211. Assessing the impact of waste co-incineration at the Anhovo cement plant (Slovenia) on the regional cancer burden*Vesna Zadnik, Mojca Birk, Teja Oblak, Maja Jurtela, Sonja Tomšič, Katarina Lokar, Ana Mihor, Nika Bric, Miran Mlakar, Amela Duratović Konjević, Tina Žagar, 2025, izvirni znanstveni članek Povzetek: This epidemiological study aims to assess the cancer risk potentially associated with environmental exposure resulting from cement production and waste co-incineration at the Anhovo cement plant in Western Slovenia and to develop a strong and reliable methodological framework for the long-term surveillance of environmentally related cancer risks in small geographical areas. Materials and methods We integrated all the available data sources: cancer cases from the population-based Slovenian Cancer Registry; background population; and available measurements on exposure to air PM10 particles and chromium (Cr) in the soil in the municipality of Kanal and the wider Goriška region. Relative risks of cancer in small geographical areas were estimated using Bayesian hierarchical spatial models and the population attributable fractions of the modelled risk factors were calculated. The point source analysis compared the cancer risk near the cement plant to that in more distant areas. Results The analysis did not reveal any excess cancer incidence in the area of the Anhovo cement plant or an association with the PM10 particles and Cr in the soil. The incidence of mesothelioma remains high in the region, but stable in the last two decades. Conclusions In view of the environmental pollution caused by either historical cement production or the potential impact of current waste co-incineration activities in Kanal, we strongly recommend that a follow-up epidemiological study be carried out in the next 10 to 20 years. The methodological framework established in the present study provides a foundation for the ongoing surveillance of the cancer burden in the region.
Ključne besede: cancer incidence, environmental exposure, cancer data
Objavljeno v DiRROS: 05.12.2025; Ogledov: 70; Prenosov: 0 |
212. Načrtovanje komunikacijske strategije za obstoječi in nove presejalne programe za raka v SlovenijiSara Atanasova, 2025, objavljeni znanstveni prispevek na konferenci Povzetek: Slovenija se sooča z načrtovanimi spremembami v obstoječem Državnem programu zgodnjega odkrivanja predrakavih sprememb materničnega vratu (ZORA) ter s pripravo novih organiziranih presejalnih programov za raka prostate (PETER) in pljučnega raka (LUKA). Uvajanje sprememb na področju presejalnih programov za raka predstavlja kompleksen javnozdravstveni izziv, ki zahteva premišljeno komunikacijsko podporo. Brez ustrezno zasnovane komunikacijske strategije obstaja tveganje neustreznega razumevanja sprememb, nizke udeležbe ciljnih populacij ter pomanjkanja podpore med zdravstvenimi delavci in drugimi deležniki. Namen prispevka je osvetliti ključne korake pri načrtovanju komunikacijske strategije, kot so situacijska analiza in analiza deležnikov, opredelitev strateških ciljev, identifikacija ciljnih skupin in segmentacija populacije oz. občinstva, oblikovanje glavnih sporočil in stališč, identifikacija ključnih komunikacijskih kanalov in strateških pristopov, načrtovanje implementacije strategije, evalvacija in merjenje učinkovitosti strategije. Prispevek obravnava, kako lahko raziskave in empirični podatki služijo kot temelj za oblikovanje ciljno usmerjenih strategij, ki bodo učin- kovito podprle spremembe v omenjenih presejalnih programih. Projekt Cancer screening awareness in Slovenia – Communication strategy, ki ga financira Mednarodna agencija za raziskovanje raka, bo s kvalitativnimi in kvantitativnimi raziskavami zagotovil vpoglede v zaznave in stališča ciljnih populacij in zdravstvenih strokovnjakov. Na tej osnovi bodo oblikovana priporočila za komunikacijske strategije, prilagojene posameznim presejalnim programom, kar bo lahko prispevalo k njihovi večji legitimnosti, sprejetosti in dolgoročni trajnosti.
