111. Ocena kadrovskih potreb za izvajanje zdravljenja raka v Republiki SlovenijiKatarina Lokar, Marjana Bernot, Maja Ebert Moltara, Mateja Marc-Malovrh, Radivoje Pribaković Brinovec, Brigita Skela-Savič, Vesna Zadnik, Tina Žagar, Branko Zakotnik, 2020, strokovni članek Ključne besede: načrtovanje zdravstvenega osebja, zdravljenje raka, paliativna oskrba, incidenca, umrljivost, napovedovanje
Objavljeno v DiRROS: 18.03.2021; Ogledov: 1489; Prenosov: 435
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112. Deset let Državnega presejalnega programa za raka dojk DoraKatja Jarm, Kristijana Hertl, Mateja Krajc, Cveto Šval, Veronika Kutnar, Mateja Kurir-Borovčić, Maja Primic-Žakelj, Vesna Zadnik, Maksimiljan Kadivec, 2020, izvirni znanstveni članek Povzetek: Priporočila za vzpostavitev presejalnih programov za raka dojk je leta 2003 izdala Evropska komisija in države članice Evropske unije pozvala, da jih vzpostavijo do leta 2008. V Sloveniji od leta 2008 deluje Državni program za raka dojk DORA, ki je konec leta 2017 vključeval vse slovenske ženske iz
ciljne skupine. Ženske v starosti od 50 do 69 let so vsaki dve leti pisno vabljene na presejalni pregled z mamografijo, ki omogoča odkritje še netipnih sprememb v dojki. Ob sumljivih spremembah na mamografiji so povabljene na nadaljnjo obravnavo, če je odkrit rak dojke, pa tudi na zdravljenje. Od leta 2018 v okviru programa deluje 21 mamografov v 16 stacionarnih in 3 mobilnih presejalnih
enotah, kjer se opravljajo presejalne mamografije, in 2 presejalno- diagnostična centra za nadaljnjo obravnavo žensk in zdravljenje raka, odkritega v presejanju. Program DORA deluje v skladu z visokimi standardi Evropskih smernic za zagotavljanje kakovosti presejanja za raka dojk in zagotavlja enako obravnavo za vse udeleženke v katerikoli presejalni enoti v Sloveniji. Cilj presejalnega programa je ob vsaj 70-odstotni udeležbi žensk doseči znižanje umrljivosti za rakom dojk v ciljni populaciji za 25–30 %. Letno merjeni kazalniki kakovosti programa kažejo, da je program učinkovit in vodi k omenjenemu cilju. Značilnosti slovenskega organiziranega programa so: centraliziran populacijski program, vabljenje žensk z vnaprej določenim terminom slikanja, dvojno odčitavanje, konsenz konferenca, nadaljnja obravnava je del presejalnega postopka, multidisciplinarni sestanki, presejalni register z enotno aplikacijo za vnašanje vseh presejalnih korakov, od vabila do mamografij in nadaljnje obravnave, nadzor kakovosti dela radioloških inženirjev in radiologov, stalen strokovni nadzor nad izvajalci programa in letno merjenje kazalnikov kakovosti programa.
Ključne besede: presejalni programi, rak dojk, presejalni register
Objavljeno v DiRROS: 18.03.2021; Ogledov: 1419; Prenosov: 413
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113. Ovrednotenje in karakterizacija biomaseDarja Stare, Špela Ščap, Rok Mihelič, Sara Mavsar, Mateja Mešl, Miha Humar, Ilja Gasan Osojnik Črnivec, Nina Barbara Križnik, Blaž Likozar, Primož Oven, Luka Juvančič, 2020, elaborat, predštudija, študija Ključne besede: biogospodarstvo, biomasa, razpoložljivost biomase, izkoriščenost potencialov
Objavljeno v DiRROS: 16.03.2021; Ogledov: 1158; Prenosov: 501
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114. Obvladovanje raka v času COVIDA-19 v luči preventive : XXVIII. seminar "In memoriam dr. Dušana Reje" : Ljubljana, 3. december 20202020, zbornik strokovnih ali nerecenziranih znanstvenih prispevkov na konferenci Ključne besede: pandemije, preventivni programi, preventivni ukrepi, življenjski slog, telesna neaktivnost, kajenje, pivske navade, humani papiloma virus, vakcinacija, zgodnja diagnostika, presejalni programi, raziskovalno delo, zborniki
Objavljeno v DiRROS: 27.01.2021; Ogledov: 1511; Prenosov: 429
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115. Towards a holistic approach to the geochemistry of solid inorganicparticles in the urban environmentMartin Gaberšek, Mateja Gosar, 2021, izvirni znanstveni članek Povzetek: Airborne particulate matter (PM) has a major impact on the biogeochemical cycles of chemical elements in theurban environment. Anthropogenic-derived PM emissions are the cause of some of the most severe environmen-tal and health problems. The presented study aims to improve our knowledge of PM dynamics by introducing amulti-media, multi-analytical and multi-elemental holistic approach to geochemical studies of inorganic PM inthe urban environment. The importance of the holistic approach is highlighted and its application in a casestudy of Maribor (Slovenia) is presented. The chemical composition and individual particulate characteristicsof street, attic and household dust were determined and compared with the characteristics of airborne PM,and PM deposited in snow, together with the chemical composition of the soil. We found that the mineralogicaland chemical composition and the individual solid particle characteristics of the studied media differ consider-ably. Nevertheless, minerals of geogenic origin are present in all media. The highest levels of potentially toxic el-ements (PTEs) in all media, except household dust, are typical for industrial areas. Street dust primarily reflectsthe influence of winter road maintenance and industrial activities, while characteristics of household dust arepredominantly influenced by indoor activities and properties of dwellings. The comparison of the chemical com-position of attic and street dust indicates that emissions of As, Cd, Pb, S and Zn were higher in the past. The char-acterisation of airborne PM and PM deposited in snow is essential for the identification of the mostrecentsourcesof PTE-bearing particles. Several industrial sources and the fate of some particle types in the environment havebeen determined based on thefindings of the SEM/EDS analyses. This study confirms that various environmentalmedia are carriers of diverse geochemical information and highlights the importance of a holistic approach ingeochemistry of PM in urban areas.
