31. Quality-assurance of heat-flow data: the new structure and evaluation scheme of the IHFC Global Heat Flow DatabaseSven Fuchs, Ben Norden, Florian Neumann, Norbert Kaul, Akiko Tanaka, Ilmo T. Kukkonen, Christophe Pascal, Rodolfo Christiansen, Gianluca Gola, Dušan Rajver, 2023, izvirni znanstveni članek Povzetek: Since 1963, the International Heat Flow Commission has been fostering the compilation of the Global Heat Flow Database to provide reliable heat-flow data. Over time, techniques and methodologies evolved, calling for a reorganization of the database structure and for a reassessment of stored heat-flow data. Here, we provide the results of a collaborative, community-driven approach to set-up a new, quality-approved global heat-flow database. We present background information on how heat-flow is determined and how this important thermal parameter could be systematically evaluated. The latter requires appropriate documentation of metadata to allow the application of a consistent evaluation scheme. The knowledge of basic data (name and coordinates of the site, depth range of temperature measurements, etc.), details on temperature and thermal-conductivity data and possible perturbing effects need to be given. The proposed heat-flow quality evaluation scheme can discriminate between different quality aspects affecting heat flow: numerical uncertainties, methodological uncertainties, and environmental effects. The resulting quality codes allow the evaluation of every stored heat-flow data entry. If mandatory basic data are missing, the entry is marked accordingly. In cases where more than one heat-flow determination is presented for one specific site, and all of them are considered for the site, the poorest evaluation score is inherited to the site level. The required data and the proposed scheme are presented in this paper. Due to the requirements of the newly developed evaluation scheme, the database structure as presented in 2021 has been updated and is available in the appendix of this paper. The new quality scheme will allow a comprehensible evaluation of the stored heat-flow data for the first time.
Ključne besede: heat-flow density, quality scheme, thermal geophysics, global heat flow database (GHFD), thermal parameter, data information system, International Heat Flow Commission (IHFC)
Objavljeno v DiRROS: 09.08.2023; Ogledov: 502; Prenosov: 188
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32. Integrating geological data in Europe to foster multidisciplinary researchMarc Urvois, Sylvain Grellet, Henning Lorenz, Rainer Haener, Christelle Loiselet, Matthew Harrison, Matija Krivic, Christian Brogaard Pedersen, Marianne B. Wiese, Amelia Baptie, Martin Nayembil, James Trench, Ivor Marsh, Carlo Cipolloni, Chiara d'Ambrogi, Maria Pia Congi, 2022, izvirni znanstveni članek Povzetek: This paper presents novel data discovery and integration, facilitated using borehole logging information with on-demand web services to produce 3D geological structures. This domain interoperability across EPOS was created for the purpose of research, but it is also highly relevant for the response to societal grand challenges such as natural hazards and climate change. European and international interoperability implementation frameworks are well described and used (e.g., INSPIRE, ISO, OGC, and IUGS/CGI). It can be difficult for data providers to deploy web services that support the full semantic data definition (e.g., OGC Complex Feature) to expose several millions of geological entities through web-enabled data portals as required by pan-European projects.
Ključne besede: EPOS, geological information, borehole, FAIR, linked data
Objavljeno v DiRROS: 19.07.2023; Ogledov: 539; Prenosov: 181
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33. PyPore3D : an open source software tool for imaging data processing and analysis of porous and multiphase mediaAmal Aboulhassan, Francesco Brun, George Kourousias, Gabriele Lanzafame, Marco Voltolini, Adriano Contillo, Lucia Mancini, 2022, izvirni znanstveni članek Povzetek: In this work, we propose the software library PyPore3D, an open source solution for data processing of large 3D/4D tomographic data sets. PyPore3D is based on the Pore3D core library, developed thanks to the collaboration between Elettra Sincrotrone (Trieste) and the University of Trieste (Italy). The Pore3D core library is built with a distinction between the User Interface and the backend filtering, segmentation, morphological processing, skeletonisation and analysis functions. The current Pore3D version relies on the closed source IDL framework to call the backend functions and enables simple scripting procedures for streamlined data processing. PyPore3D addresses this limitation by proposing a full open source solution which provides Python wrappers to the the Pore3D C library functions. The PyPore3D library allows the users to fully use the Pore3D Core Library as an open source solution under Python and Jupyter Notebooks PyPore3D is both getting rid of all the intrinsic limitations of licensed platforms (e.g., closed source and export restrictions) and adding, when needed, the flexibility of being able to integrate scientific libraries available for Python (SciPy, TensorFlow, etc.).