Ključne besede: komuniciranje, komunikacijska strategija
Objavljeno v DiRROS: 05.12.2025; Ogledov: 73; Prenosov: 26
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213. Projekt : priprava epidemioloških podlag za uvedbo novih nacionalnih presejalnih programov za raka v SlovenijTina Žagar, Teja Oblak, Ana Mihor, Barbara Mihevc Ponikvar, Maja Jurtela, Mojca Birk, Nika Bric, Sonja Tomšič, Katarina Lokar, Miran Mlakar, Amela Duratović Konjević, Katja Kolenc, Vesna Zadnik, 2025, objavljeni znanstveni prispevek na konferenci Ključne besede: epidemiologija raka, presejalni programi, onkologija
Objavljeno v DiRROS: 05.12.2025; Ogledov: 78; Prenosov: 31
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216. Glyoxal as single crosslinker for mechanically blown, condensed and hydrolyzable tannin foamsJonas Eckardt, Michele De Nato, Elena Colusso, Lorenzo Moro, Primož Šket, Samuele Giovando, Gianluca Tondi, 2025, izvirni znanstveni članek Objavljeno v DiRROS: 05.12.2025; Ogledov: 81; Prenosov: 54
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220. Comparison of vaginal prostaglandin E2 delivery system versus expectant management in term premature rupture of membranes : a andomized controlled trialBlaž Pavič, Polona Pečlin, 2025, izvirni znanstveni članek Povzetek: Background: Premature rupture of the membranes (PROM) occurring after the 37th week of gestation, prior to the onset of regular contractions, affects approximately 8% of pregnancies and typically leads to the spontaneous onset of labor. A prolonged interval between PROM and delivery increases the risk of maternal infection and early neonatal sepsis. This prospective, randomized study aimed to assess the efficacy, safety, and maternal satisfaction associated with the use of a vaginal prostaglandin E2 (PGE2) delivery system compared to expectant management approach following PROM. Methods: Term pregnant women with a singleton cephalic presentation, who experienced PROM within 4–12 hours and had an unripe cervix, were randomized into 2 groups. The intervention group received labor induction using a slow-release 10 mg dinoprostone (PGE2) vaginal delivery system, whereas the control group underwent expectant management. If active labor had not commenced within 24 hours of enrollment, labor was induced with oxytocin in both groups. Results: In this prospective randomized study, 74 pregnant women with PROM after the 37th week of gestation, prior to before the onset of active labor, were enrolled. Active labor began within 24 hours after enrollment in 54% of the control group and 77% of the intervention group (p = 0.036). The intervention group had a 3.42-hour shorter interval from randomization to delivery; however, this difference was not statistically significant (p = 0.067). When analyzing time to spontaneous vaginal delivery, administration of PGE2 in the intervention group was associated with a 4.3-hour reduction in delivery time (p = 0.029). There was no statistically significant difference regarding mode of delivery between the groups, with 6% of cesarean section in the intervention group vs. 15% in the control group (p = 0.343). No significant differences were observed between the groups in oxytocin use, labor complication rates, neonatal outcomes, or participant satisfaction. Notably, in a significant proportion of participants (37%) in the intervention group, the vaginal PGE2 delivery system was unintentionally expelled prior to the onset of active labor. Conclusion:The slow-release PGE2 vaginal system reduced the time from randomization to the onset of active labor and to vaginal delivery in pregnant women after PROM, without impacting the mode of delivery maternal and neonatal complications rates, or satisfaction rate compared to expectant management approach. Early induction of labor following PROM with a PGE2 vaginal system represents an effective and safe alternative to expectant labor management.
Ključne besede: premature rupture of membranes, PROM, induction of labor, prostaglandin E2 vaginal system, dinoprostone
Objavljeno v DiRROS: 04.12.2025; Ogledov: 137; Prenosov: 55
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