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Na voljo sta dva načina iskanja: enostavno in napredno. Enostavno iskanje lahko zajema niz več besed iz naslova, povzetka, ključnih besed, celotnega besedila in avtorja, zaenkrat pa ne omogoča uporabe operatorjev iskanja. Napredno iskanje omogoča omejevanje števila rezultatov iskanja z vnosom iskalnih pojmov različnih kategorij v iskalna okna in uporabo logičnih operatorjev (IN, ALI ter IN NE). V rezultatih iskanja se izpišejo krajši zapisi podatkov o gradivu, ki vsebujejo različne povezave, ki omogočajo vpogled v podroben opis gradiva (povezava iz naslova) ali sprožijo novo iskanje (po avtorjih ali ključnih besedah).

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1631 - 1640 / 2000
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1631.
Compensational role between cathepsins
Urša Pečar Fonović, Janko Kos, Ana Mitrović, 2024, pregledni znanstveni članek

Povzetek: Cathepsins, a family of lysosomal peptidases, play a crucial role in maintaining cellular homeostasis by regulating protein turnover and degradation as well as many specific regulatory actions that are important for proper cell function and human health. Alterations in the activity and expression of cathepsins have been observed in many diseases such as cancer, inflammation, neurodegenerative disorders, bone remodelling-related conditions and others. These changes are not exclusively harmful, but rather appear to be a compensatory response on the lack of one cathepsin in order to maintain tissue integrity. The upregulation of specific cathepsins in response to the inhibition or dysfunction of other cathepsins suggests a fine-tuned system of proteolytic balance and understanding the compensatory role of cathepsins may improve therapeutic potential of cathepsin's inhibitors. Selectively targeting one cathepsin or modulating their activity could offer new treatment strategies for a number of diseases. This review emphasises the need for comprehensive research into cathepsin biology in the context of disease. The identification of the specific cathepsins involved in compensatory responses, the elucidation of the underlying molecular mechanisms and the development of targeted interventions could lead to innovative therapeutic approaches.
Ključne besede: lysosomal peptidases, compensation, bone resorption
Objavljeno v DiRROS: 23.05.2024; Ogledov: 351; Prenosov: 245
.pdf Celotno besedilo (730,45 KB)
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1632.
Koprivni kaneloni : kuharski recepti
Jernej Javornik, 2024, poljudni članek

Ključne besede: kulinarični recepti
Objavljeno v DiRROS: 23.05.2024; Ogledov: 478; Prenosov: 50
.pdf Celotno besedilo (315,24 KB)

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Screening of metal reduction potential for thermochemical hydrogen storage
Jure Voglar, Blaž Likozar, 2024, izvirni znanstveni članek

Objavljeno v DiRROS: 22.05.2024; Ogledov: 384; Prenosov: 288
.pdf Celotno besedilo (1,13 MB)
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1636.
Neutral and selective processes shape MHC diversity in roe deer in Slovenia
Elena Bužan, Sandra Potušek, Luka Duniš, Boštjan Pokorny, 2022, izvirni znanstveni članek

Ključne besede: major histocompatibility complex, MHC genes, immunogenetics, Capreolus capreolus
Objavljeno v DiRROS: 22.05.2024; Ogledov: 422; Prenosov: 244
.pdf Celotno besedilo (1,25 MB)
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1637.
Catalytic hydrogenation reaction micro-kinetic model for dibenzyltoluene as liquid organic hydrogen carrier
Aleksandra Tomić, Brett Pomeroy, Branislav Todić, Blaž Likozar, Nikola Nikačević, 2024, izvirni znanstveni članek

Objavljeno v DiRROS: 21.05.2024; Ogledov: 447; Prenosov: 974
.pdf Celotno besedilo (3,07 MB)
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