Ključne besede: tomographic 3D/4D imaging data, image processing and analysis, open source software, Python
Objavljeno v DiRROS: 28.04.2023; Ogledov: 675; Prenosov: 254
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34. Geographical variation in abdominal colour pattern in Criorhina pachymera (Egger, 1858) (Diptera: Syrphidae)Jan Bisschop, Maarten De Groot, Gaël Pétremand, 2023, izvirni znanstveni članek Povzetek: The bee-mimicking hoverfly species Criorhina pachymera shows pronounced geographical variation in abdominal colour pattern. Based on 218 records from 22 European countries, we describe six abdomen forms divided over two main groups. Group A in western, northern and central parts of Europe contains abdomen forms A1–A3 with slender pollinose bands on the third and fourth tergite. Group B in south-eastern Europe contains forms B1–B3 with broad pollinose bands. These groups are separated by the Alps and the Carpathians, such as the separation of the original distributions of the two main postglacial recolonization lineages of honey bees in Europe. As these honey bee groups differ by the width of the pollinose bands on the third to fifth tergite, Batesian mimicry can explain the group distribution of C. pachymera with slender or broad pollinose bands. The different forms of C. pachymera in both groups are categorised by the extent of orange colouration on the second and third tergite. The darkest form A1, has a widespread distribution in Europe. Intermediate bright forms A2 and A3 occur predominantly in a belt along the southern margin of the group A distribution and in Sweden. Dark form B1 and intermediate bright form B2 occur on the Balkan peninsula and in neighbouring regions. The brightest form B3, is found in Italy, Switzerland (Ticino) and Greece. There is an average increase in the extent of orange colouration on the second and third tergite with decreasing geographical latitude, making temperature a likely additional cause for the described abdominal colour variation.
Ključne besede: hoverflies, colour variation, biogeography, Batesian mimicry, citizen science data
Objavljeno v DiRROS: 28.03.2023; Ogledov: 803; Prenosov: 316
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35. Gene sequence variation data for the publication "Synchronous effective population size changes and genetic stability of forest trees through glacial cycles" : version 1.0Tanja Pyhäjärvi, Francesca Bagnoli, Katharina Budde, Stephen Cavers, Sandra Cervantes, Benjamin Dauphin, Bruno Fady, Patricia Faivre-Rampant, Santiago C. González-Martínez, Delphine Grivet, Felix Gugerli, Véronique Jorge, Chedly Kastallya, Martin Lascoux, Isabelle Lesur Kupin, Pascal Milesi, Dario I. Ojeda, Sanna Olsson, Lars Opgenoorth, Sara Pinosio, Christophe Plomion, Christian Rellstab, Odile Rogier, Simone Scalabrin, Ivan Scotti, Giovanni G Vendramin, Marjana Westergren, 2023, zaključena znanstvena zbirka raziskovalnih podatkov Povzetek: This dataset contains the gene sequence variation data (vcf files and their tbi index files) of seven forest tree species used in the manuscript "Synchronous effective population size changes and genetic stability of forest trees through glacial cycles". For each species, between 411 and 651 genotyped trees are included, sampled across Europe in at least 20 locations. Several versions are provided. Species included: Pinus sylvestris, Picea abies, Fagus sylvatica, Populus nigra, Quercus petraea, Pinus pinaster, Betula pendula
Ključne besede: gene sequence, variation data, data set
Objavljeno v DiRROS: 07.03.2023; Ogledov: 774; Prenosov: 795
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36. Landslide monitoring techniques in the Geological Surveys of EuropeMateja Jemec Auflič, Gerardo Herrera, Rosa María Mateos, Eleftheria Poyiadji, Lídia Quental, Bernardie Severine, Tina Peternel, Laszlo Podolszki, Stefano Calcaterra, Arben Kociu, Bartłomiej Warmuz, Jan Jelének, Kleopas Hadjicharalambous, Gustaf Peterson Becher, Claire Dashwood, Peter Ondrus, Vytautas Minkevičius, Saša Todorović, Jens Jørgen Møller, Jordi Marturia, 2023, pregledni znanstveni članek Povzetek: Landslide monitoring is a mandatory step in landslide risk assessment. It requires collecting data on landslide conditions (e.g., areal extent, landslide kinematics, surface topography, hydrogeometeorological parameters, and failure surfaces) from different time periods and at different scales, from site-specific to local, regional, and national, to assess landslide activity. In this analysis, we collected information on landslide monitoring techniques from 17 members of the Earth Observation and Geohazards Expert Group (from EuroGeoSurveys) deployed between 2005 and 2021. We examined the types of the 75 recorded landslides, the landslide techniques, spatial resolution, temporal resolution, status of the technique (operational, non-operational), time of using (before the event, during the event, after the event), and the applicability of the technique in early warning systems. The research does not indicate the accuracy of each technique but, rather, the extent to which Geological Surveys conduct landslide monitoring and the predominant techniques used. Among the types of landslides, earth slides predominate and are mostly monitored by geological and engineering geological mapping. The results showed that Geological Surveys mostly utilized more traditional monitoring techniques since they have a broad mandate to collect geological data. In addition, this paper provides new insights into the role of the Geological Surveys on landslide monitoring in Europe and contributes to landslide risk reduction initiatives and commitments (e.g., the Kyoto Landslide Commitment 2020).
