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Iskalni niz: "avtor" (Jan Grosek) .

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Safety of simultaneous robot-assisted resection of colorectal malignancy and synchronous liver metastases
Miha Petrič, Boštjan Plešnik, Jurij Aleš Košir, Blaž Trotovšek, Jan Grosek, 2026, izvirni znanstveni članek

Povzetek: Introduction: Simultaneous resection of primary colorectal malignancies and liver metastases resulted in outcomes comparable to those achieved through a two-stage procedure, while offering the advantage of a single surgical intervention. The role of the robotic approach remains underexplored because of the lack of comprehensive evidence. The objective of our study was to examine the safety of the robotic surgical platform, assess its short-term outcomes, and compare them with those of open procedures. Methods and Material: We retrospectively analyzed data from an initial small series of eight consecutive patients treated at the UMC Ljubljana between March 2023 and December 2025. These patients underwent robot-assisted simultaneous resection of colorectal malignancies and liver metastases. Their outcomes were compared with those of an open cohort of eight patients. Results: The median operative time was 334 min (range, 193–415 min). No conversions or transfusions were required. Three patients experienced severe complications, accounting for 37.5% of the cohort. The median duration of hospitalization was 9.5 days. The median number of lymph nodes retrieved was 22. Complete (R0) resection of the primary tumor was achieved in all cases (100%), whereas resection of the liver was achieved in 87.5% of the cases. Importantly, there were no instances of re-hospitalization within 30 days or mortality within 90 days. Conclusions: Although the rate of severe complications is relatively high, the robotic surgical platform allows for the safe simultaneous resection of colorectal malignancies and liver metastases, achieving short-term outcomes comparable to those of open surgery.
Ključne besede: simultaneous resection, colorectal malignancy, liver metastases, minimally invasive surgery
Objavljeno v DiRROS: 01.04.2026; Ogledov: 184; Prenosov: 114
.pdf Celotno besedilo (402,57 KB)
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Single-docking robot-assisted radical antegrade modular pancreatosplenectomy with partial left nephrectomy in a patient with synchronous pancreatic neuroendocrine neoplasm and clear cell renal cell carcinoma
Miha Petrič, Manca Bregar, Jan Grosek, Aleš Tomažič, Simon Hawlina, 2026, drugi znanstveni članki

Povzetek: The synchronous occurrence of pancreatic neuroendocrine neoplasm (PNEN) and clear cell renal cell carcinoma (ccRCC) in one patient is extremely rare. Synchronous resection of both tumours is preferred over a two-stage procedure if possible. The robotic da Vinci Xi platform allows for multi-quadrant surgery with oncological outcomes comparable to those of laparoscopic or open surgery. We present the case report of an 80-year-old male who underwent synchronous resection of a PNEN in the tail of the pancreas and ccRCC in the left kidney. To the best of our knowledge, this is the first case report on this topic.
Ključne besede: clear cell renal cell carcinoma, neuroendocrine neoplasm of the pancreas, partial nephrectomy, RAMPS, robot-assisted surgery
Objavljeno v DiRROS: 23.03.2026; Ogledov: 194; Prenosov: 144
.pdf Celotno besedilo (772,00 KB)
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6.
Robot-assisted lateral pancreaticojejunostomy in a patient with chronic pancreatitis and history of liver transplantation
Boštjan Plešnik, Jan Grosek, Blaž Trotovšek, Aleš Tomažič, Miha Petrič, 2026, drugi znanstveni članki

Povzetek: A 52‑year‑old female patient with a history of liver transplantation due to alcoholic liver cirrhosis presented with persistent post‑prandial pain, leading to substantial weight loss of 16 kg. The findings of contrast‑enhanced computed tomography were consistent with the diagnosis of chronic pancreatitis, and endoscopic treatment provided no functional improvement. The patient was scheduled for a robot‑assisted lateral pancreaticojejunostomy which was performed after initial lysis of adhesions from her prior liver transplantation. The procedure was completed safely using the robotic da Vinci Xi platform in 180 min, with an estimated blood loss of 300 mL. During the post‑operative course, anaemia was noted and treated with a blood transfusion, and the patient was discharged on the post‑operative day 4. The patient fully recovered without post‑prandial pain and began regaining weight 1 month after the procedure. To the best of our knowledge, this is the first report of a successful robot‑assisted lateral pancreaticojejunostomy following prior liver transplantation.
Ključne besede: robotic surgery, lateral pancreaticojejunostomy, chronic pancreatitis, liver transplantation
Objavljeno v DiRROS: 16.03.2026; Ogledov: 242; Prenosov: 160
.pdf Celotno besedilo (863,06 KB)
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7.
Intraoperative fluorescence angiography with indocyanine green to prevent anastomotic leak in rectal cancer surgery (IntAct) : an unblinded randomised controlled trial
David Jayne, Julie Croft, Neil Corrigan, Philip Quirke, Ronan A Cahill, Gemma Ainsworth, David M Meads, 2025, izvirni znanstveni članek

