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Povzetek: Background. Image cytometry can measure numerous nuclear features which could be considered a surrogate end-point marker of molecular genetic changes in a nucleus. The aim of the study was to analyze image cytometric nuclear featuresin paired samples of primary tumor and neck metastasis in patients with inoperable carcinoma of the head and neck. Materials and methods. Image cytometric analysis of cell suspensions prepared from primary tumor tissue andfine needle aspiration biopsy cell samples of neck metastases from 21 patients treated with concomitant radiochemotherapy was performed. Nuclear features were correlated with clinical characteristics and response to therapy. Results. Manifestation of distant metastases and new primaries was associated (p<0.05) with several chromatin characteristics from primary tumor cells, whereas the origin of index cancer and disease response in the neck wasrelated to those in the cells from metastases. Many nuclear features of primary tumors and metastases correlated with the TNM stage. Conclusions. A specific pattern of correlation between well-established prognostic indicatorsand nuclear features of samples from primary tumors and those from neck metastases was observed. Image cytometric nuclear features represent a promising candidate marker for recognition of biologically different tumor subgroups.
Objavljeno v DiRROS: 19.03.2024; Ogledov: 182; Prenosov: 51
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Povzetek: Shallow geothermal energy (SGE) is a renewable energy that could contribute to the decarbonatization of the heating and cooling sector. SGE is predominantly harnessed through ground source heat pump (GSHP) systems. The choice of which type of GSHP system depends on various factors. Understanding these factors is crucial for optimizing the efficiency of GSHP systems and fostering their implementation. In this paper, we have analysed the spatial distribution of GSHPs in Slovenia. We identified 1073 groundwater and 1122 ground-coupled heat pump systems with a total heat pump capacity of almost 30 MW. We quantitatively assessed the influence of geological, hydrogeological, and climate conditions on their spatial distribution. Using the χ2 test and information value method, we identified hydrogeological conditions as the most influential factor for the GSHP systems’ spatial distribution. We also performed the spatial analysis of geological and hydrogeological data in 22 European countries, including Slovenia. We collected the reported numbers of installed GSHP units in 2020 and were able to distinguish the shares of groundwater and ground-coupled heat pump systems for 12 of these countries. The analysis showed that ground-coupled heat pumps predominate in most countries, even if the natural conditions are favourable for groundwater heat pumps.
Ključne besede: shallow geothermal energy, renewable heating and cooling, ground-source heat pump, spatial distribution, natural condition
Objavljeno v DiRROS: 19.03.2024; Ogledov: 207; Prenosov: 90
Celotno besedilo (15,39 MB)

Povzetek: Direct-co-direct product $G\circledast H$ of graphs $G$ and $H$ is a graph on the vertex set $V(G)\times V(H)$. Two vertices $(g,h)$ and $(g',h')$ are adjacent if $gg'\in E(G)$ and $hh'\in E(H)$ or $gg'\notin E(G)$ and $hh'\notin E(H)$. We show that if at most one factor of $G\circledast H$ is connected, then the distance between two vertices of $G\circledast H$ is bounded by three unless some small number of exceptions. All the exceptions are completely described which yields the distance formula.
Ključne besede: direct-co-direct product, distance, eccentricity, disconnected graphs
Objavljeno v DiRROS: 19.03.2024; Ogledov: 200; Prenosov: 91
Celotno besedilo (450,88 KB)
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Povzetek: Background. Pseudoaneurysms are rare complications of myocardial infarction with propensity for rupture. There is still a challenge with which diagnostic imaging we performed a final diagnosis of pseudoaneurysm and differentiate it from true aneurysm what is clinically important due to the different treatment. Case report. We presented the unusual case of a 56-year-old man with signs of decompensated heart failure which had worsened a few months before hospitalization. We believed that during worsening of symptoms the patient suffered a silent myocardial infarction complicated by subacute free wall rupture which resulted into left ventricular pseudoaneurysm formation without tamponade. Echocardiography showed dilatativecardiomyopathy which was already present years before and a very rare location of the left ventricular pseudoaneurysm on the anterolateral part of the left ventricle. Pseudoaneurysm was confirmed with CT scan. Due to the severity of contractile dysfunction and no response in treatment for congestive heart failure the directive for the resection was tempered and the patient died due to the progressive heart failure and embolic phenomena. Conclusions. This report shows the importance of non-invasive imaging diagnostic evaluation of acute decompensated heart failure where echocardiography and chest X-ray are the first diagnostic steps. Based on those findings further imaging diagnostic steps must be performed such as CT scan in our case which finally confirms left ventricular pseudoaneurysm with dilatative cardiomyopathy.
Objavljeno v DiRROS: 19.03.2024; Ogledov: 172; Prenosov: 84
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Povzetek: The complementary prism of a graph $\Gamma$ is the graph $\Gamma \overline{\Gamma}$, which is formed from the union of $\Gamma$ and its complement $\overline{\Gamma}$ by adding an edge between each pair of identical vertices in $\Gamma$ and $\overline{\Gamma}$. Vertex-transitive self-complementary graphs provide vertex-transitive complementary prisms. It was recently proved by the author that $\Gamma \overline{\Gamma}$ is a core, i.e. all its endomorphisms are automorphisms, whenever $\Gamma$ is vertex-transitive, self-complementary, and either $\Gamma$ is a core or its core is a complete graph. In this paper the same conclusion is obtained for some other classes of vertex-transitive self-complementary graphs that can be decomposed as a lexicographic product $\Gamma = \Gamma_1 [\Gamma_2]$. In the process some new results aboutthe homomorphisms of a lexicographic product are obtained.
Ključne besede: graph homomorphism, core, complementary prism, self-complementary graph, vertex-transitive graph, lexicographic product
Objavljeno v DiRROS: 19.03.2024; Ogledov: 172; Prenosov: 92
Celotno besedilo (411,68 KB)
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