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Povzetek: Despite numerous attempts to integrate dream research into a vast array of sci-entific disciplines, there appears to be no consensus on why and how we dream. This millennia-old universal human phenomenon appears to be too elusive to be thoroughly understood by a single scientific discipline and too complex and data--rich to be studied only theoretically. However, another dimension to dreams and dreaming could promise an integrative approach: the culture-historical compo-nent that merges with recent advances in artificial Intelligence. This paper briefly examines conceptual understandings of dreams before the dawn of modern science – specifically, the Native american, Mesopotamian, ancient Greek, and Hippocra-tic principles of dream practices and knowledge – in an attempt to understand the contemporary dream research field better and to outline future avenues for a data-driven approach while remaining grounded in its epistemological foundation.
Ključne besede: ancient dreaming, archetypes, artificial intelligence, dream data, cross-cultural dream analysis
Objavljeno v DiRROS: 13.05.2024; Ogledov: 27; Prenosov: 14
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Povzetek: This paper presents results from an experimental assessment of glued-in rods in cross laminated timber (CLT). For the purposes of the study more than 60 pull-pull tests were performed, where the specimens varied in terms of bonded-in length (from 80 to 400 mm), rod diameter (16-24 mm) and rod-to-grain angle (parallel and perpendicular). Several different failure modes that are not common for other applications of glued-in rods (e.g., a failure between CLT layers) were obtained for the analysed CLT specimens. It was found that these failure mechanisms can substantially influence the obtained ultimate tension loads. At the end, the experimental results were compared with empirical and semi-empirical equations for estimating the pull-out strength of glued-in rods in structural timber and glulam. The comparison showed that most of the existing equations overestimate the ultimate tension loads for specimens with the rod parallel to the grain and underestimate the ultimate tension load for specimens with the rod perpendicular to the grain. The results vary because the possible CLT failure modes were not included in previous studies. Further studies are proposed to improve the equations for glued-in rods in CLT.
Ključne besede: glued-in rods, cross laminated timber (CLT), pull-pull experiment, glued-in length, rod-to-grain angle, failure mechanisms in CLT
Objavljeno v DiRROS: 29.11.2023; Ogledov: 223; Prenosov: 179
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Povzetek: Numerical simulations and parametric studies of glued-in rods in cross-laminated timber have been performed. The simulations were based on 3D finite element analysis, using a cohesive surface model for the bond-lines between the laminations and the bond-line along the rod. The parametric studies investigated the influence of the glued-in length, the rod diameter, and the rod-to-grain angle on the load-bearing capacity and stiffness of the connection. The analyses showed that the load-bearing capacity generally increases with the glued-in length and the rod diameter, which agrees well with experiments. For different rod-to-grain angles, different mechanical behaviour was observed, especially considering the failure modes.
Ključne besede: glued-in rods, cross laminated timber (CLT), parametric study, nonlinear numerical modelling, glued-in length, rod diameter, rod orientation
Objavljeno v DiRROS: 13.09.2023; Ogledov: 252; Prenosov: 153
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Povzetek: Importance: The effects of chlorhexidine (CHX) mouthwash, selective oropharyngeal decontamination (SOD), and selective digestive tract decontamination (SDD) on patient outcomes in ICUs with moderate to high levels of antibiotic resistance are unknown. Objective: To determine associations between CHX 2%, SOD, and SDD and the occurrence of ICU-acquired bloodstream infections with multidrug-resistant gram-negative bacteria (MDRGNB) and 28-day mortality in ICUs with moderate to high levels of antibiotic resistance. Design, setting, and participants: Randomized trial conducted from December 1, 2013, to May 31, 2017, in 13 European ICUs where at least 5% of bloodstream infections are caused by extended-spectrum [beta]-lactamase-producing Enterobacteriaceae. Patients with anticipated mechanical ventilation of more than 24 hours were eligible. The final date of follow-up was September 20, 2017. Interventions: Standard care was daily CHX 2% body washings and a hand hygiene improvement program. Following a baseline period from 6 to 14 months, each ICU was assigned in random order to 3 separate 6-month intervention periods with either CHX 2% mouthwash, SOD (mouthpaste with colistin, tobramycin, and nystatin), or SDD (the same mouthpaste and gastrointestinal suspension with the same antibiotics), all applied 4 times daily. Main outcomes and measures: The occurrence of ICU-acquired bloodstream infection with MDRGNB (primary outcome) and 28-day mortality (secondary outcome) during each intervention period compared with the baseline period. Results: A total of 8665 patients (median age, 64.1 years; 5561 men [64.2%]) were included in the study (2251, 2108, 2224, and 2082 in the baseline, CHX, SOD, and SDD periods, respectively). ICU-acquired bloodstream infection with MDRGNB occurred among 144 patients (154 episodes) in 2.1%, 1.8%, 1.5%, and 1.2% of included patients during the baseline, CHX, SOD, and SDD periods, respectively. Absolute risk reductions were 0.3% (95% CI, -0.6% to 1.1%), 0.6% (95% CI, -0.2% to 1.4%), and 0.8% (95% CI, 0.1% to 1.6%) for CHX, SOD, and SDD, respectively, compared with baseline. Adjusted hazard ratios were 1.13 (95% CI, 0.68-1.88), 0.89 (95% CI, 0.55-1.45), and 0.70 (95% CI, 0.43-1.14) during the CHX, SOD, and SDD periods, respectively, vs baseline. Crude mortality risks on day 28 were 31.9%, 32.9%, 32.4%, and 34.1% during the baseline, CHX, SOD, and SDD periods, respectively. Adjusted odds ratios for 28-day mortality were 1.07 (95% CI, 0.86-1.32), 1.05 (95% CI, 0.85-1.29), and 1.03 (95% CI, 0.80-1.32) for CHX, SOD, and SDD, respectively, vs baseline. Conclusions and relevance: Among patients receiving mechanical ventilation in ICUs with moderate to high antibiotic resistance prevalence, use of CHX mouthwash, SOD, or SDD was not associated with reductions in ICU-acquired bloodstream infections caused by MDRGNB compared with standard care.
Ključne besede: anti-infective agents -- therapeutic use, bacteremia -- prevention and control, chlorhexidine -- therapeutic use, cross infection -- prevention and control, disinfection -- methods, bacterial drug resistance, gastrointestinal tract -- microbiology, Gram-negative bacterial infections -- prevention and control, hospital mortality, intensive care units, mouthwashes -- therapeutic use, oropharynx -- microbiology, artificial respiration, multicenter study, randomized controlled trial
Objavljeno v DiRROS: 09.11.2020; Ogledov: 1241; Prenosov: 402
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