Ključne besede: landslide, monitoring techniques, geological data, Geological Surveys of Europe
Objavljeno v DiRROS: 30.01.2023; Ogledov: 721; Prenosov: 294
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37. The primary and secondary mineral resources of Montenegro and their mapping into the European data modelSlobodan Radusinović, Robert Šajn, Božica Jovanović, Duška Rokavec, Katarina Hribernik, Vasilije Abramović, Matej Draksler, Ivan Danilović, Mia Jovanović, 2022, izvirni znanstveni članek Povzetek: Primary and secondary mineral resources are of strategic importance to the EU economy. Montenegro, as a country candidate for membership in the EU, is required to follow (and later to implement) European policies, strategies as well as initiatives, including those related to mineral resources and the mining sector. The importance of providing access to mineral raw materials in the future is recognized by the EU, as well as meeting the needs of European industry, maintaining employment and ensuring further development. Considering the overall economic situation in Montenegro, it is important to encourge the mining sector and other industries based on the use of mineral resources in making a greater contribution to the development and sustainability of society as a whole and also increase the share of national GDP.
The potential for discovery and utilization of primary and secondary mineral resources in Montenegro is demonstrated. The most important metallic mineral resources are bauxite, lead and zinc, while conventional energy resources include coal (oil and gas potential has yet to be proven). In addition, there are abundant non-metallic mineral raw materials - industrial minerals and construction materials.
Secondary mineral resources, especially aluminous red mud (bauxite residue), are also significant and have been the subject of research in recent years. Tailings from flotation processes at operating and abandoned lead and zinc mines might also be of interest for metal recovery. Bottom and flay ash from thermal power plants, slag from steel production, as well as marlstone and limestone from the hanging wall of coal deposits may also have potential. Waste rocks could be used particularly for secondary aggregate production.
A database was developed and the most important deposits of primary and secondary mineral resources in Montenegro were mapped during the RESEERVE project. Mineral data were harmonised so as to be INSPIRE compliant. In addition, some novel geochemical exploration results of secondary mineral resources are presented.
Ključne besede: primary and secondary mineral resources, Montenegro, RESEERVE project, European geological data platform (EGDI), INSPIRE
Objavljeno v DiRROS: 16.11.2022; Ogledov: 613; Prenosov: 235
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38. A data-driven machine learning approach for brain-computer interfaces targeting lower limb neuroprostheticsArnau Dillen, Elke Lathouwers, Aleksandar Miladinović, Uroš Marušič, Fakhreddine Ghaffari, Olivier Romain, Romain Meeusen, Kevin De Pauw, 2022, izvirni znanstveni članek Povzetek: Prosthetic devices that replace a lost limb have become increasingly performant in recent years. Recent advances in both software and hardware allow for the decoding of electroencephalogram (EEG) signals to improve the control of active prostheses with brain-computer interfaces (BCI). Most BCI research is focused on the upper body. Although BCI research for the lower extremities has increased in recent years, there are still gaps in our knowledge of the neural patterns associated with lower limb movement. Therefore, the main objective of this study is to show the feasibility of decoding lower limb movements from EEG data recordings. The second aim is to investigate whether well-known neuroplastic adaptations in individuals with an amputation have an influence on decoding performance. To address this, we collected data from multiple individuals with lower limb amputation and a matched able-bodied control group. Using these data, we trained and evaluated common BCI methods that have already been proven effective for upper limb BCI. With an average test decoding accuracy of 84% for both groups, our results show that it is possible to discriminate different lower extremity movements using EEG data with good accuracy. There are no significant differences (p = 0.99) in the decoding performance of these movements between healthy subjects and subjects with lower extremity amputation. These results show the feasibility of using BCI for lower limb prosthesis control and indicate that decoding performance is not influenced by neuroplasticity-induced differences between the two groups.
