| Title: | Two cases of bizarre acquired localised hyperpigmentation disorders – similar yet different diagnostic challenges : two case reports and a brief literature review |
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| Authors: | ID Đorđević Betetto, Laura (Author)
ID Luzar, Boštjan (Author)
ID Bergant, Aleksandra (Author) |
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| Files: |  PDF - Presentation file, download (22,41 MB)
MD5: B3471F88365751C60D0D69996FAF2876
 URL - Source URL, visit https://acta-apa.mf.uni-lj.si/journals/acta-dermatovenerol-apa/papers/10.15570/actaapa.2025.18/actaapa.2025.18.pdf
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| Language: | English |
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| Typology: | 1.03 - Other scientific articles |
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| Organization: |  ZSD - Association of Slovenian Dermatovenereologists
 UKC LJ - Ljubljana University Medical Centre
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| Abstract: | Cutaneous pigmentation disorders are one of the leading causes of dermatological consultation globally. Hyperpigmentation disorders constitute a group of distinct medical conditions that may be either congenital and associated with various concurrent comorbidities, or acquired due to cutaneous, environmental, or systemic conditions or factors. Due to numerous causes and an often atypical clinical picture, diagnosis can be challenging. Furthermore, although the changes in skin color are not inherently harmful, they can result in significant cosmetic disfigurement and have psychological and social repercussions, particularly given that some hyperpigmentation is irreversible due to the limited effectiveness of current treatments. This article presents two cases exhibiting somewhat similar but different acquired localized hyperpigmentation. We review the current literature with emphasis on the diagnostic approach to this entity and specific acquired hyperpigmentation disorders, in particular drug-induced and paraneoplastic. We emphasize the importance of interdisciplinary cooperation among different specialists, particularly in complicated cases and those that accompany systemic diseases. |
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| Keywords: | acquired hyperpigmentation, drug-induced hyperpigmentation, minocycline, POEMS syndrome, monoclonal plasma cell disorder |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Submitted for review: | 06.11.2024 |
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| Article acceptance date: | 15.03.2025 |
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| Publication date: | 01.06.2025 |
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| Place of publishing: | Ljubljana |
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| Publisher: | Združenje slovenskih dermatovenerologov |
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| Year of publishing: | 2025 |
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| Number of pages: | str. 89-93 |
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| Numbering: | Vol. 34, issue 2 |
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| PID: | 20.500.12556/DiRROS-29890  |
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| UDC: | 616.5:579 |
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| ISSN on article: | 1318-4458 |
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| DOI: | 10.15570/actaapa.2025.18 |
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| COBISS.SI-ID: | 243115267 |
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| Copyright: | Na spletni strani revije navedeno: Acta Dermatovenerologica Alpina, Pannonica et Adriatica (ISSN 1318-4458) is an open access medical journal published quarterly by the Association of Slovenian Dermatovenerologists (https://acta-apa.mf.uni-lj.si/index.php); Authors publishing in our journal retain copyright of their work under the Creative Commons Attribution License (CC BY 4.0). This license allows unrestricted use, distribution, and reproduction of the work in any medium, provided the original author(s) and copyright holder(s) are appropriately credited, and the original publication in the journal is properly cited, following established academic practices (https://acta-apa.mf.uni-lj.si/submissions.php). |
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| Publication date in DiRROS: | 09.06.2026 |
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| Views: | 231 |
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| Downloads: | 216 |
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