Ključne besede: Street dust, attic dust, household dust, airborne particulate matter, potentially toxic elements, SEM/EDS
Objavljeno v DiRROS: 06.01.2021; Ogledov: 1730; Prenosov: 843
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116. GLCCI1 polymorphism rs37973 and asthma treatment response to inhaled corticosteroidsMatija Rijavec, Mateja Žavbi, Anton Lopert, Matjaž Fležar, Peter Korošec, 2018, izvirni znanstveni članek Povzetek: Background. Asthma treatment response is highly variable and pharmacogenetic markers that predict treatment response would be one step closer to personalized treatment. GWAS studies have shown that polymorphisms GLCCI1 could be associated with asthma treatment response to inhaled corticosteroids (ICS). Materials and methods. We genotyped rs37973 of GLCCI1 in 208 adult asthma patients treated with ICS. Change in % predicted FEV1 was analysed after short-term (3 months) and after long-term (at least 3 years) treatment. Treatment success was defined as good when FEV1 decreased less than 30 ml/year. Results. After 3 months of treatment, change of % predicted FEV1 was higher in patients with GG genotype than in patients with AG+AA genotype, and this genotype dependent difference was only evident in non-smokers. Similar results were found after at least 3 years of treatment when all patients were analysed, in non-smokers and patients with atopy. Even though, no differences in treatment success (good vs. poor response) were observed when analysing the entire group of patients, genotype dependent treatment success was highly influenced by smoking and atopy. GG genotype was overrepresented in non-smokers and patients with atopy with good response. Conclusions. Rs37973 was associated with short- and long-term treatment response; however, there was a great influence of smoking and atopy on pharmacogenetic association. Furthermore, we found GG genotype to be associated with better treatment response, what is contrary to results found in GWAS.
Ključne besede: asthma -- diagnosis -- therapy, pharmacogenetics, genetic polymorphism, smoking, inhaled corticosteroids, atopy, GLCCI1, FEV1, rs37973
Objavljeno v DiRROS: 16.12.2020; Ogledov: 1431; Prenosov: 393
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119. Priporočila za obravnavo bolnikov s pljučnim rakomMartina Vrankar, Nina Boc, Izidor Kern, Aleš Rozman, Karmen Stanič, Tomaž Štupnik, Mojca Unk, Maja Ebert Moltara, Vesna Zadnik, Katja Adamič, Jernej Benedik, Marko Bitenc, Jasna But-Hadžić, Anton Crnjac, Eva Ćirić, Tanja Čufer, Goran Gačevski, Marta Globočnik Kukovica, Kristina Gornik-Kramberger, Maja Ivanetič Pantar, Staša Jelerčič, Veronika Kloboves-Prevodnik, Mile Kovačević, Luka Ležaič, Mateja Marc-Malovrh, Katja Mohorčič, Bogdan Vidmar, Dušanka Vidovič, Gregor Vlačić, Ana Lina Vodušek, Rok Zbačnik, Ivana Žagar, 2020, strokovni članek Ključne besede: pljučni rak, priporočila
Objavljeno v DiRROS: 22.09.2020; Ogledov: 1894; Prenosov: 713
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120. Mycobacteria in aquarium fish : are fish handlers aware of their zoonotic potential?Mateja Pate, Andrej Ovca, Vlasta Jenčič, Marija Žolnir-Dovč, Matjaž Ocepek, 2019, izvirni znanstveni članek Ključne besede: fish tank granuloma, fish tuberculosis, mycobacteria, questionnaire, zoonosis
Objavljeno v DiRROS: 11.09.2020; Ogledov: 2113; Prenosov: 421
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