Iskanje po repozitoriju

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Povzetek: Rak dojk je v Sloveniji najpogostejši rak pri ženskah. Leta 1995 je za njim zbolelo 784 žensk (76,7/100.000), pričakujemo pa , da se bo v prihodnjih desetih letih incidenca še večala. Delež rakov, odkritih v omejenem stadiju se povečuje; leta 1995 je bilo takih 44% vseh primerov. Čeprav se je preživetjolnic izboljšalo (67-odstotno 5-letno relativno preživetje bolnic z rakritim v letih 1988-92), ostaja rak dojk pri ženskah na prvem mestu med vzroki smrti zaradi raka. Med dikazane nevarnostne dejavnike sodijo poleg spola in starosti še poprejšnji rak dojk , nekatere benigne bolezni dojk, družinska obremenitev, ionizirajoče sevanje, nekateri reproduktivni dejavniki in debelost. V primarni preventivi zaenkrat ni posebnih priporočil, so le splošna: vzdrževanje normalne telesne teže, pravilna prehrana, telesna dejavnost in zmernost pri pitju alkoholnih pijač. Ocenjujejo, da presejanje, redno mamografsko pregledovannje žensk po 50. letu starosti z dodatnim kliničnim pregledom ali brez njega, zmanjša umrljivost za rakom dojk med pregledanimi za okrog 30%. Populacijsko presejanje priporočajo večinoma po 50.letu starosti. Problem raka dojk je mogoče reševati celostno, s primarno preventivo, zgodnjim odkrivanjem in dostopnostjo do užinkovitega zdravljenja, predvsem pa z vlaganjem sredstev tja, kjer je razmerje med stroški in koristjonajugodnejše.
Objavljeno v DiRROS: 21.11.2023; Ogledov: 228; Prenosov: 89
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Povzetek: The present study deals with the characterisation of pigments used in two overlaid gothic wall paintings from the former 13th century Minorite church of St. Francis of Assisi (Koper, Slovenia), in order to define differences in the technologies used. Paint layer samples were analysed via Raman microspectroscopy, supported by SEM/EDS and FTIR analysis, when necessary. The results revealed that the 14th century mural was painted mainly a fresco with final elements a secco, a technique typical of Italian mediaeval wall painting. In contrast, the 15th century painting was executed mostly a secco, a technique often applied in Northern Europe and the Alpine region. The differences between the two paintings are especially obvious in the pigments applied. While the earlier painting is characterised by azurite, carbon black, red and yellow ochres, lime white and green earth, the palette used for the younger painting is much broader. In addition to red and yellow ochres, carbon black and lime white, lead pigments such as lead white, red lead and lead-tin yellow type I were also determined, as well as a number of expensive pigments including cinnabar, azurite and malachite. Also found in the younger painting was the rare orange yellow pigment vanadinite. In both layers, azurite was applied a secco for the background area. Gilding was confirmed in both layers, carried out as application of gold leaves on red bole (in the earlier mural) and on mordant (on a younger, superimposed (overlaid painting), which is quite exclusive and rare for Slovene mediaeval painting. In the younger layer also a use of tin foil for secondary elements was discovered.
Ključne besede: wall paintings, pigments, Gothic, golding, Raman microspectroscopy
Objavljeno v DiRROS: 27.10.2023; Ogledov: 393; Prenosov: 158
Celotno besedilo (4,58 MB)
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Ključne besede: terminalni bolniki, umirajoči, zdravstvena oskrba, povzetki, zborniki, elektronske knjige
Objavljeno v DiRROS: 23.10.2023; Ogledov: 316; Prenosov: 129
Celotno besedilo (11,71 MB)
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Povzetek: Background: Neuromuscular dysfunction is common in older adults and more pronounced in neurodegenerative diseases. In Parkinson's disease (PD), a complex set of factors often prevents the effective performance of activities of daily living that require intact and simultaneous performance of the motor and cognitive tasks. Methods: The cross-sectional study includes a multifactorial mixed-measure design. Between-subject factor grouping the sample will be Parkinson’s Disease (early PD vs. healthy). The within-subject factors will be the task complexity (single- vs. dual-task) in each motor activity, i.e., overground walking, semi-tandem stance, and isometric knee extension, and a walking condition (wide vs. narrow lane) will be implemented for the overground walking activity only. To study dual-task (DT) effects, in each motor activity participants will be given a secondary cognitive task, i.e., a visual discrimination task for the overground walking, an attention task for the semi-tandem, and mental arithmetic for the isometric extension. Analyses of DT effects and underlying neuronal correlates will focus on both gait and cognitive performance where applicable. Based on an a priori sample size calculation, a total N = 42 older adults (55-75 years) will be recruited. Disease-specific changes such as laterality in motor unit behavior and cortical control of movement will be studied with high-density surface electromyography and electroencephalography during static and dynamic motor activities, together with whole-body kinematics. Discussion: This study will be one of the first to holistically address early PD neurophysiological and neuromuscular patterns in an ecologically valid environment under cognitive-motor DT conditions of different complexities. The outcomes of the study aim to identify the biomarker for early PD either at the electrophysiological, muscular or kinematic level or in the communication between these systems.
Ključne besede: Parkinson's disease, mobile brain imaging, body brain imaging, MoBi, dual tasking, neuromuscular function, older adults
Objavljeno v DiRROS: 15.09.2023; Ogledov: 346; Prenosov: 152
Celotno besedilo (1,36 MB)
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Ključne besede: nanofibers, aerosols, filtration
Objavljeno v DiRROS: 15.09.2023; Ogledov: 267; Prenosov: 148
Celotno besedilo (2,07 MB)
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