| Title: | Exploring BPA alternatives : environmental levels and toxicity review |
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| Authors: | ID Adamovsky, Ondrej (Author)
ID Groh, Ksenia J (Author)
ID Białk-Bielińska, Anna (Author)
ID Escher, Beate I. (Author)
ID Beaudouin, R. (Author)
ID Mora Lagares, Liadys (Author)
ID Tollefsen, K. E. (Author)
ID Štern, Alja (Author)
ID Eleršek, Tina (Author)
ID Vračko, Marjan (Author)
ID Žegura, Bojana (Author) |
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| Files: |  URL - Source URL, visit https://doi.org/10.1016/j.envint.2024.108728
 PDF - Presentation file, download (1,64 MB)
MD5: 76D7CA4A1A8A7F9D6D1C0E456799A8E0
PDF - Presentation file, download (3,85 MB)
MD5: 0DB1D0F9ABC465BEF93B53E3BD6DE885
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| Language: | English |
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| Typology: | 1.02 - Review Article |
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| Organization: |  NIB - National Institute of Biology
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| Abstract: | Bisphenol A alternatives are manufactured as potentially less harmful substitutes of bisphenol A (BPA) that offer similar functionality. These alternatives are already in the market, entering the environment and thus raising ecological concerns. However, it can be expected that levels of BPA alternatives will dominate in the future, they are limited information on their environmental safety. The EU PARC project highlights BPA alternatives as priority chemicals and consolidates information on BPA alternatives, with a focus on environmental relevance and on the identification of the research gaps. The review highlighted aspects and future perspectives. In brief, an extension of environmental monitoring is crucial, extending it to cover BPA alternatives to track their levels and facilitate the timely implementation of mitigation measures. The biological activity has been studied for BPA alternatives, but in a non-systematic way and prioritized a limited number of chemicals. For several BPA alternatives, the data has already provided substantial evidence regarding their potential harm to the environment. We stress the importance of conducting more comprehensive assessments that go beyond the traditional reproductive studies and focus on overlooked relevant endpoints. Future research should also consider mixture effects, realistic environmental concentrations, and the long-term consequences on biota and ecosystems. |
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| Keywords: | BPA alternatives, biological activity, in silico, invertebrates, vertebrates, toxicity |
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| Publication status: | In print |
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| Publication version: | Author Accepted Manuscript |
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| Publication date: | 23.05.2024 |
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| Year of publishing: | 2024 |
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| PID: | 20.500.12556/DiRROS-19035  |
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| UDC: | 615.9 |
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| ISSN on article: | 0160-4120 |
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| DOI: | 10.1016/j.envint.2024.108728 |
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| COBISS.SI-ID: | 197535491 |
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| Note: | Soavtorji: Ksenia J. Groh, Anna Białk-Bielińska, Beate I. Escher, R. Beaudouin, L. Mora Lagares, K.E. Tollefsen, Martina Fenske, Ewa Mulkiewicz, Nicolas Creusot, Anita Sosnowska, Susana Loureiro, Jonny Beyer, Guillermo Repetto, Alja Štern, Isabel Lopes, Marta Monteiro, Andrea Zikova-Kloas, Tina Eleršek, Marjan Vračko, Szymon Zdybel, Tomasz Puzyn, Weronika Koczur, Jane Ebsen Morthorst, Henrik Holbec, Gunnar Carlsson, Stefan Örn, Óscar Herrero, Ayesha Siddique, Matthias Liess, Georg Braun, Vanessa Srebny, Bojana Žegura, Nathalie Hinfray, François Brion et al.;
Online first: 23 May 2024;
Članek v PDF formatu obsega 72 str.;
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| Publication date in DiRROS: | 03.06.2024 |
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| Views: | 470 |
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| Downloads: | 375 |
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