Your browser does not allow JavaScript!
JavaScript is necessary for the proper functioning of this website. Please enable JavaScript or use a modern browser.
Digital repository of Slovenian research organisations
About
Search
Browse
Statistics
Contacts
Login
Show document
A+
|
A-
|
|
SLO
|
ENG
Title:
Rezultati študije RAPIDO
Authors:
ID
Edhemović, Ibrahim
(Author)
Files:
PDF - Presentation file,
download
(86,79 KB)
MD5: 1A39D397103801B68B62BF3693677F56
Language:
Slovenian
Typology:
1.08 - Published Scientific Conference Contribution
Organization:
OI - Institute of Oncology
Abstract:
3-letno preživetje brez bolezni pri bolnikih z lokalno napredovalim rakom danke je trenutno približno 50 %. Standardno zdravljenje bolnikov z visokim tveganjem za lokalno in/ali sistemsko ponovitev bolezni vključuje predoperativno radioterapijo po dolgem protokolu (5 tednov) v kombinaciji s kemoterapijo (neoadjuvantna kemoradioterapija). Dokazano je, da neoadjuvantna kemoradioterapija izboljša lokalno kontrolo, vendar ne vpliva na preživetje. Sistemski recidivi ostajajo velik problem pri lokalno napredovalem raku danke. Z namenom zmanjšanja oddaljenih metastaz brez ogrožanja lokoregionalnega nadzora z uporabo radioterapije po kratkem režimu, ki ji sledi kemoterapija in odložena operacija je bila sestavljena in izvedena študija RAPIDO (Rectal cancer And Preoperative Induction therapy followed by Dedicated Operation – RAPIDO). Šlo je za multicentrično, mednarodno študijo faze 3 v kateri je sodelovalo 54 onkoloških centrov med katerimi tudi Onkološki inštitut v Ljubljani.
Keywords:
rak danke
,
onkološko zdravljenje
,
klinične študije
Publication status:
Published
Publication version:
Version of Record
Place of publishing:
Ljubljana
Publisher:
Onkološki inštitut
Year of publishing:
2022
Number of pages:
Str. 103-105
PID:
20.500.12556/DiRROS-16068-39708ed5-2d64-47d5-77c6-39fda3c59153
UDC:
616.3
COBISS.SI-ID:
135702019
Copyright:
by Author
Note:
Nasl. z nasl. zaslona; Opis vira z dne 29. 12. 2022;
Publication date in DiRROS:
16.01.2023
Views:
628
Downloads:
136
Metadata:
Cite this work
Plain text
BibTeX
EndNote XML
EndNote/Refer
RIS
ABNT
ACM Ref
AMA
APA
Chicago 17th Author-Date
Harvard
IEEE
ISO 690
MLA
Vancouver
:
Copy citation
Share:
Hover the mouse pointer over a document title to show the abstract or click on the title to get all document metadata.
Record is a part of a monograph
Title:
Tumorji prebavil : Standardi in perspektive
Editors:
Marko Boc, Tanja Mesti
Place of publishing:
Ljubljana
Publisher:
Onkološki inštitut, Sekcija za internistično onkologijo, Katedra za onkologijo
Year of publishing:
2022
ISBN:
978-961-7029-55-0
COBISS.SI-ID:
133694211
Secondary language
Language:
English
Title:
Results of the RAPIDO study
Abstract:
The 3-year disease-free survival rate for patients with locally advanced rectal cancer is currently approximately 50%. Standard treatment for patients at high risk of local and/or systemic disease recurrence includes preoperative radiotherapy following a long protocol (5 weeks) in combination with chemotherapy (neoadjuvant chemoradiotherapy). Neoadjuvant chemoradiotherapy has been shown to improve local control but not to affect survival. Systemic recurrences remain a major problem in locally advanced rectal cancer. The RAPIDO (Rectal cancer And Preoperative Induction therapy followed by Dedicated Operation - RAPIDO) study was designed and implemented with the aim of reducing distant metastases without jeopardizing locoregional control by using radiotherapy after a short regimen, followed by chemotherapy and delayed surgery. It was a multicenter, international phase 3 study in which 54 oncology centers participated, including the Oncology Institute in Ljubljana.
Keywords:
rectal cancer
,
the RAPIDO study
Back