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Iskalni niz: "ključne besede" (aging) .

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1.
Variability in spatial and temporal gait dynamics during aging : a narrative review on the role of the neural system
Christoph Centner, Ramona Ritzmann, Uroš Marušič, Luke Hughes, 2026, pregledni znanstveni članek

Povzetek: Gait dynamics, encompassing both spatial and temporal parameters, undergo significant changes with aging, often leading to increased gait variability and, consequentially, a higher risk of falls. While cognitive and musculoskeletal factors have been demonstrated to contribute to these alterations, the role of the neural system is crucial and yet not fully understood. This review aims to synthesize the existing evidence on the age-related deterioration in locomotor functioning, with a specific emphasis on the neural mechanisms involved. Besides summarizing appropriate measures to quantify gait variability, several neural factors including cortical, neurotransmitter, and sensory system degeneration, are explored as key contributors to the observed changes in locomotion during aging. Additionally, the review discusses the potential use of diverse interventions to enhance gait variability during aging to reduce the risk of falls. By elucidating the complex interplay between aging, gait dynamics, and neural function, this review underscores the importance of targeted interventions aimed at preserving neural health to maintain gait stability and reduce fall risk in the aging population. The findings suggest that further research is needed to develop and refine strategies for the early detection and prevention of gait-related impairments linked to neural decline.
Ključne besede: gait, variability, aging, motor control
Objavljeno v DiRROS: 24.02.2026; Ogledov: 210; Prenosov: 108
.pdf Celotno besedilo (2,90 MB)
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2.
Predictors for residential mobility in later life : empirical findings for the young-oldliving in an Austrian small town
Tatjana Fischer, Markus Jobst, Karl Moder, 2025, izvirni znanstveni članek

Povzetek: The article addresses residential mobility in later life from the perspective of the young-old, an under-explored topic in Austria. Data originating from a written survey conducted as part of a cross-sectional case study on people aged 60 to 74 years living in an Austrian small town are used to estimate prospective behaviour using logistic regression. The results show that women and people with a higher educational attainment are more likely to leave their current urban residential municipality, while men are more likely to relocate to a nursing home. Moreover, a duration of residence of 20 or more years decreases the probability of relocation. The findings confirm previous studies and highlight, that more spatially disaggregated data is needed to improve decision-making in town planning.
Ključne besede: spatial research, cross-sectional study, aging in place, residental mobility, attitudes, Austria
Objavljeno v DiRROS: 10.02.2026; Ogledov: 449; Prenosov: 127
.pdf Celotno besedilo (4,71 MB)
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3.
Acceptance and perceptions of old age and aging
Mateja Lorber, 2019, predgovor, uvodnik, spremna beseda

Ključne besede: nurses, nursing care, health care, Slovenia, acceptance, elderly, older people, aging, Slovenia
Objavljeno v DiRROS: 28.01.2026; Ogledov: 266; Prenosov: 133
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4.
Dietary habits and physical activity patterns among Slovenian elderly : cross-sectional survey with cluster analysis
Joca Zurc, Cirila Hlastan-Ribič, Brigita Skela-Savič, 2015, izvirni znanstveni članek

Povzetek: Introduction: Physical activity and a healthy diet are significant predictors of healthy ageing-they help the elderly maintain their physical and mental health, and prevent chronic diseases. Methods: The data for the empirical quantitative survey were collected on the sample of 218 elderly community-dwelling participants (aged 65 years or more), using a structured questionnaire for self-reporting. Data analyses were proceed by the bivariate statistics, and multivariate hierarchical cluster analysis. Results: Most respondents reported good dietary habits (83.1 %) and a satisfactory physical activity level (60.5 %). On average, the elderly eat 3-4 meals per day (59.8 %) and engage in physical activity at least three times a week (58.6 %), with interventions lasting 15 minutes or more (84.4 %) and non-organized activities were prevailing (96.2 %). Ward's method yielded three clusters with homogenous dietary and physical activity patterns: 'Health Consciousness' (30.8 %), 'Being At Risk' (42.7 %) and 'Special Requirements' (26.5 %). Discussion and conclusion: In the future, special attention should be placed on the elderly group with special dietary and physical activity requirements. Additional studies on representative samples are required for a comprehensive investigation into the lifestyle behaviours of elderly individuals.
Ključne besede: lifestyle, elderly, aging factors, health promotion, cluster analysis
Objavljeno v DiRROS: 28.01.2026; Ogledov: 222; Prenosov: 106
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Effect of deep cryogenic treatment on aging behavior and properties of Al-Mg-Si alloy
Bojan Podgornik, Matic Klug Jovičević, Patricia Jovičević Klug, 2023, objavljeni znanstveni prispevek na konferenci

