| Title: | The Influence of COVID-19 on antimicrobial resistance trends at a secondary care hospital in Slovenia : an Interrupted Time Series Analysis |
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| Authors: | ID Jeverica, Samo (Author)
ID Barlič-Maganja, Darja (Author)
ID Dernič, Jani (Author)
ID Golob, Peter (Author)
ID Stepišnik, Alenka (Author)
ID Novak, Bojan (Author)
ID Papst, Lea (Author)
ID Juriševič Dodič, Anamarija (Author)
ID Gasparini, Mladen (Author) |
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| Files: |  PDF - Presentation file, download (1,75 MB)
MD5: 352C946A629492269773A54A60111B99
 URL - Source URL, visit https://www.mdpi.com/2079-6382/13/11/1033
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| Language: | English |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: |  UKC LJ - Ljubljana University Medical Centre
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| Abstract: | We analyzed data from seven years, accounting for 441,149 patient days. The incidence density of multidrug-resistant bacteria (MDR) burden and infection was reported per 1000 patient days. Results. During COVID-19, a significant increase in the mean incidence density of the total MDR burden from 4.93 to 5.81 per 1000 patient days was observed (p = 0.007). On the other hand, the mean incidence density of MDR infections decreased from 1.61 to 1.29 per 1000 patient days (p = 0.019). Using the interrupted time series analysis, the same trends were observed, namely the overall increasing trend in MDR burden and the overall decreasing trend in MDR infections. This divergent trend is mainly due to similar trends in several Gram-negative MDR, namely ESBL-EC, ESBL-KP and CRE. Due to the increasing burden of MDR, it is necessary to strengthen AMR surveillance. In addition, strict infection prevention and control measures, and antimicrobial stewardship programs continue to be important. |
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| Keywords: | antimicrobial resistance, COVID-19, Slovenia, interrupted time series analysis |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Year of publishing: | 2024 |
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| Number of pages: | 10 str. |
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| Numbering: | Vol. 13, iss. 11, [article] 1033 |
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| PID: | 20.500.12556/DiRROS-29721  |
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| UDC: | 579 |
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| ISSN on article: | 2079-6382 |
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| COBISS.SI-ID: | 214692355 |
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| Note: | Nasl. z nasl. zaslona;
Opis vira z dne 12. 11. 2024;
Št. članka: 1033;
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| Publication date in DiRROS: | 03.06.2026 |
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| Views: | 40 |
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| Downloads: | 19 |
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| Metadata: |    |
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