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Title:Fluid therapy: double-edged sword during critical care?
Authors:ID Lainščak, Mitja (Author)
ID Voga, Gorazd (Author)
ID Benes, Jan (Author)
ID Kirov, Mikhail (Author)
ID Kuzkov, Vsevolod (Author)
ID Molnar, Zsolt (Author)
ID Monnet, Xavier (Author)
Files:URL URL - Presentation file, visit
Typology:1.02 - Review Article
Organization:Logo SB-CE - General Hospital Celje
Abstract:Fluid therapy is still the mainstay of acute care in patients with shock or cardiovascular compromise. However, our understanding of the critically ill pathophysiology has evolved significantly in recent years.The revelation of the glycocalyx layer and subsequent research has redefined the basics of fluids behavior in the circulation. Using less invasive hemodynamic monitoring tools enables us to assess the cardiovascular function in a dynamic perspective. This allows pinpointing even distinct changes induced by treatment, by postural changes, or by interorgan interactions in real time and enables individualized patient management. Regarding fluids as drugs of any other kind led to the need for precise indication, way of administration, and also assessment of side effects.We possess now the evidence that patient centered outcomes may be altered when incorrect time, dose, or type of fluids are administered. In this review, three major features of fluid therapy are discussed: the prediction of fluid responsiveness, potential harms induced by overzealous fluid administration, and finally the problem of protocol-led treatments and their timing.
Publication status:Published
Publication version:Version of Record
Year of publishing:2015
Number of pages:[str. 1-14]
Numbering:Letn. 2015, čl. 729075
PID:20.500.12556/DiRROS-5828 New window
DOI:10.1155/2015/729075 New window
COBISS.SI-ID:737955 New window
Copyright:© 2015 Jan Benes et al.
Publication date in DiRROS:21.03.2018
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License:CC BY 4.0, Creative Commons Attribution 4.0 International
Description:This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Licensing start date:11.05.2016