Povzetek: Background: Data are mixed on whether indocyanine green (ICG) fluorescence angiography can reduce the high rate of anastomotic leaks in patients undergoing surgery for rectal cancer. Therefore, we aimed to investigate the safety and efficacy of ICG fluorescence angiography in reducing the rate of clinical anastomotic leaks in these patients. Methods: IntAct was an unblinded randomised controlled trial conducted at 28 specialist rectal cancer centres across eight European countries. Adults (≥18 years) with rectal cancer (lower margin of cancer ≤15 cm from the anal verge) medically fit for elective, curative, laparoscopic or robotic high or low anterior resection were eligible. Patients not undergoing colorectal or anal anastomosis and those with synchronous colonic tumours or recurrent or locally advanced rectal cancer requiring extended or multi-visceral excision were excluded. Eligible participants were randomly assigned (1:1) by use of minimisation with a random element to undergo surgery with or without ICG (standard care). Resections and anastomoses were done per surgeon preference. In the ICG group, surgeons first marked proximal transection levels via standard white-light laparoscopy and then administered an intravenous bolus of 0·1 mg/kg of ICG for perfusion assessment. A second 0·1 mg/kg ICG assessment was done following anastomosis. In the standard care group, only a white-light assessment of bowel perfusion was performed. The primary endpoint was the rate of clinical anastomotic leak (grades B or C, per the International Study Group of Rectal Cancer) within 90 postoperative days. Analyses were done in the intention-to-treat population for complete cases. This trial is registered with the ISRCTN registry (ISRCTN13334746) and is now complete. Findings: Between Oct 20, 2017, and Aug 15, 2023, 2534 patients were assessed for eligibility and 766 participants were randomly assigned (383 to the ICG group and 383 to the standard care group). 501 (65%) of 766 participants were male, 726 (95%) were of White ethnicity, and the median age was 64·0 years (IQR 56·0–72·0). 343 patients in the ICG group and 355 in the standard care group were included in the intention-to-treat analysis. The rates of anastomotic leak were 11 (3%) of 343 in the ICG group and 20 (6%) in the standard care group for grade A, 11 (3%) and 31 (9%) for grade B, and 25 (7%) and 23 (6%) for grade C. Within 90 days, a clinical anastomotic leak occurred in 90 (13%) of 698 participants: 36 (10%) of 343 in the ICG group and 54 (15%) of 355 in the standard care group (adjusted odds ratio 0·667 [95% CI 0·419–1·060]; p=0·087). There were no serious adverse events related to ICG. Interpretation: Although IntAct did not show a significant benefit for ICG fluorescence angiography, a signal towards a reduction in clinical anastomotic leak rate was observed. The benefit of ICG could be in preventing grade A or B leaks, given similar rates of grade C leaks between groups. Future research is needed to standardise ICG fluorescence assessment and understand its relevance to anastomotic leak.
Ključne besede: intraoperative fluorescence angiography with indocyanine, rectal cancer, surgery
Objavljeno v DiRROS: 10.03.2026; Ogledov: 270; Prenosov: 213
.pdf Celotno besedilo (281,09 KB)
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8.
Robotic right hemicolectomy for persistent colocutaneous fistula following laparoscopic appendectomy : a case report
Ana Kalamutova, Jurij Aleš Košir, Jurij Janež, Jan Grosek, 2025, drugi znanstveni članki

Povzetek: The article presents a case report of a patient who was referred to our hospital after laparoscopic appendectomy with severalrevisions, resulting in a persistent colocutaneous fistula to the hepatic flexure. After preoperative planning, a robotic righthemicolectomy was performed. The patient was discharged on postoperative day 7 with no postoperative complications.We concluded that robot-assisted colectomy after preoperative patient management can be performed as an effectivetechnique for colocutaneous fistula treatment with the benefits of minimal invasive surgery, including reduced postoperativepain, early patient mobilization, and shorter hospital stay
Ključne besede: colocutaneous fistula, robotic surgery, colorectal surgery, robotic colectomy
Objavljeno v DiRROS: 10.03.2026; Ogledov: 242; Prenosov: 209
.pdf Celotno besedilo (1,19 MB)
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9.
Intraluminal migration of a surgical drain near an anastomosis site after total gastrectomy : a case report
Jurij Janež, Jan Romih, Žan Čebron, Aleksandar Gavrić, Samo Plut, Jan Grosek, 2025, drugi znanstveni članki

Povzetek: Background: Esophagojejunal anastomotic leakage (EJAL) is a severe complication following gastrectomy for gastric cancer, typically treated with drainage and nutritional support. We report a case of intraluminal drain migration near the esophagojejunal anastomosis (EJA), resulting in persistent drainage and mimicking EJAL after total gastrectomy. Case summary: A 64-year-old male underwent open total gastrectomy with Roux-en-Y reconstruction for gastric adenocarcinoma, with two silicone drains placed near the EJA. On postoperative day (POD) 4, the patient developed signs of peritonitis and sepsis, necessitating surgical re-exploration abscess drainage, peritoneal lavage, and drain repositioning. A contrast swallow study on POD 18 revealed rapid filling of the abdominal drain without extraluminal contrast collection. Persistent drainage prompted an upper gastrointestinal endoscopy on POD 59, which revealed approximately 5 cm of the drain within the esophagus, with the perforation site located 2 cm distal to the intact EJA. The drain was repositioned under endoscopic guidance. A repeat contrast radiograph on POD 67 demonstrated no evidence of extraluminal contrast extravasation or filling of the abdominal drain. The patient was subsequently discharged without further incident. Conclusion: Intraluminal drain migration is a rare complication following gastric surgery but should be considered when persistent drainage occurs.
Ključne besede: surgical drain, gastrectomy
Objavljeno v DiRROS: 16.01.2026; Ogledov: 314; Prenosov: 249
.pdf Celotno besedilo (3,88 MB)
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10.
Robotske kolorektalne resekcije
Jurij Aleš Košir, Jan Grosek, 2025, objavljeni povzetek strokovnega prispevka na konferenci

Ključne besede: onkološka kirurgija, kolorektalna kirurgija, robotska kirurgija
Objavljeno v DiRROS: 07.01.2026; Ogledov: 565; Prenosov: 235
.pdf Celotno besedilo (9,79 MB)
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