1321. Geochemical and mineralogical approaches in unraveling paleoweathering, provenance, and tectonic setting of the clastic sedimentary succession (Western Central Paratethys)Kristina Ivančič, Rok Brajkovič, Mirijam Vrabec, 2024, izvirni znanstveni članek Povzetek: Pronounced tectonic and paleogeographic changes were detected in the Alpine–Pannonian region during the Miocene at the interface between the Alps, the Dinarides, and the Pannonian Basin. To understand the major tectonic, paleogeographic, and paleoclimatic changes during this period, geochemical and mineralogical investigations were carried out on the fine-grained clastic sedimentary rocks in the Tunjice Hills. The paleoweathering indicates a cold and/or arid to a warm and humid period. The paleoclimate and the regional climatic conditions correspond well with the Middle Miocene Climatic Optimum. The mineral composition shows an abundance of quartz and calcite. Quartz is associated with detrital origin from volcanic and metamorphic rocks of the Eastern and Southern Alps and with authigenic processes in sediments. Calcite is related to authigenic origin formed in shallow marine environments and to detrital provenance from the Southern Alps. Not all discriminant functions based on major oxides provided adequate results in determining the tectonic setting. The source rocks were subjected to oceanic island arc and collision. Moreover, sedimentation was influenced by both active and passive margin settings. The former is related to the Alpine collision, which continued from the Cenozoic onward, and the latter is connected to the processes associated with the formation of the Pannonian Basin System, which began in the late Early Miocene.
Ključne besede: Central Paratethys, provenance, tectonic setting, paleoweathering, Miocene, Tunjice Hills
Objavljeno v DiRROS: 15.01.2024; Ogledov: 234; Prenosov: 65
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1322. High rate of complications in patients with carcinoma of the cervix surgically treated after radical radiotherapyAlbert-Peter Fras, 1995, izvirni znanstveni članek Povzetek: With the aim to improve the results of treatment of patients who had advanced carcinoma of the uterine cervix and were radically irradiated, a group of 49 patients underwent hysterectomy two to 24 months after completion of radiotherapy, among whom for only 43 patients data were available. Radiotherapy consisted of 40 Gy external beam irradiation to true pelvis, low dose intracavitary treatment to a total dose 40 Gy to point A, and parametrial irradiation 16 to 20 Gy, shielding the place where radioactive sources were positioned during intracavitary therapy. Necrosis, persistent cervical carcinoma, recurrent carcinoma, and in patients younger than 50 years no evidence of disease (NED) with dysplasia were indications for the surgical treatment. Hysterectomy with bilateral oophorectomy was as conservative as possible but severe complications, such as ureteral stenosis (five cases), recto-vaginal fistula (three cases), vesico-vaginal fistula (two cases), recto-vesico-vaginal fistula (one case) occurred. Asymptomatic frozen pelvs as a mild complication occurered in 10 cases. One patient died postoperatively because of dehiscence and abdominal wall necrosis. In 17 (39.5%) of 43 patients complications occurred, although asymtomatic frozen pelvic was not taken in account. We believe that such a combined treatment is only for selected cases.
Ključne besede: Complications
Objavljeno v DiRROS: 15.01.2024; Ogledov: 199; Prenosov: 58
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1324. Electrochemotherapy with bleomycin : The first clinical experience in malignant melanoma patientsZvonimir Rudolf, Borut Štabuc, Maja Čemažar, Damijan Miklavčič, Lojze Vodovnik, Gregor Serša, 1995, izvirni znanstveni članek Ključne besede: melanoma therapy, bleomycin, electric stimulation therapy
Objavljeno v DiRROS: 15.01.2024; Ogledov: 279; Prenosov: 60
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1325. Improved therapeutic effect of electrochemotherapy with cisplatin by intratumoral drug administration and changing of electrode orientation for electropermeabilization on EAT tumor model in miceMaja Čemažar, Damijan Miklavčič, Lojze Vodovnik, Tomaž Jarm, Zvonimir Rudolf, Borut Štabuc, Tanja Čufer, Gregor Serša, 1995, izvirni znanstveni članek Ključne besede: neoplasmas, experimental therapy, cisplatin, electric stimulation therapy, cell membrane permeability
Objavljeno v DiRROS: 15.01.2024; Ogledov: 215; Prenosov: 62
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