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Povzetek: Gross alpha and beta (GAB) measurements provide a rapid screening tool for assessing radionuclide contamination in water. This study aimed to establish a sensitive, simple method for low-level GAB detection using a liquid scintillation counter (LSC). Different sample preparation approaches (direct, co-precipitation with Fe(OH)3, Ca3(PO4)2, MnO2, and evaporation) were tested on four water samples containing natural and anthropogenic radionuclides from the IAEA 2022 proficiency test. Results, evaluated by recoveries and Zeta-scores, showed preparation methods influence recovery and quenching. Co-precipitation with Ca3(PO4)2 and evaporation performed best, though GAB remains a complementary rather than absolute analytical method, as not all radionuclides can be detected simultaneously.
Ključne besede: radioecology, gross alpha and beta, pre-concentration methods, liquid-scintillation counting, recovery, zeta-score
Objavljeno v DiRROS: 07.04.2026; Ogledov: 46; Prenosov: 29
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Povzetek: Background: A hemodialysis catheter may serve as a short- or medium-term vascular access solution. Current guidelines suggest restricting non-tunneled catheter use to 2 weeks, partially based on studies using straight non-tunneled jugular catheters, which have now been widely replaced with pre-curved catheters. We compared the rate of catheter-related blood stream infections (CRBSIs) and possible CRBSIs (PCRBSIs) of pre-curved non-tunneled and tunneled catheters in our hemodialysis center. Methods: This was a retrospective study including patients dialyzed on an outpatient basis between 1 January 2018 and 1 July 2024, with a follow-up until 1 March 2025. The primary aim was to compare the rates of CRBSIs. Results: In 301 patients, 625 non-tunneled single lumen catheter pairs and 53 double lumen tunneled catheters were used. There were 53 CRBSIs in non-tunneled and 10 in tunneled catheters, with identical incidence rate (0.48/1000 catheter-days in both groups). Analyzing CRBSIs and PCRBSIs together also showed similar infection rates [0.66 vs 0.58, incidence rate ratio (IRR) with 95% confidence interval 1.14 (0.6–2.1), P = .68]. Two subanalyses were made: CRBSI IRR in 27 patients with both types of catheters during study period was 1.37 (0.55–3.41, P = .49) and 2.01 (0.52–7.72, P = .47) in 36 patients after their first CRBSI. Time to CRBSI was also comparable in all analyses. Conclusions: Our study found no significant difference in the incidence of CRBSIs. We conclude that prolonged use of non-tunneled pre-curved catheters, which are easily managed, is a viable option for patients awaiting construction of arteriovenous fistula, insertion of a peritoneal catheter or kidney transplantation in a reasonable time. Promising results on long-term use from this study need to be confirmed in prospective studies.
Ključne besede: catheter-related blood stream infection, chronic hemodialysis, hemodialysis catheter, pre-curved jugular non-tunneled catheters, tunneled hemodialysis catheters
Objavljeno v DiRROS: 20.01.2026; Ogledov: 259; Prenosov: 219
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Povzetek: BackgroundSpinal muscular atrophy is a rare, genetic neuromuscular disorder. Disease-modifying therapies, when administered early, have shown improved outcomes, leading to the implementation of numerous newborn screening programs for spinal muscular atrophy. ObjectiveThe aim of this study was to evaluate the progress in implementing newborn screening for spinal muscular atrophy and therapy accessibility worldwide, after the first paper published in 2021. MethodsWe conducted a survey, contacted experts from 143 countries worldwide, gathered responses from 86 experts from 80 countries. ResultsBy 2023, 31 countries reported established programs, 33 in the beginning of the year 2024; identifying approximately 1176 cases of spinal muscular atrophy. Additionally, the availability of disease-modifying therapies has expanded. At least one therapy is now accessible in 62 countries. Challenges, such as lack of governmental support, resource constraints, and varying healthcare priorities continue to impede implementation in some countries. ConclusionsThe data shows a significant increase in the implementation of newborn screening programs since 2021. The experts are still expressing a strong need for equitable access to standard of care for all the patients globally. Despite all setbacks, collaborative efforts have played a crucial role in newborn screening for spinal muscular atrophy implementation and currently 7% of world newborns are being screened, projections indicate an estimated 18% screening rate by 2028
Ključne besede: newborn screening, spinal muscular atrophy, pre-symptomatic, nusinersen, risdiplam, onasemnogene abeparvovec
Objavljeno v DiRROS: 03.12.2025; Ogledov: 600; Prenosov: 208
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Povzetek: This dataset supports the tables and figures in the article Effect of sulfide in a 0.2 M NaCl solution on copper and pre-oxidized copper in oxic conditions Effect of sulfide in a 0.2 M NaCl solution on copper and pre-oxidized copper in oxic conditions (https://doi.org/10.1016/j.surfin.2025.107387). The data set contains experimental data for copper and pre-oxidized copper samples exposed to chloride solution (0.2 M Cl–) with different sulfide concentrations (5·10–6 M SH– and 1·10–4 M SH–) at room temperature (22 ± 2 °C) and elevated temperature (60 °C). Corrosion potential was monitored over a period of 24 hours. After 24 h immersion, electrochemical impedance spectroscopy was performed to observe the properties of the surface film formed on the copper and the pre-oxidized copper. The dataset also includes images of pre-oxidized samples after 24 hours immersion in different solutions, original Raman spectra and Raman images, XPS data and images data from the scanning electron microscope and images of cross-section of samples. The dataset was also used for the model of corroding system (Figure 13)
Ključne besede: copper, pre-oxidized copper, chloride and sulfide environment, electrochemical properties, surface characterization, Raman, cyclic voltammetry
Objavljeno v DiRROS: 11.08.2025; Ogledov: 786; Prenosov: 505
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Ključne besede: legumes, NIR, spectroscopy, plant genetic resources, pre-breeding collection, protein content, seed traits
Objavljeno v DiRROS: 25.02.2025; Ogledov: 1035; Prenosov: 585
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