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Title:Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)
Authors:Vincent, Jean Louis (Author)
Lefrant, Jean-Yves (Author)
Kotfis, Katarzyna (Author)
Nanchal, Rahul (Author)
Martin-Loeches, Ignacio (Author)
Sakka, Samir G. (Author)
Wittebole, Xavier (Author)
Pickkers, Peter (Author)
Moreno, Rui P. (Author)
Sakr, Yasser (Author)
Tomič, Viktorija (Other)
Tipology:1.01 - Original Scientific Article
Organisation:Logo UKPBAG - University Clinic of Respiratory and Allergic Diseases Golnik
Abstract:Purpose: To evaluate differences in the characteristics and outcomes of intensive care unit (ICU) patients over time. Methods: We reviewed all epidemiological data, including comorbidities, types and severity of organ failure, interventions, lengths of stay and outcome, for patients from the Sepsis Occurrence in Acutely ill Patients (SOAP) study, an observational study conducted in European intensive care units in 2002, and the Intensive Care Over Nations (ICON) audit, a survey of intensive care unit patients conducted in 2012. Results: We compared the 3147 patients from the SOAP study with the 4852 patients from the ICON audit admitted to intensive care units in the same countries as those in the SOAP study. The ICON patients were older (62.5 +/- 17.0 vs. 60.6 +/- 17.4 years) and had higher severity scores than the SOAP patients. The proportion of patients with sepsis at any time during the intensive care unit stay was slightly higher in the ICON study (31.9 vs. 29.6%, p = 0.03). In multilevel analysis, the adjusted odds of ICU mortality were significantly lower for ICON patients than for SOAP patients, particularly in patients with sepsis [OR 0.45 (0.35-0.59), p < 0.001]. Conclusions: Over the 10-year period between 2002 and 2012, the proportion of patients with sepsis admitted to European ICUs remained relatively stable, but the severity of disease increased. In multilevel analysis, the odds of ICU mortality were lower in our 2012 cohort compared to our 2002 cohort, particularly in patients with sepsis.
Keywords:intensive care units -- analysis -- epidemiology -- mortality, sepsis, severity of disease
Year of publishing:2018
COBISS_ID:2048262001 Link is opened in a new window
ISSN on article:1432-1238
OceCobissID:512019481 Link is opened in a new window
DOI:10.1007/s00134-017-5043-2 Link is opened in a new window
Note:Soavtorji: Jean-Yves Lefrant, Katarzyna Kotfis, Rahul Nanchal, Ignacio Martin-Loeches, Xavier Wittebole, Samir G. Sakka, Peter Pickkers, Rui Moreno, Yasser Sakr, on behalf of the ICON and SOAP investigators; Nasl. z nasl. zaslona; Opis vira z dne 20. 3. 2018;
Files:.pdf PDF - Presentation file, download (867,51 KB)
.docx DOCX - Supplement, download (1,33 MB)
URL URL - Source URL, visit
Journal:Intensive care med.
Rights:© 2018 The Author(s).
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License:CC BY-NC 4.0, Creative Commons Attribution Non-Commercial 4.0 International
Description:A creative commons license that bans commercial use, but the users don’t have to license their derivative works on the same terms.
Licensing start date:15.02.2018