Ključne besede: neuroprosthetics, brain-computer interface, machine learning, electroencephalography, data-driven learning, lower limb amputation
Objavljeno v DiRROS: 21.07.2022; Ogledov: 710; Prenosov: 529
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39. Real-world experience with capmatinib in MET exon 14-mutated non-small cell lung cancer (RECAP) : a retrospective analysis from an early access programOliver Illini, Hannah Fabikan, Aurélie Swalduz, Anders Vikström, Dagmar Krenbek, Michael Schumacher, Elizabeth Dudnik, Michael Studnicka, Ronny Öhman, Robert Wurm, Tanja Čufer, Katja Mohorčič, Maximilian J Hochmair, 2022, izvirni znanstveni članek Povzetek: Background: Patients with non-small cell lung cancer (NSCLC) presenting with mesenchymal–epithelial transition (MET) exon 14 skipping mutation have an unfavorable prognosis with standard treatments. Capmatinib is a selective MET inhibitor, which showed promising efficacy in this patient population in early trials. Methods: We performed a retrospective, international, multicenter efficacy and safety analysis in patients with NSCLC treated with capmatinib in an early access program between March 2019 and December 2021. Results: Data from 81 patients with advanced MET exon 14 mutated NSCLC treated with capmatinib in first- or later-line therapy were analyzed. Median age was 77years (range, 48–91), 56% were women, 86% had stage IV disease, and 27% had brain metastases. For all patients, the objective response rate (ORR) to capmatinib was 58% (95% CI, 47–69), whereas it was 68% (95% CI, 50–82) in treatment-naïve and 50% (95% CI, 35–65) in pretreated patients. The median progression-free survival was 9.5months (95% CI, 4.7–14.3), whereas it was 10.6months (95% CI, 5.5–15.7) in first-line and 9.1months (95% CI, 3.1–15.1) in pretreated patients. After a median follow-up of 11.0months, the median overall survival was 18.2 months (95% CI, 13.2–23.1). In patients with measurable brain metastases (n=11), the intracranial ORR was 46% (95% CI, 17–77). Capmatinib showed a manageable safety profile. Grade⩾3 treatment-related adverse events included peripheral edema (13%), elevated creatinine (4%), and elevated liver enzymes (3%). Conclusion: In patients with MET exon 14 skipping mutation, capmatinib showed durable systemic and intracranial efficacy and a manageable safety profile. This analysis confirms previously reported phase II data in a real-world setting.
Ključne besede: non-small cell lung carcinoma -- drug therapy -- genetics, molecular targeted therapy, real-world data, capmatinib, targeted therapy
Objavljeno v DiRROS: 24.06.2022; Ogledov: 940; Prenosov: 675
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40. Behavioural patterns in allergic rhinitis medication in Europe : a study using 28 MASK-air® real-world dataBernardo Sousa-Pinto, Ana Sá-Sousa, Rafael José Vieira, Rita Amaral, Ludger Klimek, Wienczyslawa Czarlewski, Josep M. Antò i Boquè, Oliver Pfaar, Anna Bedbrook, Mihaela Zidarn, Joao A. Fonseca, Jean Bousquet, 2022, izvirni znanstveni članek Povzetek: Background. Co-medication is common among patients with allergic rhinitis (AR), but its dimension and patterns are unknown. This is particularly relevant since AR is understood differently across European countries, as reflected by rhinitis-related search patterns in Google Trends. This study aims to assess AR co-medication and its regional patterns in Europe, using real-world data. Methods. We analysed 2015-2020 MASK-air® European data. We compared days under no medication, monotherapy, and co-medication using the visual analogue scale (VAS) levels for overall allergic symptoms (“VAS Global Symptoms”) and impact of AR on work. We assessed the monthly use of different medication schemes, performing separate analyses by region (defined geographically or by Google Trends patterns). We estimated the average number of different drugs reported per patient within one year. Results. We analysed 222,024 days (13,122 users), including 63,887 days (28.8%) under monotherapy, and 38,315 (17.3%) under co-medication. The median “VAS Global Symptoms” was 7 for no medication days, 14 for monotherapy and 21 for co-medication (p<0.001). Medication use peaked during the spring, with similar patterns across different European regions (defined geographically or by Google Trends). Oral H1-antihistamines were the most common medication in single and co-medication. Each patient reported using an annual average of 2.7 drugs, with 80% reporting two or more. Conclusions. AR medication patterns are similar across European regions. One third of treatment days involved co-medication. These findings suggest that patients treat themselves according to their symptoms (irrespective of how they understand AR), and that co-medication use is driven by symptom severity.
Ključne besede: asthma -- drug therapy, rhinitis -- drug therapy, allergic rhinitis -- drug therapy, visual analogue scale, histamine antagonists, antihistamines, behavioural patterns, medication patterns, real-world data
Objavljeno v DiRROS: 14.03.2022; Ogledov: 858; Prenosov: 301
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