1. Surgical treatment of malignant pleural mesotheliomaJanez Eržen, Stanko Vidmar, Mihael Sok, Andrej Debeljak, Peter Kecelj, Viljem Kovač, Marjeta Stanovnik, Tomaž Rott, Izidor Kern, 2005, izvirni znanstveni članek Povzetek: Background. The aim of the study was to identify perioperative morbidity and mortality, the category and mode of adjuvant treatment, local recurrence and survival in patients treated by extrapleural pneumonectony (EPP) for malignantpleural mesothelioma (NLPM). Methods. From 2000 to 2003, 18 patients with MPM were referred to the Department of Thoracic Surgery in Ljubljana, and17 of them were operated on. Two patients underwent explorative thoracotomy, and 15 patients were evaluated. Five female and nine male patients (aged 52-68 years) were treated by EPP and one male patient by pleurectomy. Eight patients received both adjuvant chemotherapy (ChT) and radiotherapy (RT), with cisplatin 100 mg/m2 + mitomycin C 6-10 mg/m2 gemcitabine 1000 mg/m2 and external beam radiation with 24 Gy - 58 Gy respectively, three patients received no adjuvant therapy, three patients weretreated by adjuvant ChT, two of them were given cisplatin 100 mg/m2 + mitomycin C 6-10 mg/m2, and one patient cisplatin 100 mg/m2 on the first day and gemcitabine 250 mg/rn2 in prolonged 6 hours infusion on the first and on the eighth day. One patient was treated only by adjuvant RT. Results. There were no perioperative deaths and the postoperative morbidity was 42%. Of the 15 evaluable patients, and in the median follow up of 40 months (28-64), we noticed nine (60.0%) recurrences, seven local and two abdominal. Eight (53.3%)patients died, all because of the local progress of disease. (Abstract truncated at 2000 characters) Objavljeno v DiRROS: 14.02.2024; Ogledov: 671; Prenosov: 146
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2. Importance of surgery in the multimodality treatment for small cell lung cancer (SCLC)A... Schamanek, K... Karrer, Janez Orel, Janez Eržen, Bogomir Hrabar, Metka Klevišar, Miha Debevec, Tomaž Rott, 1994, izvirni znanstveni članek Objavljeno v DiRROS: 11.01.2024; Ogledov: 672; Prenosov: 188
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3. p53 and lung cancer - more frequent p53 overexpression in patients with multiple primary tumoursTomaž Rott, Mario Poljak, Olga Staniša, Janez Orel, Andrej Debeljak, 1994, strokovni članek Ključne besede: rak (medicina), pljuča, pljučni rak, biokemija, geni Objavljeno v DiRROS: 11.01.2024; Ogledov: 705; Prenosov: 197
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4. Biological behaviour of lung carcinoids : a retrospective analysis of 71 patientsIzidor Kern, Tomaž Rott, Marija Zupančič, Jurij Šorli, Urška Gantar-Rott, Janez Eržen, Janez Orel, Bogo Hrabar, 1994, strokovni članek Ključne besede: rak (medicina), pljuča, pljučni rak, novotvorbe Objavljeno v DiRROS: 11.01.2024; Ogledov: 646; Prenosov: 206
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6. Detection of early lung cancer lesions in surgical resections and in bronchial and transbronchial biopsiesTomaž Rott, Maja Jerše, Marjeta Terčelj-Zorman, Janez Eržen, 2006, objavljeni znanstveni prispevek na konferenci (vabljeno predavanje) Povzetek: Background. Overall bad progmpsis of lung is mostly due to too late detection of early lung cancer, which may be teated with good success. Therefore different diagnostic methods are developing for more efficient detection of early lung cancer: besides modern radiological, bronchoscopic methods with additional fluorescence techniques, quantitative cytological investigations, also histological and molecular investigations are included. History may reveal early preinvasive lung xcancer lesions, associated early during multistep lung carcinogemesis with molecular genetic changes. Patients and methods. Preinvasive epithelial lung cancer lesions we searched in two groups of patients. In the first group of 316 patients from the period March 2003 - August 2006, 498 bronchial and transbronchial biopsies were examined for squamous metaplasia and dysplasia, carcinoma in situ, and invasive tumours. Inthe second group of 238 patients from the period January 2004 - August 2006,resected primary lung tumours were analysed for preinvasive neuroendocrine tumours and atypical adenomatous hyperplasia. Resuots. The mostfrequent changes in bronchial and transbronchial biopsies were squamous metaplasia (46.5%), simple or goblet cell hyperplasia of the bronchial epithelium (44.3%), malignant tumours (20.66%) and squamous dysplasia (16.1%),but rare carcinoma in situ (0.63%). Diffuse idiopoathic pulmonary neuroendocrine cell hyperplasia was found in 15 (6.3%) cases in the vicinity of 238 resected lung cancer specimens, carcinoid in12 patients (5%), and mostly combined large neuroendocrine cancer in 21 patients (8.8%). Atypical denomatous hyperplasia was found in 2 patients. Conculsions. Classical histological analysis should be focused on detection of early preinvasive epithelial lung cancer lesions. (Abstract truncated at 2000 characters). Objavljeno v DiRROS: 05.12.2023; Ogledov: 622; Prenosov: 161
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7. Smernice za diagnostiko in zdravljenje bolnikov z rakom pljučJože Antonič, Tanja Bavčar-Vodovnik, Olga Cerar, Rok Cesar, Anton Crnjac, Andrej Debeljak, Majda Drnovšek, Janez Eržen, Matjaž Fležar, Jože Jerman, Maja Jerše, Peter Kecelj, Izidor Kern, Igor Kocijančič, Viljem Kovač, Nada Rotovnik-Kozjek, Karmen Kramer Vrščaj, Slavica Lahajnar, Ilonka Osrajnik, Tomaž Rott, Andreja A. Schwarzbartl-Pevec, Anja Simonič, Uroš Smrdel, Mihael Sok, Andreja Cirila Škufca Smrdel, Saša Štern, Marjeta Terčelj-Zorman, Nadja Triller, Matjaž Turel, Tomaž Varga, Bojan Veingerl, Barbara Vidergar-Kralj, Stanko Vidmar, Martina Vrankar, Vesna Zadnik, Branko Zakotnik, Jurij Zalar, Anton Zorko, slovar, enciklopedija, leksikon, priročnik, atlas, zemljevid Objavljeno v DiRROS: 27.05.2020; Ogledov: 2780; Prenosov: 793
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