Iskanje po repozitoriju

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Ključne besede: texture analysis, ultrasonography, tendinosis
Objavljeno v DiRROS: 25.07.2024; Ogledov: 124; Prenosov: 55
Celotno besedilo (898,52 KB)

Objavljeno v DiRROS: 25.07.2024; Ogledov: 108; Prenosov: 44
Celotno besedilo (675,76 KB)

Povzetek: Background. The aim of the study was to derive and compare metabolic parameters relating to benign and ma- lignant pulmonary nodules using dynamic 2-deoxy-2-[fluorine-18]fluoro-D-glucose (18F-FDG) PET/CT, and nodule perfu- sion parameters derived through perfusion computed tomography (CT). Patients and methods. Twenty patients with 21 pulmonary nodules incidentally detected on CT underwent a dynamic 18F-FDG PET/CT and a perfusion CT. The maximum standardized uptake value (SUVmax) was measured on conventional 18F-FDG PET/CT images. The influx constant (Ki) was calculated from the dynamic 18F-FDG PET/CT data using Patlak model. Arterial flow (AF) using the maximum slope model and blood volume (BV) using the Patlak plot method for each nodule were calculated from the perfusion CT data. All nodules were characterized as malignant or benign based on histopathology or 2 year follow up CT. All parameters were statistically compared between the two groups using the nonparametric Mann-Whitney test. Results. Twelve malignant and 9 benign lung nodules were analysed (median size 20.1 mm, 9-29 mm) in 21 patients (male/female = 11/9; mean age +- SD: 65.3 +- 7.4; age range: 50-76 years). The average SUVmax values +- SD of the benign and malignant nodules were 2.2 +- 1.7 vs. 7.0 +- 4.5, respectively (p = 0.0148). Average Ki values in benign and malig- nant nodules were 0.0057 +- 0.0071 and 0.0230 +- 0.0155 min-1, respectively (p = 0.0311). Average BV for the benign and malignant nodules were 11.6857 +- 6.7347 and 28.3400 +- 15.9672 ml/100 ml, respectively (p = 0.0250). Average AF for the benign and malignant nodules were 74.4571 +- 89.0321 and 89.200 +- 49.8883 ml/100g/min, respectively (p = 0.1613). Conclusions. Dynamic 18F-FDG PET/CT and perfusion CT derived blood volume had similar capability to differentiate benign from malignant lung nodules.
Ključne besede: CT perfusion, malignant pulmonary nodules, benign pulmonary nodules
Objavljeno v DiRROS: 22.07.2024; Ogledov: 143; Prenosov: 54
Celotno besedilo (707,02 KB)

Povzetek: Background. RCC accounts for only 2-3% of all cancers. Due to its non-specific symptoms disease is often diagnosed in advanced stage. Disseminated RCC frequently produces bone metastases that are almost always highly destructive, hyper vascularized and purely osteolytic. Case report. In this article we describe a case of a 71-year old male patient with disseminated osteoblastic bone metastases from renal cell carcinoma (RCC), and present a short review of published literature reporting cases of osteoblastic bone metastases from RCC. Our patient presented with thoracic pain aggravated by movement. He was diagnosed with predominantly osteoblastic bone metastases in the skeleton of thoracic and lumbar vertebra along with metastases in iliac bones, ribs, humerus and clavicles. Initially, origin of bone metastases was unknown, but later a small tumor in patients right kidney was identified. Microscopic evaluation of the open bone biopsy showed clear cell RCC with sarcomatoid differentiation. Conclusions. Although, due to its rarity, RCC is not included in the primary differential diagnosis in patients with osteoblastic metastases, such rare cases suggest that RCC may be considered in the diagnosis when there no other primary tumor is found.
Objavljeno v DiRROS: 11.04.2024; Ogledov: 355; Prenosov: 93
Celotno besedilo (758,62 KB)

Povzetek: Background. This paper presents imaging diagnostics of an aneurysm of the aorta, indications, common contraindications and measurements for the construction and selection of an endoprosthesis. The examination using ultrasound is the most handy and economically justifiable method for detectingan aneurysm of the aorta, for monitoring asymptomatic aneurysm as well as patients having undergone an operation or those with an endoprosthesis. Another examination to visualise the aortic aneurysm is CT with or without contrastive medium. The plan for treating an aneurysm can be made with the help of a DSA, helical CT angiography and/or MRA. DSA shows wellthe lightness of the aneurysm and the aorta, as well as the changes insideof it, large arteries close to the aneurysm and the condition of pelvic arteries for the selection of the approach. The helical CT angiography and MRAin two or three dimensional reproduction in several directions enable an accurate measurement of an aneurysm, the aorta diameter above and below the aneurysm, and the evaluation of the quality of its wall. Conclusions. The indication areas for endoprosthesis are aneurysm of the abdominal aorta and those of the descending part of thoracic aorta. The treatment with endoprosthesis as a less invasive method is indicated in patients who risk a number of complications and even mortality when treated surgically. Endoprosthesis is made of metal stent and prosthesis. The stent attaches the endoprosthesis to the unaffected part of the aorta above and below the aneurysm, it sets the stent asunder and provides support. The prosthesis is made of Dacron synthetic fabric, which has very good properties for this purpose such as small compliance, porosity, permeability and extensibility. The endoprosthesis is introduced into the aorta through a catheter system withthe help of a special guide wire. The entering point is surgically opened common femoral or iliac artery.
Objavljeno v DiRROS: 24.01.2024; Ogledov: 398; Prenosov: 99
Celotno besedilo (323,00 KB)