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Iskalni niz: "avtor" (Nadja Triller) .

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Outcome of small cell lung cancer (SCLC) patients with brain metastases in a routine clinical setting
Mirko Lekić, Viljem Kovač, Nadja Triller, Lea Knez, Aleksander Sadikov, Tanja Čufer, 2012, izvirni znanstveni članek

Povzetek: Background. Small cell lung cancer (SCLC) represents approximately 13 tomediansurvival of SCLC patients treated by specific therapy (chemotherapy andžor radiotherapy) with regard to the 18%months in patients treated with standard chemotherapy and radiotherapy. Inpresence or absence of brain metastases at the time of diagnosis. Patients and methods. All SCLC patients have been treated in a routine clinical practice and followed up at theUniversity Clinic Golnik in Slovenia. In the retrospective study the medical files from 2002 to 2007 were review. All patients with cytological or histological confirmed disease and eligible for specific oncological treatment were included in the study. They have been treated according to the guidelines valid at the time. Chemotherapy and regular followed-up were carried out at the University Clinic Golnik and radiotherapy at the Institute of Oncology Ljubljana. Results. We found 251 patients eligible for the study. The median age of them was 65 years, majoritywere male (67%), smokers or ex-smokers (98%), with performance status 0 to 1 (83%). At the time of diagnosis no metastases were found in 64 patients(25.5%) and metastases outside the brain were presented in 153 (61.0%). Brain metastases, confirmedby a CT scan, were present in 34 patients (13.5%), most of them had also metastases at other localisations. (Abstract truncated at 2000 characters)
Ključne besede: pljuča, rak (medicina), drobnocelični rak, metastaze, možgani
Objavljeno v DiRROS: 22.03.2024; Ogledov: 81; Prenosov: 31
.pdf Celotno besedilo (552,38 KB)

Nrf2-interacting nutrients and COVID-19 : time for research to develop adaptation strategies
Jean Bousquet, Jean-Paul Cristol, Wienczyslawa Czarlewski, Josep M. Antò i Boquè, Adrian Martineau, Tari Haahtela, Susana C. Fonseca, Guido Iaccarino, Hubert Blain, Alessandro Fiocchi, Nisera Bajrović, Natalija Edelbaher, Maja Jošt, Peter Kopač, Anja Koren, Mitja Košnik, Karmen Kramer Vrščaj, Samo Kreft, Nika Lalek, Bojan Madjar, Tonka Poplas-Susič, Irma Rozman Sinur, Tanja Soklič, Katja Triller Vadnal, Nadja Triller, Jure Urbančič, Mihaela Zidarn, 2020, pregledni znanstveni članek

Povzetek: There are large between- and within-country variations in COVID-19 death rates. Some very low death rate settings such as Eastern Asia, Central Europe, the Balkans and Africa have a common feature of eating large quantities of fermented foods whose intake is associated with the activation of the Nrf2 (Nuclear factor (erythroid-derived 2)-like 2) anti-oxidant transcription factor. There are many Nrf2-interacting nutrients (berberine, curcumin, epigallocatechin gallate, genistein, quercetin, resveratrol, sulforaphane) that all act similarly to reduce insulin resistance, endothelial damage, lung injury and cytokine storm. They also act on the same mechanisms (mTOR: Mammalian target of rapamycin, PPAR[gamma]:Peroxisome proliferator-activated receptor, NF[kappa]B: Nuclear factor kappa B, ERK: Extracellular signal-regulated kinases and eIF2[alpha]:Elongation initiation factor 2[alpha]). They may as a result be important in mitigating the severity of COVID-19, acting through the endoplasmic reticulum stress or ACE-Angiotensin-II-AT1R axis (AT1R) pathway. Many Nrf2-interacting nutrients are also interacting with TRPA1 and/or TRPV1. Interestingly, geographical areas with very low COVID-19 mortality are those with the lowest prevalence of obesity (Sub-Saharan Africa and Asia). It is tempting to propose that Nrf2-interacting foods and nutrients can re-balance insulin resistance and have a significant effect on COVID-19 severity. It is therefore possible that the intake of these foods may restore an optimal natural balance for the Nrf2 pathway and may be of interest in the mitigation of COVID-19 severity.
Ključne besede: Covid-19, SARS-CoV-2, food, insulin resistance, obesity, Nrf2, nutrients, TRPA1
Objavljeno v DiRROS: 25.01.2021; Ogledov: 1626; Prenosov: 627
.pdf Celotno besedilo (1,61 MB)

Rak pljuč, klinični znaki, diagnostika in načini zdravljenja
Nadja Triller, 2012, objavljeni strokovni prispevek na konferenci

Objavljeno v DiRROS: 23.01.2020; Ogledov: 1619; Prenosov: 484
.pdf Celotno besedilo (103,72 KB)

Državni program obvladovanje raka in Klinika Golnik
Mitja Košnik, Tanja Čufer, Nadja Triller, 2011, objavljeni strokovni prispevek na konferenci

Ključne besede: Slovenija, državni programi, onkologija
Objavljeno v DiRROS: 17.09.2019; Ogledov: 2140; Prenosov: 573
.pdf Celotno besedilo (95,28 KB)

Naše izkušnje s citostatskim zdravljenjem drobnoceličnega pljučnega raka
Andrej Debeljak, Nadja Triller, Peter Kecelj, M... Šluga, 1998, objavljeni znanstveni prispevek na konferenci

Objavljeno v DiRROS: 17.09.2019; Ogledov: 2037; Prenosov: 567
.pdf Celotno besedilo (414,77 KB)

Paraneoplastični sindrom pri pljučnem raku
Nadja Triller, Andrej Debeljak, 1998, objavljeni znanstveni prispevek na konferenci

Objavljeno v DiRROS: 17.09.2019; Ogledov: 1963; Prenosov: 511
.pdf Celotno besedilo (282,30 KB)

Dispneja in kašelj
Nadja Triller, 2005, objavljeni strokovni prispevek na konferenci

Objavljeno v DiRROS: 17.09.2019; Ogledov: 1781; Prenosov: 442
.pdf Celotno besedilo (423,69 KB)

Celovita obravnava bolnika s pljučnim rakom na Kliniki Golnik
Nadja Triller, 2010, objavljeni strokovni prispevek na konferenci

Ključne besede: pljučni rak, celovita obravnava
Objavljeno v DiRROS: 17.09.2019; Ogledov: 2045; Prenosov: 519
.pdf Celotno besedilo (125,19 KB)

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