| Naslov: | Key differences between chronic inducible and spontaneous urticaria |
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| Avtorji: | ID Bizjak, Mojca, Univerzitetna klinika za pljučne bolezni in alergijo Golnik (Avtor)
ID Košnik, Mitja, Univerzitetna klinika za pljučne bolezni in alergijo Golnik (Avtor) |
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| Datoteke: |  URL - Izvorni URL, za dostop obiščite https://www.frontiersin.org/journals/allergy/articles/10.3389/falgy.2024.1487831/full
 PDF - Predstavitvena datoteka, prenos (6,77 MB)
MD5: B80ACF4AA7B7B6DD71A97E9E146D4B04
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| Jezik: | Angleški jezik |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: |  UKPBAG - Univerzitetna klinika za pljučne bolezni in alergijo Golnik
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| Povzetek: | Introduction: The latest international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for urticaria recommends limited laboratory testing for chronic spontaneous urticaria (CSU) and selective testing for only certain chronic inducible urticaria (CIndU) subtypes, though the rationale for these recommendations is poorly explained. This study aimed to improve the understanding of CIndU subtypes by comprehensively comparing their demographic, clinical, and laboratory characteristics with those of the better-characterized CSU.
Methods: We conducted a retrospective analysis of 567 patients (median age 41 years, 67% female) diagnosed with CSU, symptomatic dermographism (SD), cold urticaria (ColdU), cholinergic urticaria (CholU), and delayed pressure urticaria (DPU).
Results: Our findings revealed that patients with SD, ColdU, and CholU had lower levels of C-reactive protein (CRP), higher total serum immunoglobulin E (IgE) levels, and higher basophil counts compared to CSU patients. These subtypes also had distinct demographic and clinical features, such as a younger age of onset and a longer disease duration. In contrast, patients with DPU had significantly higher CRP levels and neutrophil counts compared to those with CSU.
Discussion: These findings highlight the heterogeneity among chronic urticaria subtypes, suggesting that a tailored approach to laboratory testing may be more effective. The distinct immunological and clinical features observed in CIndU subtypes suggest a need for subtype-specific diagnostic and therapeutic guidelines. |
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| Ključne besede: | blood cell count, C-reactive protein, chronic inducible urticaria, chronic spontaneous urticaria, immunoglobulin E |
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| Poslano v recenzijo: | 28.08.2024 |
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| Datum sprejetja članka: | 04.10.2024 |
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| Datum objave: | 17.10.2024 |
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| Kraj izida: | Lausanne |
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| Založnik: | Frontiers Media |
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| Leto izida: | 2024 |
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| Št. strani: | str. 1-11 |
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| Številčenje: | Vol. 5 |
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| Izvor: | Frontiers in allergy |
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| PID: | 20.500.12556/DiRROS-21530  |
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| UDK: | 616.5 |
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| ISSN pri članku: | 2673-6101 |
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| DOI: | 10.3389/falgy.2024.1487831 |
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| COBISS.SI-ID: | 212055811 |
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| Avtorske pravice: | © 2024 Bizjak and Košnik. This is an openaccess article distributed under the terms of
the Creative Commons Attribution License (CC BY). The use, distribution or reproduction
in other forums is permitted, provided the original author(s) and the copyright owner(s)
are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted
which does not comply with these terms. |
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| Opomba: | Nasl. z nasl. zaslona;
Opis vira z dne 18. 10. 2024;
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| Datum objave v DiRROS: | 21.02.2025 |
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| Število ogledov: | 582 |
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| Število prenosov: | 390 |
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| Metapodatki: |    |
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