371. Slovenian national food consumption survey in adolescents, adults and elderly : external scientific reportMatej Gregorič, Urška Blaznik, Nataša Delfar, Metka Zaletel, Darja Lavtar, Barbara Koroušić-Seljak, Petra Golja, Katja Zdešar Kotnik, Igor Pravst, Nataša Fidler Mis, Stojan Kostanjevec, Majda Pajnkihar, Tamara Poklar Vatovec, Ada Hočevar-Grom, 2019, končno poročilo o rezultatih raziskav Ključne besede: Slovenia, food consumption survey, dietary intake, adults, adolescents, elderly, EU Menu
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372. Extracellular vesicle-derived bioactive molecules for corneal and ocular surface regenerationAna Kolenc, Živa Dimnik, Miha Marzidovšek, Petra Schollmayer, Marko Hawlina, Elvira Maličev, Zala Lužnik Marzidovšek, 2025, pregledni znanstveni članek Povzetek: Cell-based therapies emerge as potential treatment options for various debilitating diseases. Preclinical research and clinical studies involving cells increased exponentially in the past decade. In addition to cell-based approaches, the use of extracellular vesicles (EVs), which are released by nearly all cell types, emerged as a promising cell-free alternative. Those approaches are also being explored in the field of ophthalmology. Several clinical trials involving EVs are underway to develop potential treatments for advanced ocular surface diseases, including corneal disorders, injuries, and dry eye disease. The cargo carried by EVs has been shown to include a diverse array of functional molecules such as transcription factors, cytokines, growth factors, mRNA, tRNA, rRNA, miRNA, and fragments of dsDNA. While the molecular composition of EVs is already well characterised, the specific activity of these molecules upon delivery to recipient cells remains poorly understood. In this review, we summarise recent studies investigating the bioactive molecules within EVs shown to influence or modulate cellular activity on the ocular surface. Among these, various miRNAs have most commonly been identified as therapeutic agents targeting distinct molecular pathways. The EVs studied were predominantly derived from various mesenchymal stem cells.
Ključne besede: extracellular vesicles, bioactive molecules, cornea, dry eye disease, miRNA, mesenchymal stem cells, ophthalmology
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378. Editorial : databases and nutrition, volume IIAlessandra Durazzo, Igor Pravst, Massimo Lucarini, 2023, predgovor, uvodnik, spremna beseda Ključne besede: food data, food groups, nutrients, natural substances, dietary supplements, classification, categorization, food composition databases
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