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33. Study of radiation induced changes of phosphorus metabolism in mice by ▫$^{31}P$▫ NMR spectroscopyIgor Serša, Simona Kranjc Brezar, Gregor Serša, Alenka Nemec Svete, Bojan Ložar, Ana Sepe, Jernej Vidmar, Marjeta Šentjurc, 2010, izvirni znanstveni članek Objavljeno v DiRROS: 15.03.2024; Ogledov: 162; Prenosov: 42
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34. Genetic markers in oligodendroglial tumoursTomaž Velnar, Uroš Smrdel, Mara Popović, Gorazd Bunc, 2010, pregledni znanstveni članek Povzetek: Background. Oliogodendrogliomas are brain tumours composed of the cells resembling oligodendrocytes. They represent the third most common glial tumour, comprising 2.5% of all primary brain tumours and 5-20% of all gliomas. Conclusions. Oligodendroglial tumours with 1p and 19q loss demonstrate a better overall prognosis due to more indolent clinical behaviour and higher sensitivity to treatment. Additionally, 1p and 19q loss is a marker of clinical utility, helping to assess tumour sensitivity to chemotherapy and harbouring the potential for improving the diagnosis and survival of oligodendroglioma patients as well as future clinical practice.
Objavljeno v DiRROS: 15.03.2024; Ogledov: 142; Prenosov: 35
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39. Targeted gene therapy in radiotherapyUrška Kamenšek, Gregor Serša, 2008, pregledni znanstveni članek Povzetek: The dramatic pace in development of gene therapy over the past decades has made it a realistic alternative for the treatment of cancer. Radiotherapy, on the other hand, is one of the most commonly used and well established cancer treatment modalities. The latest improvements in the physical targeting ability of radiotherapy and understanding of the molecular mechanism involved in the cellular response to ionizing radiation have presented an opportunity to combine radiotherapy with gene therapy. This review article will focus on gene therapy strategies that can be used to enhance the effectiveness of radiotherapy, with an emphasis on transcriptional targeting approaches.
Objavljeno v DiRROS: 07.03.2024; Ogledov: 178; Prenosov: 46
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40. Treatment of condensation in sandwich panels without known vapour resistance of sealantGregor Vidmar, 2020, objavljeni znanstveni prispevek na konferenci Povzetek: In order to calculate amount of interstitial condensation in a building envelope, water vapour resistance of each layer is of importance. Once having it, 1D calculation according to ISO 13788 with monthly average vapour pressures can be applied. In EN 14509 sandwich panels are considered to be impermeable for water vapour, thus (according to the standard) water vapour cannot enter from outside and condensate in the panels. But it is not always true for real sandwich panels, because joints between neighbouring panels can cause non-neglecting water vapour bridges. Although in measurements of linear water vapour transmittance of the joints (Ψv) stationary boundary vapour pressures can be applied, the measurements can be long lasting. We shortened time needed to get Ψv performing simulations in Delphin6.0. We simulated panels and steel sheets with joints using constant boundary vapour pressures and compared the results with the results of measurements on the equivalent systems.
In systems under consideration a sealant in built-in-state, located at a joint of a sandwich panel, is a compressed EPDM tube. It is impossible to directly measure its effective μ according to ISO 12572. In the paper we study to which precision it is possible to determine it using measurements and simulations. Once having effective μ of the sealant (if all other necessary material parameters available) one can simulate condensation in envelopes including sandwich panels in 2D according to EN 15026 using hourly climatic data. Another goal of the study was determination of differences in resulting Ψv values when varying narrowest part of the gap dGAP at the joint in the panels without any sealant. Results confirm significant sensibility of Ψv to variations of dGAP.
Ključne besede: water vapour condensation, water vapour diffusion, numerical simulations, water vapour resistance, linear water vapour transmittance, sendwich panels
Objavljeno v DiRROS: 05.03.2024; Ogledov: 209; Prenosov: 116
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