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Title:Bolezni, ki jih povzročajo humani virusi papiloma, in preprečevanje s cepljenjem
Authors:ID Uršič-Vrščaj, Marjetka (Author)
Files:.pdf PDF - Presentation file, download (156,64 KB)
MD5: 022930806674F81161CFFAC61FA683AE
PID: 20.500.12556/dirros/b138f698-ebf7-4e17-b65f-d6e9f47a7ee7
 
Language:Slovenian
Typology:1.04 - Professional Article
Organization:Logo OI - Institute of Oncology
Abstract:Okužbe s humanimi virusi papiloma (HPV) so zelo pogoste spolno prenosljive bolezni, ki se značilno pojavijo kmalu po začetku spolne dejavnosti. Breme z njimi povezanih bolezni, rakavih in nerakavih, je veliko za ženske in moške. HPV, ki prinašajo veliko tveganje, visokotvegani ali onkogeni HPV pri ženskah povzročajo raka materničnega vratu, nožnice in zunanjega spolovila, pri moških pa raka penisa ter pomemben delež raka žrela in raka zadnjika pri ženskah in moških. Pred nekaj leti sta bili izdelani cepivi, ki preprečujeta okužbo z 2 genotipoma, ki povzročata raka (HPV 16 in 18). Pri neokuženih osebah v približno 95 % učinkovito preprečujeta bolezni, ki jih povzročata oba genotipa, ne zdravita pa okužbe. Profilaktični cepivi sta prvi, ki so ju naredili, da bi pri človeku preprečevali raka.
Keywords:papiloma virusi, preventivna medicina, cepljenje
Publication status:Published
Publication version:Version of Record
Year of publishing:2011
Number of pages:str. 5-9
Numbering:Letn. 15, št. 1
PID:20.500.12556/DiRROS-8717 New window
UDC:616-006.6
ISSN on article:1408-1741
URN:URN:NBN:SI:doc-69OYN8KU
COBISS.SI-ID:1105787 New window
Copyright:by Authors
Publication date in DiRROS:31.08.2018
Views:3356
Downloads:864
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Record is a part of a journal

Title:Onkologija
Shortened title:Onkologija
Publisher:Onkološki inštitut
ISSN:1408-1741
COBISS.SI-ID:65324032 New window

Licences

License:CC BY 4.0, Creative Commons Attribution 4.0 International
Link:http://creativecommons.org/licenses/by/4.0/
Description:This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Licensing start date:31.08.2018

Secondary language

Language:English
Title:Human Papillomavirus-Related Diseases and Prevention with Vaccination
Abstract:Human papillomavirus (HPV) is an extremely prevalent sexually transmited infection that is typically acquired soon after the onset of sexual activity. The burden of HPV-related malignant and nonmalignant disease is high in women and men. High-risk or oncogenic types of HPV cause cervical, vaginal, and vulvar vancer in women. These types have also been shown to cause penile cancer in men and a substantial proportion of oropharingeal and anal cancer in women and men. Low-risk types of HPV cause anogenital warts. Virus-like particle-based vaccines have recently been developed to prevent the infection with two cancer-associated HPV genotypes (HPV 16, HPV 18) and have been ~ 95% effective in preventing HPV-associated disease caused by genotypes in virus-naive subjects. The prophylactic vaccines are not therapeutic for the already present infection. HPV prophylactic vaccines are the first vaccines designed to prevent a human cancer.


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