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Title:Reorganization of microtubules in V-79 cells after treatment with cytohalasin B
Authors:ID Iglič, Aleš (Author)
ID Batista, Urška (Author)
ID Veranič, Peter (Author)
Files:.pdf PDF - Presentation file, download (442,36 KB)
MD5: BFC127C24FE50D3517DDC47021BD34B2
 
Language:English
Typology:1.01 - Original Scientific Article
Organization:Logo OI - Institute of Oncology
Abstract:Background. The aim of this work was to study the configuration of the microtubules in the cytochalasin B treated V-79 cells in connection to the cell shape and to see whether there are any similarities to the phenomena taking place in phospholipid vesicles. Subjects and methods. An experiment wasperformed where cytochalasin B was added to the V-79 cells (lung fibroblasts of Chinese hamster). Results. The cell shape changed from an elongated one into the shape with a profile resembling the Greek letter phi. The microtubules were found to be organized into a rod within the symmetry axis of the cell. Conclusion. As similar shapes were previously observed also in the phospholipid vesicles with entrapped microtubule rods, our results support the hypothesis that similar physical mechanisms may pertain in simple systems as well as in living cells.
Publication status:Published
Publication version:Version of Record
Publication date:01.12.1999
Publisher:Slovenian Medical Association - Slovenian Association of Radiology, Nuclear Medicine Society, Slovenian Society far Radiotherapy and Oncology, and Slovenian Cancer Society
Year of publishing:1999
Number of pages:str. 297-301
Numbering:Letn. 33, št. 4
Source:Ljubljana
PID:20.500.12556/DiRROS-17929 New window
UDC:616-006
ISSN on article:1318-2099
COBISS.SI-ID:11071961 New window
Copyright:by Authors
Note:BSDOCID49540;
Publication date in DiRROS:22.01.2024
Views:617
Downloads:128
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Record is a part of a journal

Title:Radiology and oncology
Shortened title:Radiol. oncol.
Publisher:Slovenian Medical Society - Section of Radiology, Croatian Medical Association - Croatian Society of Radiology
ISSN:1318-2099
COBISS.SI-ID:32649472 New window

Secondary language

Language:Slovenian
Title:Razporejanje mikrotubulov v celicah V-79 po delovanju citohalazina B
Abstract:Izhodišča. V tej raziskavi smo proučevali razporeditev mikrotubulov celicah V-79 po delovanju citohalazina B. Poleg njihove oblike smo poskušali ugotoviti, ali je ta pojav v čemer koli podoben dogajanjem v fosfolipidnih mehurčkih. Material in metode. Opravili smo preiskus s citohalazinom B, ki smoga dodali celicam V 79 (pljučni fibroblasti kitajskega hrčka). Rezultati. Oblika celice se je spremenila iz podolgovate v obliko, katere profil je podoben grški črki fi. Mikrotubuli so se uredili v palico v simetrijski osi celice. Zaključek. Ker so podobne oblike pred tem opazili tudi pri fosfolipidnih mehurčkih, ki so vsebovali paličasto strukturo iz mikrotubulov, prikazani rezultati podpirajo hipotezo, da so podobni fizikalni mehanizmi prisotni v preprostih sistemih kot tudi v živih celicah.


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