Ključne besede: deep cryogenic treatment, Al-Mg-Si alloy, aging, microstructure, hardness, fatigue
Objavljeno v DiRROS: 08.07.2025; Ogledov: 519; Prenosov: 285
.pdf Celotno besedilo (425,38 KB)
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7.
Investigating aquatic biodegradation and changes in the properties of pristine and UV-irradiated microplastics from conventional and biodegradable agricultural plastics
Ula Putar, Aida Fazlić, Lukas Brunnbauer, Janja Novak, Anita Jemec Kokalj, Jernej Imperl, Jiří Kučerík, Petra Procházková, Stefania Federici, Rachel Hurley, Andrijana Sever Škapin, Pavlína Modlitbová, Pavel Pořízka, Jozef Kaiser, Andreas Limbeck, Gabriela Kalčíková, 2025, izvirni znanstveni članek

Povzetek: There is an increasing tendency to replace conventional agricultural plastic mulching films with biodegradable alternatives. However, while the latter biodegrade well under controlled conditions (e.g. industrial compost), their biodegradation in non-target environments (e.g. aquatic environments) is questioned and poorly understood. Therefore, in this study, microplastics derived from conventional polyethylene (PE) and biodegradable polybutylene adipate terephthalate starch blend (PBAT) mulching films were exposed to UV irradiation and subsequently tested for their ready biodegradability in an aqueous medium where changes in their characteristics were evaluated. The results showed limited biodegradation for pristine and UV-aged PE: no morphological, surface chemical or internal changes were observed. Pristine PBAT showed signs of initial biodegradation, while UV-aged PBAT biodegraded by up to 57%. New functional groups appeared on the PBAT surface after UV irradiation according to FTIR analysis and crystallinity increased after biodegradation. Elemental analysis revealed a range of metals in PE and PBAT microplastics. No changes in metal distribution analysed in microplastic after UV-aging or biodegradation were found, except that less titanium was present in PBAT after biodegradation indicating potential leaching. None of the PBAT microplastics had ecotoxic effects towards the aquatic plant Lemna minor. Pristine and UV-aged PE showed negative effects on roots, but these were not observed after biodegradation. Low biodegradation of pristine PBAT and possible leaching of metals demonstrated here raise questions about the sustainable use of biodegradable alternatives, especially when they enter non-target environments.
Ključne besede: microplastics, biodegradable plastics, aging, biodegradation, ecotoxicity, leaching
Objavljeno v DiRROS: 27.05.2025; Ogledov: 829; Prenosov: 576
.pdf Celotno besedilo (6,56 MB)
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8.
Maristem - stem cells of marine/aquatic invertebrates : from basic research to innovative applications
Loriano Ballarin, Baruch Rinkevich, Kestin Bartscherer, Artur Burzynski, Sebastien Cambier, Matteo Cammarata, Isabelle Domart-Coulon, Damjana Drobne, Juanma Encinas, Uri Frank, Anne-Marie Geneviere, Bert Hobmayer, Helike Löhelaid, Daniel Lyons, Pedro Martinez, Paola Oliveri, Lorena Perić, Stefano Piraino, Andreja Ramšak, Sebastian Rakers, Fabian Rentzsch, Amalia Rosner, Tiago Henriques da Silva, Ildiko Somorjai, Sherif Suleiman, Ana Varela Coelho, 2018, izvirni znanstveni članek

