) and 1.97 (1.38 to 2.82) for preterm birth and PPROM, respectively, with more stringent interpretation. Microscopically detected BV was not associated with either outcome. The clinical validity of SRC was demonstrated by its better correlation with adverse pregnancy outcomes in a large cohort of pregnant women. SRC with MALDI-TOF identification is a promising advancement of vaginal culture. |
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| Ključne besede: | bacterial vaginosis, culture, microscopy, pregnancy, preterm birth, preterm premature rupture of membranes, Slovenia |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Leto izida: | 2025 |
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| Št. strani: | 12 str. |
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| Številčenje: | Vol. 13, iss. 3, [article no.] 588 |
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| PID: | 20.500.12556/DiRROS-24482  |
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| UDK: | 618.2/.7 |
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| ISSN pri članku: | 2076-2607 |
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| DOI: | 10.3390/microorganisms13030588 |
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| COBISS.SI-ID: | 228368131 |
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| Opomba: | Nasl. z nasl. zaslona;
Opis vira z dne 9. 3. 2025;
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| Datum objave v DiRROS: | 01.12.2025 |
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| Število ogledov: | 109 |
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| Število prenosov: | 51 |
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| Metapodatki: |    |
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