| Naslov: | Bronchial bacterial colonization and the susceptibility of isolated bacteria in patients with lung malignancy |
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| Avtorji: | ID Petrovič, Sabrina (Korespondenčni avtor)
ID Beović, Bojana (Avtor)
ID Tomič, Viktorija, Univerzitetna klinika za pljučne bolezni in alergijo Golnik (Avtor)
ID Bitenc, Marko (Avtor)
ID Marc-Malovrh, Mateja, Univerzitetna klinika za pljučne bolezni in alergijo Golnik (Avtor)
ID Dimitrić, Vladimir, Univerzitetna klinika za pljučne bolezni in alergijo Golnik (Avtor)
ID Lužnik, Dane, Univerzitetna klinika za pljučne bolezni in alergijo Golnik (Avtor)
ID Miklavčič, Martina (Avtor)
ID Božič, Tamara (Avtor)
ID Gabrovec, Tina (Avtor)
ID Sadikov, Aleksander (Avtor)
ID Rozman, Aleš, Univerzitetna klinika za pljučne bolezni in alergijo Golnik (Avtor) |
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| Datoteke: |  PDF - Predstavitvena datoteka, prenos (396,66 KB)
MD5: E0714C4B49ADC97876BFCDB4B3C7CF42
 URL - Izvorni URL, za dostop obiščite https://sciendo.com/article/10.2478/raon-2025-0018
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| Jezik: | Angleški jezik |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: |  UKPBAG - Univerzitetna klinika za pljučne bolezni in alergijo Golnik
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| Povzetek: | Background Postoperative pneumonia (POP) remains a leading cause of mortality following lung surgery. Recent studies have confirmed that the respiratory tract below the vocal cords is not sterile and often harbours potentially pathogenic microorganisms (PPMs), putting patients with lung malignancies at an increased risk for pulmonary infections. Patients and methods The study analysed 149 patients who underwent bronchoscopy for lung lesions suspected to be lung cancer. Protected specimen brush (PSB) samples were obtained during bronchoscopy prior to any specific treatment. Bacterial identification and antimicrobial susceptibility testing were conducted on the isolated strains. Results Bacterial colonization was detected in 88.6% of patients, with 21.5% carrying PPMs. Notably, patients with type 2 diabetes exhibited a higher rate of PPM colonization compared to others. Antibiotic susceptibility testing showed no significant differences in efficacy between amoxicillin with clavulanic acid and first-generation cephalosporin in both colonized patients and those with PPMs. Importantly, no multidrug-resistant bacteria were identified. Conclusions Our findings indicate a slightly lower PPM colonization rate compared to previous studies, possibly due to the unique geographic characteristics of the study population. The absence of significant differences in bacterial susceptibility between the two tested antibiotics highlights the need for further research to refine perioperative infection management strategies. |
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| Ključne besede: | bronchial bacterial colonization, potentially pathogenic microorganisms, antibiotic prophylaxis |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Poslano v recenzijo: | 15.04.2024 |
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| Datum sprejetja članka: | 19.01.2025 |
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| Datum objave: | 27.02.2025 |
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| Založnik: | Association of Radiology and Oncology |
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| Leto izida: | 2025 |
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| Št. strani: | str. 147-152 |
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| Številčenje: | Vol. 59, iss. 1 |
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| Izvor: | Radiology and oncology |
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| PID: | 20.500.12556/DiRROS-22542  |
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| UDK: | 616-022.1:615.33 |
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| ISSN pri članku: | 1581-3207 |
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| DOI: | 10.2478/raon-2025-0018 |
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| COBISS.SI-ID: | 228325123 |
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| Avtorske pravice: | © 2025 Sabrina Petrovic et al., published by Sciendo
This work is licensed under the Creative Commons Attribution 4.0 International License. |
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| Opomba: | Nasl. z nasl. zaslona;
Opis vira z dne: 7. 3. 2025;
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| Datum objave v DiRROS: | 03.06.2025 |
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| Število ogledov: | 528 |
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| Število prenosov: | 260 |
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| Metapodatki: |    |
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