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Naslov:Awake craniotomy for operative treatment of brain gliomas - experience from University Medical Centre Ljubljana
Avtorji:ID Žele, Tilen (Avtor)
ID Velnar, Tomaž (Avtor)
ID Koritnik, Blaž (Avtor)
ID Bošnjak, Roman (Avtor)
ID Markovič Božič, Jasmina (Avtor)
Datoteke:URL URL - Izvorni URL, za dostop obiščite https://www.radioloncol.com/index.php/ro/article/view/3978/5157
 
.pdf PDF - Predstavitvena datoteka, prenos (2,36 MB)
MD5: B67EBD4AA1918660902E5F8E330F7E29
 
Jezik:Angleški jezik
Tipologija:1.01 - Izvirni znanstveni članek
Organizacija:Logo OI - Onkološki inštitut Ljubljana
Povzetek:Background. Awake craniotomy is a neurosurgical technique that allows neurophysiological testing with patient cooperation during the resection of brain tumour in regional anaesthesia. This allows identification of vital functional (i.e. eloquent) brain areas during surgery and avoidance of their injury. The aim of the study was to present clinical experience with awake craniotomy for the treatment of gliomas at the University Medical Centre Ljubljana from 2015 to 2019.Patients and methods. Awake craniotomy was considered in patients with a gliomas near or within the language brain areas, in all cases of insular lesions and selected patients with lesions near or within primary motor brain cortex. Each patient was assessed before and after surgery.Results. During the 5-year period, 24 awake craniotomies were performed (18 male and 6 female patients; average age 41). The patient’s cooperation, discomfort and perceived pain assessed during the awake craniotomy were in majority of the cases excellent, slight, and moderate, respectively. After surgery, mild neurological worsening was observed in 13% (3/24) of patients. Gross total resection, in cases of malignant gliomas, was feasible in 60% (6/10) and in cases of low-grade gliomas in 29% (4/14). The surgery did not have important negative impact on functional status or quality of life as assessed by Karnofsky score and Short-Form 36 health survey, respectively (p > 0.05). Conclusions. The results suggest that awake craniotomy for treatment of gliomas is feasible and safe neurosurgical technique. The proper selection of patients, preoperative preparation with planning, and cooperation of medical team members are necessary for best treatment outcome.
Ključne besede:awake craniotomy, surgery of gliomas, intraoperative neurophysiological testing, primary brain tumours, clinical experiences
Status publikacije:Objavljeno
Verzija publikacije:Objavljena publikacija
Datum objave:01.06.2023
Založnik:Association of Radiology and Oncology
Leto izida:2023
Št. strani:str. 191-200
Številčenje:Vol. 57, no. 2
Izvor:Ljubljana
PID:20.500.12556/DiRROS-19842 Novo okno
UDK:616-089.888.5
ISSN pri članku:1318-2099
DOI:10.2478/raon-2022-0052 Novo okno
COBISS.SI-ID:165072899 Novo okno
Avtorske pravice:by Authors
Opomba:Soavtorji: Tomaz Velnar, Blaz Koritnik, Roman Bosnjak, Jasmina Markovic Bozic;
Datum objave v DiRROS:25.07.2024
Število ogledov:440
Število prenosov:473
Metapodatki:XML DC-XML DC-RDF
:
ŽELE, Tilen, VELNAR, Tomaž, KORITNIK, Blaž, BOŠNJAK, Roman in MARKOVIČ BOŽIČ, Jasmina, 2023, Awake craniotomy for operative treatment of brain gliomas - experience from University Medical Centre Ljubljana. Radiology and oncology [na spletu]. 2023. Vol. 57, no. 2, p. 191–200. [Dostopano 4 april 2025]. DOI 10.2478/raon-2022-0052. Pridobljeno s: https://dirros.openscience.si/IzpisGradiva.php?lang=slv&id=19842
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Gradivo je del revije

Naslov:Radiology and oncology
Skrajšan naslov:Radiol. oncol.
Založnik:Slovenian Medical Society - Section of Radiology, Croatian Medical Association - Croatian Society of Radiology
ISSN:1318-2099
COBISS.SI-ID:32649472 Novo okno

Sekundarni jezik

Jezik:Slovenski jezik
Ključne besede:kraniotomija v budnem stanju klinične izkušnje, kirurgija gliomov, intraoperativno nevrofiziološko testiranje, primarni možganski tumorji


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