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1472. Advances in the management of craniopharyngioma in children and adultsMojca Jensterle Sever, Sončka Jazbinšek, Roman Bošnjak, Mara Popović, Lorna Zadravec-Zaletel, Tina Vipotnik-Vesnaver, Barbara Faganel Kotnik, Primož Kotnik, 2019, pregledni znanstveni članek Povzetek: Childhood and adult-onset craniopharyngioma is a rare embryogenic tumor of the sellar, suprasellar, and parasellar region. Survival rates are high; however, tumor location and treatment sequalae including endocrine deficits, visual impairment, metabolic complications, cognitive and psychosocial deficits can significantly impair patient%s quality of life. There is considerable controversy regarding the optimal management of craniopharyngiomas. Subtotal resection of the tumor followed by targeted irradiation to avoid further hypothalamic damage is currently indicated. Novel insights in the tumor%s molecular pathology present the possibility for targeted therapy possibly decreasing the rate and severity of treatment-associated morbidity. Conclusions. Craniopharyngioma should be seen as a chronic disease. To achieve optimal outcomes a multidisciplinary team of specialized neurosurgeons, neuro-radiologists, neuro-oncologists, pathologists and endocrinologists should be involved in the diagnosis, planning of the surgery, irradiation and long-term follow-up.
Ključne besede: craniopharyngioma, hypopituitarism, metabolic syndrome
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1473. Diagnostic accuracy of haemophilia early arthropathy detection with ultrasound (HEAD-US) : a comparative magnetic resonance imaging (MRI) studyDomen Plut, Barbara Faganel Kotnik, Irena Preložnik Zupan, Damjana Ključevšek, Gaj Vidmar, Žiga Snoj, Carlo Martinoli, Vladka Salapura, 2019, izvirni znanstveni članek Ključne besede: haemophilia, haemophilic arthropathy, magnetic resonance imaging
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1478. The use of high-frequency short bipolar pulses in cisplatin electrochemotherapy in vitroMaria Scuderi, Matej Reberšek, Damijan Miklavčič, Janja Dermol-Černe, 2019, izvirni znanstveni članek Ključne besede: electroporation, electrochemotherapy, high-frequency bipolar pulses, cisplatin, cell survival, drug uptake
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