20.500.12556/DiRROS-12789 Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP) Purpose: To evaluate differences in the characteristics and outcomes of intensive care unit (ICU) patients over time. Methods: We reviewed all epidemiological data, including comorbidities, types and severity of organ failure, interventions, lengths of stay and outcome, for patients from the Sepsis Occurrence in Acutely ill Patients (SOAP) study, an observational study conducted in European intensive care units in 2002, and the Intensive Care Over Nations (ICON) audit, a survey of intensive care unit patients conducted in 2012. Results: We compared the 3147 patients from the SOAP study with the 4852 patients from the ICON audit admitted to intensive care units in the same countries as those in the SOAP study. The ICON patients were older (62.5 +/- 17.0 vs. 60.6 +/- 17.4 years) and had higher severity scores than the SOAP patients. The proportion of patients with sepsis at any time during the intensive care unit stay was slightly higher in the ICON study (31.9 vs. 29.6%, p = 0.03). In multilevel analysis, the adjusted odds of ICU mortality were significantly lower for ICON patients than for SOAP patients, particularly in patients with sepsis [OR 0.45 (0.35-0.59), p < 0.001]. Conclusions: Over the 10-year period between 2002 and 2012, the proportion of patients with sepsis admitted to European ICUs remained relatively stable, but the severity of disease increased. In multilevel analysis, the odds of ICU mortality were lower in our 2012 cohort compared to our 2002 cohort, particularly in patients with sepsis. intensive care units -- analysis -- epidemiology -- mortality sepsis severity of disease enote intenzivne terapije -- analiza -- epidemiologija -- umrljivost sepsa resnost bolezni true false true Springer Angleški jezik Ni določen © 2018 The Author(s). Neznano 2020-11-30 11:33:11 2020-11-30 11:33:12 2022-08-19 03:34:58 0000-00-00 00:00:00 2018 0 Nemčija 0 Soavtorji: Jean-Yves Lefrant, Katarzyna Kotfis, Rahul Nanchal, Ignacio Martin-Loeches, Xavier Wittebole, Samir G. Sakka, Peter Pickkers, Rui Moreno, Yasser Sakr, on behalf of the ICON and SOAP investigators; Nasl. z nasl. zaslona; Opis vira z dne 20. 3. 2018; str. 337-344 iss. 3 Vol. 44 Mar. 2018 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 614.2 1432-1238 10.1007/s00134-017-5043-2 2048262001 512019481 RAZ_Vincent_Jean_Louis_i2018.pdf RAZ_Vincent_Jean_Louis_i2018.pdf 1 53F9398B0659ABD804D8820B9D3C99AE 2041ea47b1a78fa24eb4001e4b4b84983462dc4a78c347c2cbeb90e6e6c18d6b 84f1ecb6-17b6-11ed-b6b8-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=17158 RAZ_Vincent_Jean_Louis_i2018.docx RAZ_Vincent_Jean_Louis_i2018.docx 1 1986FF4BC04E5499218EC540C560044A d0d6ab0cad35fab476a0e2a7d2d0ec84e290d215546dc7292ecb97631b2920e2 85008d14-17b6-11ed-b6b8-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=17159 https://link.springer.com/content/pdf/10.1007%2Fs00134-017-5043-2.pdf 1 https://dirros.openscience.si/Dokument.php?lang=slv&id=15649 Univerzitetna klinika za pljučne bolezni in alergijo Golnik 0 0 0