| Title: | Primary cutaneous CD4-positive small or medium T-cell lymphoproliferative disorder : a case report and literature review |
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| Authors: | ID Trčko, Katarina (Author)
ID Lukinovič, Nuša (Author)
ID Šekoranja, Daja (Author) |
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| Files: |  PDF - Presentation file, download (16,92 MB)
MD5: FFA6837544A02CB88CBBAA547906EB00
 URL - Source URL, visit https://acta-apa.mf.uni-lj.si/journals/acta-dermatovenerol-apa/papers/10.15570/actaapa.2024.29/actaapa.2024.29.pdf
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| Language: | English |
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| Typology: | 1.03 - Other scientific articles |
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| Organization: |  ZSD - Association of Slovenian Dermatovenereologists
 UKC LJ - Ljubljana University Medical Centre
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| Abstract: | Primary cutaneous CD4-positive small or medium T-cell lymphoproliferative disorder (PCSM-LPD) is characterized by a slow-growing and asymptomatic solitary plaque or tumor, usually involving the head, neck, or upper extremities. The diagnosis is established based on clinical presentation, histopathological features including pleomorphic morphology and CD4-positive immunophenotype of neoplastic T lymphocytes, and molecular analysis showing clonally rearranged T-cell receptor (TCR) genes. Plaques typical of mycosis fungoides are essentially absent. Treatment options include surgical excision, radiotherapy, and topical or intralesional steroids. Because the disease is indolent, aggressive diagnostic tests and systemic treatments are not recommended. We present a case of PCSM-LPD in a previously healthy young man that spontaneously regressed after a biopsy. |
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| Keywords: | primary cutaneous CD4-positive small or medium T-cell lymphoproliferative disorder, primary cutaneous lymphoma, T-cell lymphoma, lymphoproliferative disorder, spontaneous regression |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Submitted for review: | 16.09.2024 |
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| Article acceptance date: | 11.10.2024 |
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| Publication date: | 01.06.2025 |
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| Place of publishing: | Ljubljana |
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| Publisher: | Združenje slovenskih dermatovenerologov |
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| Year of publishing: | 2025 |
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| Year of performance: | 2025 |
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| Number of pages: | str. 79-82 |
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| Numbering: | Vol. 34, issue 2 |
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| PID: | 20.500.12556/DiRROS-29885  |
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| UDC: | 616.5 |
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| ISSN on article: | 1318-4458 |
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| DOI: | 10.15570/actaapa.2024.29 |
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| COBISS.SI-ID: | 220499203 |
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| Copyright: | Na spletni strani revije navedeno: Acta Dermatovenerologica Alpina, Pannonica et Adriatica (ISSN 1318-4458) is an open access medical journal published quarterly by the Association of Slovenian Dermatovenerologists (https://acta-apa.mf.uni-lj.si/index.php); Authors publishing in our journal retain copyright of their work under the Creative Commons Attribution License (CC BY 4.0). This license allows unrestricted use, distribution, and reproduction of the work in any medium, provided the original author(s) and copyright holder(s) are appropriately credited, and the original publication in the journal is properly cited, following established academic practices (https://acta-apa.mf.uni-lj.si/submissions.php). |
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| Publication date in DiRROS: | 09.06.2026 |
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| Views: | 228 |
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| Downloads: | 221 |
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