Povzetek: The “stem cells” discipline represents one of the most dynamic areas in biomedicine. While adult marine/aquatic invertebrate stem cell (MISC) biology is of prime research and medical interest, studies on stem cells from organisms outside the classical vertebrate (e.g., human, mouse, and zebrafish) and invertebrate (e.g., Drosophila, Caenorhabditis) models have not been pursued vigorously. Marine/aquatic invertebrates constitute the largest biodiversity and the widest phylogenetic radiation on Earth, from morphologically simple organisms (e.g., sponges, cnidarians), to the more complex mollusks, crustaceans, echinoderms, and protochordates. These organisms contain a kaleidoscope of MISC-types that allow the production of a large number of novel bioactive-molecules, many of which are of significant potential interest for human health. MISCs further participate in aging and regeneration phenomena, including whole-body regeneration. For years, the European MISC-community has been highly fragmented and has established scarce ties with biomedical industries in an attempt to harness MISCs for human welfare. Thus, it is important to (i) consolidate the European community of researchers working on MISCs; (ii) promote and coordinate European research on MISC biology; (iii) stimulate young researchers to embark on research in MISC-biology; (iv) develop, validate, and share novel MISC tools and methodologies; (v) establish the MISC discipline as a forefront interest of biomedical disciplines, including nanobiomedicine; and (vi) establish collaborations with industries to exploit MISCs as sources of bioactive molecules. In order to fill the recognized gaps, the EC-COST Action 16203 “MARISTEM” has recently been launched. At its initial stage, the consortium unites 26 scientists from EC countries, Cooperating countries, and Near Neighbor Countries.
Ključne besede: aging, bioactive molecules, blue biotechnology, cancer, cell culture, COST Action, Europe, marine/aquatic invertebrates, regeneration, stem cells
Objavljeno v DiRROS: 24.07.2024; Ogledov: 1434; Prenosov: 746
.pdf Celotno besedilo (1015,21 KB)
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9.
Evidence for senescence in survival but not in reproduction in a short-lived passerine
Rémi Fay, Michael Schaub, Jennifer A. Border, Ian G. Henderson, Georg Fahl, Jürgen Feulner, Petra Horch, Mathis Müller, Helmut Rebstock, Dmitry Shitikov, Davorin Tome, Matthias Vögeli, Martin U. Grüebler, 2020, izvirni znanstveni članek

Povzetek: Senescence has been studied since a long time by theoreticians in ecology and evolution, but empirical support in natural population has only recently been accumulating. One of the current challenges is the investigation of senescence of multiple fitness components and the study of differences between sexes. Until now, studies have been more frequently conducted on females than on males and rather in long-lived than in short-lived species. To reach a more fundamental understanding of the evolution of senescence, it is critical to investigate age-specific survival and reproduction performance in both sexes and in a large range of species with contrasting life histories. In this study, we present results on patterns of age-specific and sex-specific variation in survival and reproduction in the whinchat Saxicola rubetra, a short-lived passerine. We compiled individual-based long-term datasets from seven populations that were jointly analyzed within a Bayesian modeling framework. We found evidence for senescence in survival with a continuous decline after the age of 1 year, but no evidence of reproductive senescence. Furthermore, we found no clear evidence for sex effects on these patterns. We discuss these results in light of previous studies documenting senescence in short-lived birds. We note that most of them have been conducted in populations breeding in nest boxes, and we question the potential effect of the nest boxes on the shape of age-reproductive trajectories.
Ključne besede: actuarial senescence, age-specific demographic rate, aging, Saxicola rubetra, whinchat
Objavljeno v DiRROS: 22.07.2024; Ogledov: 871; Prenosov: 535
.pdf Celotno besedilo (619,48 KB)
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10.
Multisensory mechanisms of gait and balance in Parkinson's disease : an integrative review
Stiven Roytman, Rebecca Paalanen, Giulia Carli, Uroš Marušič, Prabesh Kanel, Teus van Laar, Nicolaas I. Bohnen, 2025, pregledni znanstveni članek

Povzetek: Understanding the neural underpinning of human gait and balance is one of the most pertinent challenges for 21st-century translational neuroscience due to the profound impact that falls and mobility disturbances have on our aging population. Posture and gait control does not happen automatically, as previously believed, but rather requires continuous involvement of central nervous mechanisms. To effectively exert control over the body, the brain must integrate multiple streams of sensory information, including visual, vestibular, and somatosensory signals. The mechanisms which underpin the integration of these multisensory signals are the principal topic of the present work. Existing multisensory integration theories focus on how failure of cognitive processes thought to be involved in multisensory integration leads to falls in older adults. Insufficient emphasis, however, has been placed on specific contributions of individual sensory modalities to multisensory integration processes and cross-modal interactions that occur between the sensory modalities in relation to gait and balance. In the present work, we review the contributions of somatosensory, visual, and vestibular modalities, along with their multisensory intersections to gait and balance in older adults and patients with Parkinson's disease. We also review evidence of vestibular contributions to multisensory temporal binding windows, previously shown to be highly pertinent to fall risk in older adults. Lastly, we relate multisensory vestibular mechanisms to potential neural substrates, both at the level of neurobiology (concerning positron emission tomography imaging) and at the level of electrophysiology (concerning electroencephalography). We hope that this integrative review, drawing influence across multiple subdisciplines of neuroscience, paves the way for novel research directions and therapeutic neuromodulatory approaches, to improve the lives of older adults and patients with neurodegenerative diseases.
Ključne besede: aging, gait, balance, encephalography, functional magnetic resonance imaging, multisensory integration
Objavljeno v DiRROS: 17.06.2024; Ogledov: 8160; Prenosov: 954
.pdf Celotno besedilo (1,36 MB)
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